Results 191 to 200 of about 60,478 (247)

Multiomics: Two-Sample, Bidirectional, Multivariate and Mediated Mendelian Randomization Analysis of Allergic Rhinitis [PDF]

Cheng Zhong, Lihua Wang, Hao-peng Zhang, Lin Ji, Yu Guo   +4 more
openalex   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Causal role of immunophenotypes in hepatocellular carcinoma: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Ou D, Huo J.
europepmc   +1 more source

RETRACTION: Causal Effects of Genetically Determined Metabolites on Androgenetic Alopecia: A Two‐Sample Mendelian Randomization Analysis [PDF]

openalex   +1 more source

A Principled Framework for Mendelian Randomization in Oral Health Research

Journal of Periodontal Research, EarlyView.
This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir, Mario Romandini, Moritz Kebschull, Konstantinos K. Tsilidis, Dominique S. Michaud, Stephen Burgess   +5 more
wiley   +1 more source

The role of estimation in Mendelian randomization: should Mendelian randomization investigations provide estimates? [PDF]

AJE Adv
Woolf B, Burgess S.
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Lifestyle behaviors, serum metabolites and high myopia: Mendelian randomization and mediation analysis. [PDF]

Int J Ophthalmol
Liu NE, Xu XT, Yu XB.
europepmc   +1 more source