Results 151 to 160 of about 248,446 (274)

Bidirectional and Multivariable Mendelian Randomization Study of PCOS and VTE. [PDF]

Int J Womens Health
You L, Cui H, Zhao F, Huang H, Xu W.
europepmc   +1 more source

Mendelian gene

Citation: 'Mendelian gene' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10929 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source

No causal effect between prostatitis and erectile dysfunction: Insights from a 2-sample bidirectional Mendelian randomization study. [PDF]

Medicine (Baltimore)
Dai X, Huang J, Ding H, Xie Y.
europepmc   +1 more source

Association between life course adiposity and diabetic microvascular complications: A univariable and multivariable Mendelian randomization study. [PDF]

Medicine (Baltimore)
Ma J, Hao M, Yao J, Li Y, Liu T.
europepmc   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Moving Mendelian Randomization From Traditional Risk Factors to Molecular Targets for Drug Development and Clinical Trials in Nephrology. [PDF]

Kidney Int Rep
Berube AJ, Yu E, Gaheer PS, Lanktree MB.
europepmc   +1 more source

Correlation Between Gut Microbiota, Metabolites, and Diabetic Complications: A Two‐Sample Mendelian Randomization Study

Medicine Advances, EarlyView.
Fang et al. demonstrate a significant causal relationship among gut microbiota, gut metabolites, and diabetic complications, highlighting a biological link underlying mechanisms of diabetic vascular diseases. These findings provide important implications for future therapeutic strategy and risk prediction.
Jiaxi Fang, Leilei Zhai, Chan Huang, Liqin Li, Yong Wang, Jiaojiao Fan, Wei Zhou   +6 more
wiley   +1 more source

Evaluating a Mendelian Risk Prediction Model That Aggregates Across Genes and Cancers. [PDF]

Genet Epidemiol
Liang JW, Idos GE, Hong C, Shannon KM, Bear LM, Pichardo JM, Guan Z, McCarthy AM, Ford JM, Kurian AW, Gruber SB, Braun D, Parmigiani G.   +12 more
europepmc   +1 more source

Emerging Upper Extremity Muscle Ultrasound Patterns as a Diagnostic Aid in TTN‐Related Myopathies

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Biallelic pathogenic variants in TTN cause rare forms of early‐onset myopathy, manifesting with variable severity, distribution, and progression of muscle weakness, often associated with respiratory insufficiency and potentially cardiomyopathy. The large size of TTN and phenotypic heterogeneity in TTN‐related myopathy (TTN‐RM)
Abigail Potticary, Meghan McAnally, Sandra Donkervoort, Carsten G. Bönnemann   +3 more
wiley   +1 more source

Hyperthyroidism drives gout risk: A Mendelian randomization observational study. [PDF]

Medicine (Baltimore)
Pan Y, Zhou S, Luo D.
europepmc   +1 more source