Results 131 to 140 of about 2,133 (253)

Discriminating Chemoresistant and Chemosensitive Tubo‐Ovarian High‐Grade Serous Carcinoma Cells With Raman Microscopy

open access: yesJournal of Raman Spectroscopy, EarlyView.
Confocal Raman microscopy combined with multivariate analysis distinguishes cisplatin‐resistant and ‐sensitive tubo‐ovarian high‐grade serous carcinoma cell lines. ABSTRACT Chemoresistance is a major obstacle to effective cancer treatment, particularly in tubo‐ovarian high‐grade serous carcinoma (HGSC), the most lethal gynaecological malignancy ...
Elina Harju   +13 more
wiley   +1 more source

Non‐Uniform Programmable Photonic Waveguide Meshes

open access: yesLaser &Photonics Reviews, EarlyView.
Integrating defect cells into uniform hexagonal waveguide meshes overcomes the fundamental spectral and temporal limitations of programmable photonics. By leveraging the Vernier effect through non‐uniform coupled cavities, this architecture achieves a tenfold increase in free spectral range and ultra‐fast sampling times, paving the way for next ...
Cristina Catalá‐Lahoz, José Capmany
wiley   +1 more source

Integrated Photonic Modulator Circuit With Programmable Intensity and Phase Modulation Response

open access: yesLaser &Photonics Reviews, EarlyView.
A platform‐agnostic programmable modulation circuit is introduced to enable tunable and universal optimization of integrated photonic modulators. By flexibly controlling carrier amplitude and phase, the approach adapts to diverse device characteristics without structural redesign.
Hong Deng   +3 more
wiley   +1 more source

Biomimetic Multifinger Tactile Sensing and Contact‐Regulated Palpation for Autonomous Breast Tumor Localization

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Early detection of breast abnormalities remains challenging: manual palpation is subjective and operator‐dependent, while imaging modalities may miss small or subtle stiffness anomalies. This paper presents a biomimetic multifinger robotic palpation approach intended to support early breast‐cancer screening and follow‐up assessment as a proof ...
Kai Cheng   +7 more
wiley   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

open access: yesSmall, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom   +6 more
wiley   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig   +7 more
wiley   +1 more source

Deep learning-driven performance prediction and design of high-DoF MEMS resonators. [PDF]

open access: yesMicrosyst Nanoeng
Jia Z   +13 more
europepmc   +1 more source

Impact of Oral Sebetralstat on Anxiety Associated With Hereditary Angioedema Attacks

open access: yesClinical &Experimental Allergy, EarlyView.
In the phase 3 KONFIDENT trial of oral sebetralstat for on‐demand treatment of hereditary angioedema attacks, many attacks induced moderate‐to‐extreme anxiety. Sebetralstat reduced anxiety versus placebo; time to reductions agreed with trial endpoints, such as time to beginning of symptom relief.
Timothy Craig   +24 more
wiley   +1 more source

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