Results 211 to 220 of about 236,698 (345)

APOE ɛ4 allele and TOMM40‐APOC1 variants jointly contribute to survival to older ages

Aging Cell, Volume 21, Issue 12, December 2022., 2022
The APOE ɛ4 allele and minor alleles of rs2075650 TOMM40 and rs12721046 APOC1 variants confer a higher risk of Alzheimer's disease compared with the ɛ4 allele and no minor alleles of these two polymorphisms. Here, we show that the same relationship characterizes chances to live 85 years and older. Nevertheless, we show that Alzheimer's disease does not
Alexander M. Kulminski, Ethan Jain‐Washburn, Ian Philipp, Liang He, Yury Loika, Elena Loiko, Olivia Bagley, Svetlana Ukraintseva, Anatoliy Yashin, Konstantin Arbeev, Eric Stallard, Mary F. Feitosa, Nicole Schupf, Kaare Christensen, Irina Culminskaya   +14 more
wiley   +1 more source

THE DIFFERENTIAL EFFECT OF RADIATIONS ON MENDELIAN PHENOTYPES OF THE GOLDFISH, CARASSIUS AURATUS

, 1939
H. B. Goodrich, John Philip Trinkaus
openalex   +2 more sources

Bidirectional Mendelian randomization reveals associations between telomere length and autoimmune diseases. [PDF]

Trials
Jiang Q, Yu C, Zhu S, Liu Y, Ye M.
europepmc   +1 more source

The longitudinal effects of neonatal anthropometry on attention problems in males and females

JCPP Advances, EarlyView.
Previous studies have demonstrated sex differences in the relationship between neonatal anthropometry and increased attention problems. Our study demonstrates that the nature of this relationship ‐ quadratic versus linear ‐ varies according to the anthropometric measure used and that the impact of increasing age on these effects differ in males and ...
Lars Meinertz Byg, Carol Wang, Jonathan J. Hirst, Roger Smith, Craig Pennell   +4 more
wiley   +1 more source

RNA-Mediated Non-Mendelian Inheritance in Mice: The Power of Memory. [PDF]

Biomolecules
Rassoulzadegan M.
europepmc   +1 more source

Exploring the association between systemic lupus erythematosus and osteonecrosis by Mendelian randomization analysis. [PDF]

Sci Rep
Qi B, Zhao J, Meng C, Bu P, Pu LQ, Zhao W, Li C, Xu Y.   +7 more
europepmc   +1 more source

Mendelian Characters among Shorthorns

, 1908
Karl Pearson
openalex   +1 more source

On Explaining Mendelian Phenomena [PDF]

, 1919
Loye Holmes Miller
openalex   +1 more source

Polygenic Risk Score Combined with Transcranial Sonography Refines Parkinson's Disease Risk Prediction

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dopaminergic neuron depletion in the substantia nigra (SN) and the pathological aggregation of α‐synuclein are the neuropathological hallmarks of Parkinson's disease (PD). Objectives This study aimed to investigate the association between the polygenic risk score for PD (PD‐PRS) and transcranial sonography (TCS)‐measured SN ...
Mart Kals, Anu Reigo, Maris Teder‐Laving, Mariliis Vaht, Estonian Biobank research team, Lili Milani, Reedik Mägi, Mari Nelis, Georgi Hudjašov, Tiit Nikopensius, Andres Metspalu, Toomas Toomsoo   +11 more
wiley   +1 more source

A Mendelian randomization study investigating the causal associations of 35 blood and urinary metabolite biomarkers with breast cancer development. [PDF]

Discov Oncol
Lin T, Liu Y, Liu Z, Liu A, Liu R, Wang Q.   +5 more
europepmc   +1 more source