Results 181 to 190 of about 51,589 (295)

Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

, 2014
Petroula Proitsi, Michelle K. Lupton, Latha Velayudhan, Stephen Newhouse, Isabella Fogh, Magda Tsolaki, Makrina Daniilidou, Megan Pritchard, Iwona Kłoszewska, Hilkka Soininen, Patrizia Mecocci, Bruno Vellas, Julie Williams, Robert Stewart, Pak C. Sham, Simon Lovestone, John Powell   +16 more
openalex   +2 more sources

Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study [PDF]

, 2016
Suzanne C. Dixon‐Suen, Christina M. Nagle, Aaron P. Thrift, Paul D.P. Pharoah, Celeste Leigh Pearce, Wei Zheng, Jodie N. Painter, Georgia Chenevix‐Trench, Peter A. Fasching, Matthias W. Beckmann, Diether Lambrechts, Ignace Vergote, Sandrina Lambrechts, Els Van Nieuwenhuysen, Mary Anne Rossing, Jennifer A. Doherty, Kristine G. Wicklund, Jenny Chang‐Claude, Anja Rudolph, Kirsten B. Moysich, Kunle Odunsi, Marc T. Goodman, Lynne R. Wilkens, Pamela J. Thompson, Yurii B. Shvetsov, Thilo Dörk, Tjoung‐Won Park‐Simon, Peter Hillemanns, Natalia Bogdanova, Ralf Bützow, Heli Nevanlinna, Liisa M. Pelttari, Arto Leminen, Francesmary Modugno, Roberta B. Ness, Robert P. Edwards, Joseph L. Kelley, Florian Heitz, Beth Y. Karlan, Susanne K. Kjær, Estrid Høgdall, Allan Jensen, Ellen L. Goode, Brooke L. Fridley, Julie M. Cunningham, Stacey J. Winham, Graham G. Giles, Fiona Bruinsma, Roger L. Milne, Melissa C. Southey, Michelle A.T. Hildebrandt, Xifeng Wu, Karen H. Lu, Dong Liang, Douglas A. Levine, Maria Bisogna, Joellen M. Schildkraut, Andrew Berchuck, Daniel W. Cramer, Kathryn L. Terry, Elisa V. Bandera, Sara H. Olson, Helga B. Salvesen, Liv Cecilie Vestrheim Thomsen, Reidun Kristin Kopperud, Line Bjørge, Lambertus A. Kiemeney, Leon F.A.G. Massuger, Tanja Pejović, Linda S. Cook, Nhu D. Le, Kenneth D. Swenerton, Angela Brooks‐Wilson, Linda E. Kelemen, Jan Lubiński, Tomasz Huzarski, Jacek Gronwald, Janusz Menkiszak, Nicolas Wentzensen, Louise A. Brinton, Hannah Yang, Jolanta Lissowska, Claus Høgdall, Lene Lundvall, Honglin Song, Jonathan P. Tyrer, Ian Campbell, Diana Eccles, James Paul, Rosalind Glasspool, Nadeem Siddiqui, Alice S. Whittemore, Weiva Sieh, Valerie McGuire, Joseph H. Rothstein, Steven A. Narod, Catherine Phelan, Harvey A. Risch, Esther M. John, Hoda Anton‐Culver   +99 more
openalex   +1 more source

Commentary: Mendelian randomization and women’s health [PDF]

International Journal of Epidemiology, 2019
Censin, JC, Bovijn, J, Holmes, MV, Lindgren, CM   +3 more
openaire   +3 more sources

The Effect of Immediate Skin‐to‐Skin Contact on Exclusive Breastfeeding: An Instrumental Variable Approach

Acta Paediatrica, EarlyView.
ABSTRACT Aim Given the significant decline in exclusive breastfeeding rates in the Republic of Korea, this study aimed to estimate the causal effect of immediate skin‐to‐skin contact on exclusive breastfeeding. Methods Data were analysed from the Korean Early Childhood Education & Care Panel, targeting mothers expected to give birth in 2022 in the ...
Sangyun Lee, Yongnam Kim
wiley   +1 more source

Association Between Dysmenorrhea and Endometrial Cancer: A Mendelian Randomization Study. [PDF]

Pain Res Manag
Huang Q, Huang X, Huang L, Wang Y, Li S, Zheng X.   +5 more
europepmc   +1 more source

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye, Claire Pearson, Tibyan Babiker, Emilio Agostinelli, Rumaitha Al‐Hosni, Paolo Tammaro   +5 more
wiley   +1 more source

Research progress of Mendelian randomization analysis for glaucoma etiology. [PDF]

Int J Ophthalmol
Wang JM, Song YW, Su JJ, Fu LC, Gong D, Guo P, Yang WH.   +6 more
europepmc   +1 more source

Commentary: Two-sample Mendelian randomization: opportunities and challenges [PDF]

, 2016
Debbie A. Lawlor
openalex   +1 more source

Targeting FABP4 to Inhibit AGEs‐RAGE/NF‐κB Signalling Effectively Ameliorates Nucleus Pulposus Dysfunction and Angiogenesis in Obesity‐Related Intervertebral Disc Degeneration

Cell Proliferation, EarlyView.
Obesity promotes the progression of intervertebral disc degeneration (IVDD) through the mTORC1/FABP4 axis. Targeting FABP4 effectively ameliorates nucleus pulposus dysfunction and angiogenesis in obesity‐related IVDD. ABSTRACT Intervertebral disc degeneration (IVDD) is a primary contributor to low back pain, posing significant social and economic ...
Lin Han, Fudong Li, Huiqiao Wu, Weiheng Wang, Peiwen Chen, Weicheng Xia, Yang Liu, Kaiqiang Sun, Wenbo Lin   +8 more
wiley   +1 more source

Dietary factors and risk for endometriosis: a Mendelian randomization analysis. [PDF]

Nutr Metab (Lond)
Zhang X, Zheng Q, Chen L.
europepmc   +1 more source