Results 191 to 200 of about 72,268 (331)

Functional validation of a white pupae minimal gene construct in Ceratitis capitata (Diptera: Tephritidae)

Insect Science, EarlyView.
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates, Roswitha A. Aumann, Inga Sievers, Tanja Rehling, Marc F. Schetelig   +4 more
wiley   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, EarlyView.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source

BioWinfordMR: an online platform for comprehensive Mendelian randomization analysis. [PDF]

Front Immunol
Wang Y, Wu T, Lu X, Wang X, Xue W.
europepmc   +1 more source

No association between celiac disease and female infertility: evidence from Mendelian randomization analysis [PDF]

Shuai Yuan, Jie Chen, Xue Li, Daniel A. Leffler, Susanna C. Larsson, Jonas F. Ludvigsson   +5 more
openalex   +1 more source

Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases

, 2022
huiling zhao, jie zheng
openalex   +2 more sources

Causal relationship between immune cells and idiopathic thrombocytopenic purpura: A bidirectional Mendelian randomization study

Rheumatology &Autoimmunity, EarlyView.
Heyi Zhang, Luyao Song, Ying Mao, Zerui Liu, Zhexi He, Mengxia Liu, Jingfang Zhang, Rui Zhao, Jing Luo, Shengxiao Zhang   +9 more
wiley   +1 more source

Adolescent cannabis use and psychological distress from 2013 to 2023: A population‐based study in Ontario, Canada

Addiction, EarlyView.
Abstract Background and aims Epidemiologic research suggests that adolescent cannabis use is associated with psychological distress (i.e. depression and anxiety symptoms); however, most studies have relied on 20th‐century data, when cannabis was significantly less potent than today.
André J. McDonald, Amanda Doggett, Susan J. Bondy, Ian Colman, Steven Cook, Hayley A. Hamilton, Paul Kurdyak, Scott T. Leatherdale, Daniel T. Myran, Jürgen Rehm, Christine M. Wickens, James MacKillop, Jillian Halladay   +12 more
wiley   +1 more source

Association between asthma and myopia: the NHANES database and Mendelian randomization analysis. [PDF]

Int J Ophthalmol
Zheng YJ, Kuang JF, Chen FL, Huang WB.
europepmc   +1 more source

Toenail and blood selenium mediated regulation of thyroid dysfunction through immune cells: a mediation Mendelian randomization analysis [PDF]

Yu-jia Jiang, Yiquan Xiong, Tao Huang, Yun-xiao Xiao   +3 more
openalex   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source