Results 221 to 230 of about 72,268 (331)

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Robust Diagnostic and Therapeutic Biomarkers for Tuberculosis Identified Through Multi-Omics and Mendelian Randomization Analysis. [PDF]

MedComm (2020)
Zhu C, Chen J, Li Y, Zhang Q, Lu Q, Zhang N, Fan H, Khakwani MMAK, Zhang L, Li JC.   +9 more
europepmc   +1 more source

Lifestyle risk factors and stroke: findings from the national health and nutrition examination survey (1999–2020) and a Mendelian randomization analysis

Xiaomin Feng, Zhangping He, Qin Zhu, Jing Lü, Chao Qin, Yanyan Tang   +5 more
openalex   +1 more source

Genomic Prediction Ability for Novel Profitability Traits Using Different Models in Nelore Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The aim of this study was to assess the accuracy, bias and dispersion of genomic predictions for accumulated profitability (APF) and profit per kilogram of liveweight gain (PFT) in Nelore cattle using different prediction approaches. The dataset consisted of 3969 phenotypic records for each trait. The pedigree harboured information from 38,930
Letícia Silva Pereira, Cláudio Ulhôa Magnabosco, Guilherme Rosa, Nedenia Bonvino Stafuzza, Tiago Zanett Albertini, Minos Carvalho, Raysildo Barbosa Lobo, Elisa Peripolli, Eduardo da Costa Eifert, Fernando Baldi   +9 more
wiley   +1 more source

Plasma proteins and rheumatoid arthritis: A Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Lu C, Huang XX, Lu X, Huang M, Xu J.
europepmc   +1 more source

Single‐Step Genomic Predictions for Growth and Carcass Traits in Nordic Charolais and Hereford Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In order to investigate the applicability and efficiency of genomic selection for growth and carcass traits in Nordic beef cattle, single‐step genomic BLUP (ssGBLUP) was applied in 4321 Charolais and 4532 Hereford animals with information on approximately 43,000 SNPs each.
Anahit Nazari‐Ghadikolaei, Freddy Fikse, Susanne Eriksson   +2 more
wiley   +1 more source

Lung cancer and COVID-19 susceptibility and severity: a Mendelian randomization analysis. [PDF]

BMC Cancer
Bai M, Li J.
europepmc   +1 more source

Genomic Prediction and Genome‐Wide Association Analysis of Heat Tolerance for Milk Yield in Buffaloes Using a Reaction Norm Model

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The aim of this study was to evaluate the impact of incorporating genomic information on the estimation of genetic (co)variance components and the accuracy of breeding values for milk yield under varying thermal environments, and to identify SNPs associated with genes that play significant roles in heat tolerance.
Gabriela Stefani, Mário Luiz Santana, Lenira El Faro, Humberto Tonhati   +3 more
wiley   +1 more source

Investigating the Impact of Gut Microbiota on Gout Through Mendelian Randomization

Orthopedic Research and Reviews
Chaoqun Tang,1 Lei Li,2 Xin Jin,2 Jinfeng Wang,2 Debao Zou,2 Yan Hou,2 Xin Yu,2 Zhizhou Wang,2 Hongjiang Jiang1,2 1The First Clinical Medical School, Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2Department of ...
Tang C, Li L, Jin X, Wang J, Zou D, Hou Y, Yu X, Wang Z, Jiang H   +8 more
doaj  

Figure 3 from Identification of Causal Plasma Proteins in Hepatocellular Carcinoma via Two-Sample Mendelian Randomization and Integrative Transcriptomic‒Proteomic Analysis

Weihao Tang, Xiaoke Ma
openalex   +1 more source