Results 221 to 230 of about 271,662 (318)

The causal association between seven drugs and erectile dysfunction: a Mendelian randomization study

Zhan, Jian, Liu, Jing, Huang, Yilan, Jiang, Longyang   +3 more
openalex   +1 more source

Pathogenesis of Vitiligo: Integrating Immune and Non‐Immune Cell Crosstalk

The Journal of Dermatology, EarlyView.
ABSTRACT Vitiligo is an acquired autoimmune disease characterized by depigmented macules resulting from melanocyte loss. It is a complex multifactorial disorder in which genetic predisposition is combined with environmental factors; however, its detailed etiology remains unclear.
Shintaro Inoue
wiley   +1 more source

Identifying Therapeutic Targets for Bronchial Asthma: Systematic Druggable Genome-Wide Mendelian Randomization. [PDF]

Health Sci Rep
Wang H, Zhang P, Yu H, Shi L, Wang T.
europepmc   +1 more source

Implications of uniparental disomy in forensic kinship testing: A case study of paternal isodisomy on chromosome 3

Journal of Forensic Sciences, EarlyView.
Abstract In typical inheritance, a child receives one chromosome of each pair from each parent. In rare cases, however, both chromosomes may be inherited from the same parent, a phenomenon known as uniparental disomy (UPD). In forensic kinship testing, UPD can lead to Mendelian inconsistencies between parent and child, increasing the risk of ...
Hannah Fontanil, Sharlize Pedroza Matute, Thomas Haizel, Sasitaran Iyavoo   +3 more
wiley   +1 more source

Causal association between blood immune cells and chronic hepatitis B: Univariable and multivariable Mendelian randomization. [PDF]

Medicine (Baltimore)
Dong J, Peng Z, Qin C, Shi T.
europepmc   +1 more source

Genetic engineering for SIT application: a fruit fly‐focused review

Insect Science, EarlyView.
Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova, Danheng Yu, Angela Meccariello   +2 more
wiley   +1 more source

Lifestyle behaviors, serum metabolites and high myopia: Mendelian randomization and mediation analysis. [PDF]

Int J Ophthalmol
Liu NE, Xu XT, Yu XB.
europepmc   +1 more source

Functional validation of a white pupae minimal gene construct in Ceratitis capitata (Diptera: Tephritidae)

Insect Science, EarlyView.
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates, Roswitha A. Aumann, Inga Sievers, Tanja Rehling, Marc F. Schetelig   +4 more
wiley   +1 more source

Causal relationships between blood metabolites and glioblastoma risk: a large-scale Mendelian randomization study. [PDF]

Discov Oncol
Huang L, Tang Y, Tan Y, Lei W, Wang Y, Luo Y.   +5 more
europepmc   +1 more source

Cathepsins and cancer risk: a Mendelian randomization study [PDF]

Tingting Deng, Xixue Lu, Xuemin Jia, Jinxin Du, Lijuan Wang, Baorui Cao, Meina Yang, Ying Yin, Fanjie Liu   +8 more
openalex   +1 more source