Results 171 to 180 of about 133,969 (268)

A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies

Addiction, EarlyView.
Abstract Background and aims Evidence on the causal impact and corresponding risk relationships between dimensions of alcohol consumption and health outcomes continues to evolve, with some contradictory findings across study designs. This review aimed to update current knowledge on causality and risk relationships to inform global and national ...
Sinclair Carr, Ana Lucia Espinosa Dice, Gerhard E. Gmel Sr., Ahmed S. Hassan, Kevin D. Shield, Jürgen Rehm   +5 more
wiley   +1 more source

Causal relationships between salt intake and gastric cancer: A two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Li K, Wu J, Lai S, Yu L, Zhou H, Qian J, Wu Q.   +6 more
europepmc   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Bidirectional Mendelian randomization explores the causal relationship between arthritis and cerebral cortical volume. [PDF]

Medicine (Baltimore)
Zhou Y, Sun F, Peng D, Xu W, Zou Q, Jiang Z.   +5 more
europepmc   +1 more source

Risks of gynecological and breast cancers in women with endometriosis or adenomyosis: A nationwide cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Endometriosis (including adenomyosis) is an inflammatory disease with lesions of endometrial tissue outside the uterus or in the uterine wall. In this study on Swedish women, endometriosis or adenomyosis was associated with persistently increased risks of breast and epithelial ovarian cancers, especially clear cell, endometrioid, and low‐grade serous ...
Louise Moberg, Xinjun Li, Filip Herbst, Filip Jansåker, Arturas Dobilas, Kristina Sundquist, Christer Borgfeldt   +6 more
wiley   +1 more source

Bidirectional mediation between microbiota and immune system in Parkinson disease: A two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Qu T, Zhao Q, Fang J, Liang Z.
europepmc   +1 more source

Variation in measuring and ophthalmic factors correlating with central corneal thickness in the Northern Finland birth cohort eye study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the correlation between optical coherence tomography (OCT) and ultrasound pachymetry (USP) as methods for analysing central corneal thickness (CCT) and to evaluate ophthalmic factors affecting CCT. Methods The eyes of 3070 subjects of the Northern Finland Birth Cohort (NFBC) were examined at the age of 45–49 years.
Tuomas Qvist, Oona Ahokas, Johanna Liinamaa, Ville Saarela   +3 more
wiley   +1 more source

Causality analysis of fatty acids, triglycerides and psoriasis based on Mendelian randomization. [PDF]

Medicine (Baltimore)
Long J, Deng C, Huang M, Tang L, Li Q, Wang F, Lin Y.   +6 more
europepmc   +1 more source

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer, Kristina Lagerstedt‐Robinson, Daniel Nilsson, Cilla Söderhäll, Björn Hammar, Erik Björck   +5 more
wiley   +1 more source

Causal effects between blood metabolites and myocardial infarction: A 2-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Fu Y, Wei A, Wu W, Peng Z.
europepmc   +1 more source