Results 181 to 190 of about 133,969 (268)

Cardiovascular Health Was Moderate in Austrian Adolescents and Showed an Inverse Relationship With High‐Sensitivity C‐Reactive Protein Levels

Acta Paediatrica, EarlyView.
ABSTRACT Aim This Prospective, Community‐Based Cohort Study Investigated Cardiovascular Health and Its Association With Low‐Grade Inflammation in Adolescents. Methods Data were collected by specially trained medical staff from 1379 Austrian adolescents aged 14–19 years from 3 February 2021 to 28 February 2023.
Katharina Mueller, Alex Messner, Johannes Nairz, Ursula Kiechl‐Kohlendorfer, Michael Knoflach, Sophia Zollner‐Kiechl, Early Vascular Ageing in the Youth study group   +6 more
wiley   +1 more source

Causal Links Between Sleep Duration and Sarcopenia-Related Phenotypes: A Mendelian Randomization and Shared Genetic Mechanism Study. [PDF]

Am J Phys Med Rehabil
Shang H, Deng Z, Lian Y, Ai Y, Zhang J, Li G.   +5 more
europepmc   +1 more source

Growth and Variation in Fallow Deer (Dama dama L.) From Two Contrasting Habitats in Southern Britain

Acta Zoologica, EarlyView.
ABSTRACT We have compiled a unique data set on the age, sex, body weight and dimensions of over 500 European fallow deer from two contrasting areas of habitat in southern England: a high‐density managed parkland population and a lower‐density feral woodland one.
Adrian M. Lister, Norma G. Chapman
wiley   +1 more source

A 2-sample Mendelian randomization study exploring the causal effect of depression on rotator cuff injury. [PDF]

Medicine (Baltimore)
Hu C, Xiao Q, Mei JJ, Zhu JS.
europepmc   +1 more source

AMPK‐mediated prevention of vascular dysfunction with metformin: Experimental and population‐based evidence

British Journal of Pharmacology, EarlyView.
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi, Annika A. Jüttner, Annique Claringbould, Rene de Vries, Ingrid M. Garrelds, Usha Musterd‐Bhaggoe, Bruno H. Stricker, Maryam Kavousi, A. H. Jan Danser, Fariba Ahmadizar, Anton J. M. Roks   +10 more
wiley   +1 more source

Correction: Association of gut microbiota with lactose intolerance and coeliac disease: a two-sample Mendelian randomization study. [PDF]

Front Nutr
Han Z, Ran Y, Li J, Zhang X, Yang H, Liu J, Dong S, Jia H, Yang Z, Li Y, Guo L, Zhou S, Bao S, Yuan W, Wang B, Zhou L.   +15 more
europepmc   +1 more source

Discovery of PHB1 as a Novel Candidate Gene in Dominant Optic Atrophy

Clinical Genetics, EarlyView.
A heterozygous PHB1 missense variant (p.Ser147Phe) segregates with autosomal dominant optic atrophy in a multi‐generation family. Structural and cellular analyses suggest altered mitochondrial dynamics, identifying PHB1 as a novel candidate gene for hereditary optic neuropathy. ABSTRACT Hereditary optic neuropathies comprise a genetically heterogeneous
Marija Volk, Aleš Maver, Martina Jarc Vidmar, Nuša Trošt, Tanja Višnjar, Ana Fakin, Lea Kovač, Maja Šuštar Habjan, Lucija Malinar, Sanja Petrović Pajić, Urška Dragin Jerman, Rok Romih, Marko Hawlina, Borut Peterlin   +13 more
wiley   +1 more source

Genetically Determined Levels of Inflammation-Related Proteins and Functional Outcome After Ischemic Stroke: A Mendelian Randomization Study. [PDF]

J Stroke
Angerfors A, Andersson B, Furutjäll S, Chong M, Jern C, Stanne TM.   +5 more
europepmc   +1 more source

Novel Variants in PUS7 Associated With Intellectual Disability and Growth Retardation: Expanding the Clinical Spectrum in 13 Patients

Clinical Genetics, EarlyView.
Novel variants in PUS7 associated with intellectual disability and growth retardation: expanding the clinical spectrum in 13 patients. ABSTRACT Pseudouridylation is a frequent post‐transcriptional modification resulting in uridine isomerization in 5‐ribosyluracil, also called pseudouridine. This mechanism leads to RNA stability with an increase in base‐
Camille Bergès, Clément Sauvestre, Sophie Naudion, Catherine Vincent Delorme, Thomas Smol, Mélanie Rama, Stephanie Moortgat, Isabelle Maystadt, Rogier Kersseboom, Martina Wilke, Stefan Barakat, Yoann Vial, Laurence Perrin, Sandrine Passemard, Farooq Ahmad, Muhammad Umair, Tobias Haack, Mona Grimmel, Alma Kuechler, Anne Slavotinek, Patrick Devine, Ugur Hodoglugil, Faisal Zafar, Erum Afzal, Tracy Dudding‐Byth, Guillaume Jouret, Lucas Herissant, Stephanie Efthymiou, Henry Houlden, Marine Legendre, Vincent Michaud   +30 more
wiley   +1 more source

Mendelian Randomization to Examine the Causal Effects of Cystatin on Ovarian Lesions. [PDF]

Int J Womens Health
Yan T, Guo L, Lu R.
europepmc   +1 more source