Results 261 to 270 of about 1,044,819 (294)
Some of the next articles are maybe not open access.
Nature Cell Biology, 2017
Previous work has highlighted the role of metabolic shifts in regulating the formation of memory T cells, which are generated during a primary infection to provide long-lasting immunity. A study now shows that memory T cells rely on a gluconeogenesis–glycogenolysis cycle to provide antioxidant defence and support their survival.
Joanna, Olivas, Tiffany, Horng
openaire +2 more sources
Previous work has highlighted the role of metabolic shifts in regulating the formation of memory T cells, which are generated during a primary infection to provide long-lasting immunity. A study now shows that memory T cells rely on a gluconeogenesis–glycogenolysis cycle to provide antioxidant defence and support their survival.
Joanna, Olivas, Tiffany, Horng
openaire +2 more sources
Immunological Reviews, 2006
Summary: The pool of memory T cells is regulated by homeostatic mechanisms to persist for prolonged periods at a relatively steady overall size. Recent work has shown that two members of the common γ chain (γc) family of cytokines, interleukin‐7 (IL‐7) and IL‐15, govern homeostasis of memory T cells.
Charles D, Surh +3 more
openaire +2 more sources
Summary: The pool of memory T cells is regulated by homeostatic mechanisms to persist for prolonged periods at a relatively steady overall size. Recent work has shown that two members of the common γ chain (γc) family of cytokines, interleukin‐7 (IL‐7) and IL‐15, govern homeostasis of memory T cells.
Charles D, Surh +3 more
openaire +2 more sources
1990
Generally, it is accepted that immunological memory exists at both the B- and the T-cell level (reviewed in Katz 1977). It has been known for more than 100 years that the persistence of high antibody titers (Fig. 1) can be lifelong after viral infections and that delayed-type hypersensitivity can be demonstrated for a long time by challenging with a ...
openaire +2 more sources
Generally, it is accepted that immunological memory exists at both the B- and the T-cell level (reviewed in Katz 1977). It has been known for more than 100 years that the persistence of high antibody titers (Fig. 1) can be lifelong after viral infections and that delayed-type hypersensitivity can be demonstrated for a long time by challenging with a ...
openaire +2 more sources
T-cell memory: new perspectives
Immunology Today, 1993Immunological memory provides excellent protection against a wide variety of different pathogens. Compared to the primary encounter with antigen, the secondary response is more rapid and effective. So much so, that reexposure often goes unnoticed by the host.
L M, Bradley, M, Croft, S L, Swain
openaire +2 more sources
Annual Review of Immunology, 1991
Three remarkable and unique features of the immune system are specificity, diversity, and memory. Immunological memory involves both T and B cells and results in a secondary antibody response that is faster, of higher affinity, and results in the secretion of non-IgM isotypes of Ig.
E S, Vitetta +5 more
openaire +2 more sources
Three remarkable and unique features of the immune system are specificity, diversity, and memory. Immunological memory involves both T and B cells and results in a secondary antibody response that is faster, of higher affinity, and results in the secretion of non-IgM isotypes of Ig.
E S, Vitetta +5 more
openaire +2 more sources
2010
1. Memory Th1/Th2 Cell Generation Controlled by Schnurri?2 Toshinori Nakayama and Motoko Y. Kimura Abstract Introduction Schnurri Family Genes Shn?3 Shn?2 Role of Shn?2 in Naive CD4 T and Effector Th2 Cells Role of Shn?2 in The Generation of Memory Th1/Th2 Cells NF??B Overexpression in Effector Th Cells Results in the Decreased Generation of Memory Th ...
openaire +1 more source
1. Memory Th1/Th2 Cell Generation Controlled by Schnurri?2 Toshinori Nakayama and Motoko Y. Kimura Abstract Introduction Schnurri Family Genes Shn?3 Shn?2 Role of Shn?2 in Naive CD4 T and Effector Th2 Cells Role of Shn?2 in The Generation of Memory Th1/Th2 Cells NF??B Overexpression in Effector Th Cells Results in the Decreased Generation of Memory Th ...
openaire +1 more source
Immunological memory in T cells
Current Opinion in Immunology, 1991CD4 and CD8 T lymphocytes can be further subdivided using antibodies to isoforms of CD45 with restricted cellular distributions. These further subsets, detected in man, rodents and sheep, differ in surface phenotypes, rate of cycling, migration and response to recall antigens. Their lineage relationship has still not been fully established.
openaire +2 more sources
T Memory Cells in a Model of T Cell Memory
1992T lymphocytes can be separated into two phenotypes according to whether or not they bear a high molecular weight isoform of the leucocyte common antigen CD45 (Akbar et al 1988). This phenotypic dichotomy is matched by a functional dichotomy: it has been suggested that cells bearing the heavier isoform (CD45R+) are an unprimed population whilst those ...
openaire +1 more source
The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues
Nature Reviews Immunology, 2021Lianne Kok +2 more
exaly