Results 181 to 190 of about 248,446 (274)

Mendelian randomization study finds no causal link between inflammatory bowel disease and cirrhosis. [PDF]

Medicine (Baltimore)
An J, Zhu M, Fu Y, Gao K, Xie H, Ding H, Guo C, Zeng F, Xiong Y.   +8 more
europepmc   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu, Jia‐Yao Zhou, Shi‐Yao Zhang, Ru Tang, Chun‐Yu Luo, Yue‐Long Gu, Zhi‐Peng Li, Wei‐Tian Zhang   +7 more
wiley   +1 more source

Interpretable machine learning in type-2 diabetes prediction in patients with depressive symptoms: Insights from mendelian randomization and physical activity. [PDF]

Sci Prog
Li Z, Qiu X, Wu W, Kang H.
europepmc   +1 more source

Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA) is a common chronic disorder characterized by abnormal breathing during sleeping. OSA can damage various organs throughout the body and is burdensome, both socially and economically. Moreover, as OSA has been increasingly studied in recent years, new evidence‐based guidelines for its diagnosis and surgical ...
Working Group of Guideline for the Diagnosis and Surgical Treatment of Adult OSA, Subspecialty Group of Laryngopharyngology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Subspecialty Group of Voice, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery   +7 more
wiley   +1 more source

Genetically determined causality between immune cells and anxiety disorders: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Liu J, Liang P, Wang Y, Huang H, Zhang S, Li G, Wu H.   +6 more
europepmc   +1 more source

Obstructive Sleep Apnea and BMI, Body Fat Percentage in the East Asian Population: A Bidirectional and Multivariate Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the causal relationship between obstructive sleep apnea and body fat percentage and body mass index (BMI) in the East Asian population by using bidirectional Mendelian randomization and multivariate Mendelian randomization.
Rui Fan, Wen‐Jun Lu, Hua Zhang, Hai‐Ling Jiang, Tao Li, Yan Yan   +5 more
wiley   +1 more source

A bidirectional 2-sample Mendelian randomization study of depressed mood and premature ovarian insufficiency. [PDF]

Medicine (Baltimore)
Chen K, Wan L, Wang X, Ma X, Chen Y, Han L.   +5 more
europepmc   +1 more source

Eco‐evolutionary dynamics of partially migratory metapopulations in spatially and seasonally varying environments

Journal of Animal Ecology, EarlyView.
Partial seasonal migration is rarely considered in a metapopulation context. Here, Haaland et al. use an eco‐evolutionary model revealing how partially migratory metapopulations may arise and be maintained, and how seasonal migrants may cause effects of local extreme climatic events to percolate through metapopulations across diverging temporal and ...
Thomas R. Haaland, Ana Payo‐Payo, Paul Acker, Rita Fortuna, Sarah J. Burthe, Irja I. Ratikainen, Francis Daunt, Jane M. Reid   +7 more
wiley   +1 more source

Genetic Association of Sexual Behavior, Sildenafil, and Hormonal Contraceptives With Mental Disorders. [PDF]

CNS Neurosci Ther
Lin Z, Zhu K, He R, Liu X, Luo Q, Wu H, Jiang Z, Yu J, Sheng J, Zhu H, Huang H.   +10 more
europepmc   +1 more source