Results 11 to 20 of about 236,698 (345)
Mendelian and Non-Mendelian Quadratic Operators [PDF]
In this paper, we attempt to provide mathematical models of Mendelian and Non-Mendelian inheritances of the bisexual population system having Fisher's {\textbf{1:1}} principle. In our model, we always assume that distributions of the same phenotype of female and male populations are equal. We study the evolution of a Mendelian trait.
Mansoor Saburov+2 more
arxiv +5 more sources
Celer: an Efficient Program for Genotype Elimination [PDF]
This paper presents an efficient program for checking Mendelian consistency in a pedigree. Since pedigrees may contain incomplete and/or erroneous information, geneticists need to pre-process them before performing linkage analysis.
Nicoletta De Francesco+2 more
doaj +2 more sources
The Interpretation of Mendelian Phenomena [PDF]
APROPOS of the discussion on the interpretation of Mendelian phenomena, may I seek enlightenment on one or two points from your readers? Mendelian phenomena are possible only when reproduction is bi-parental. They cannot occur, of course, when it is parthenogenetic.
G. ARCHDALL REID
+9 more sources
The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified ...
A Hodgkinson+29 more
arxiv +6 more sources
Glucosamine supplementation contributes to reducing the risk of type 2 diabetes: Evidence from Mendelian randomization combined with a meta-analysis. [PDF]
Objective Observational studies on glucosamine supplementation and type 2 diabetes risk have shown inconsistent results, necessitating the use of Mendelian randomization to clarify the true causal relationship.
Zhou S+5 more
europepmc +2 more sources
Does ankylosing spondylitis exert a bidirectional influence on hypertension? A two-sample Mendelian randomization study. [PDF]
Objective: Previous observational studies reported that ankylosing spondylitis is closely related to hypertension. However, it is still controversial whether the association between ankylosing spondylitis and hypertension is causal.
Hu W, Zhang K, Yang G, Wang H, Gao Y.
europepmc +2 more sources
Illustration of Mendelian Segregation [PDF]
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W. R. Ballard
openalex +5 more sources
Mendelian randomization (MR) is a term that applies to the use of genetic variation to address causal questions about how modifiable exposures influence different outcomes. The principles of MR are based on Mendel's laws of inheritance and instrumental variable estimation methods, which enable the inference of causal effects in the presence of ...
Eleanor Sanderson+10 more
openaire +4 more sources
Purpose: Observational research has indicated the presence of a causal relationship between sleep disturbances and low back pain (LBP). However, the link may have been biased by confounding factors.
Peng Shu+4 more
doaj +1 more source