Results 251 to 260 of about 1,141,533 (358)

Estimates of the effects of physical activity on osteoporosis using multivariable Mendelian randomization analysis

, 2021
Fang Xu, Q. Zhang, Liu Wang, Qi-Xin Tang, Changqing Sun, Hong-Wen Deng   +5 more
openalex   +2 more sources

Obesity drives the link between liver fat and depression: Cross‐sectional and prospective investigations

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Inconsistent associations have been reported between steatotic liver disease (SLD) and depression. We aimed to investigate the cross‐sectional and prospective associations between MRI‐derived liver fat, SLD and depression. Materials and Methods We used UK Biobank data. Liver fat was measured with liver MRI proton density fat fraction. SLD
Qi Feng, Chioma N. Izzi‐Engbeaya, Pinelopi Manousou, Mark Woodward   +3 more
wiley   +1 more source

A Mendelian randomization analysis reveals the role of the skin microbiota in systemic lupus erythematosus. [PDF]

Clin Rheumatol
Yin Y, Zhao J, Tao Z, Wang J.
europepmc   +1 more source

Exploring population and sex‐specific disease trajectories for multimorbidities among individuals with overweight or obesity: A retrospective cohort study in UK biobank

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Background Overweight and obesity are major risk factors for non‐communicable diseases (NCDs). This study aimed to explore the pattern of multimorbidity development and disease trajectories in individuals with overweight and obesity. Methods We followed a cohort of 392 541 individuals retrospectively from the UK Biobank.
Qianhui Lu, Yining Bao, Fang Lu, Priya Sumithran, Terence J. O'Brien, Qiuhong Yue, Runxin Li, Yilan Lv, Chongjian Wang, Lei Zhang   +9 more
wiley   +1 more source

Bidirectional Mendelian randomization analysis of inflammatory factors and sleep related traits. [PDF]

Brain Behav Immun Health
Liao Z, Guo S, Wang K, Xu Y, Zheng R, Yu B, Zhao G, Zhang R, Kang X, Ai S.   +9 more
europepmc   +1 more source

Adherence to four dietary indices and the risk of all‐cause and cause‐specific dementia: Findings from the UK Biobank study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Despite several modifiable risk factors for dementia being identified, diet is often excluded from consideration due to insufficient evidence. Although various healthy dietary indices have been associated with improved health outcomes, their link to dementia risk remains unclear.
Fernanda Carrasco‐Marín, Solange Parra‐Soto, Marion Guerrero‐Wyss, Carolina Araya‐Bastias, Jirapitcha Boonpor, Carla Villagrán‐Cerro, Fanny Petermann‐Rocha, Oliver M. Shannon, John C. Mathers, Katherine M. Livingstone, Sara Dingle, Sofía Gálvez‐Tejeda, Ana Hernández‐Peregrina, Nishka Pranay, Guillermo Molina‐Recio, Jill Pell, Frederick Ho, Carlos Celis‐Morales, Rafael Molina‐Luque   +18 more
wiley   +1 more source

The Effects of Specific Gut Microbiota on Hyperuricemia - A Mendelian Randomization Analysis and Clinical Validation. [PDF]

Diabetes Metab Syndr Obes
Αikepa D, He Y, Chen W, Liang M, Du Y, Chen X, Du M, Zhu Y, Wang J, Sun Y.   +9 more
europepmc   +1 more source

N‐lactoyl amino acids are potential biomarkers for insulin resistance and diabetic complications

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims N‐lactoyl amino acids (Lac‐AA) are emerging as crucial players in metabolic research, with potential implications for disease mechanisms and therapeutic interventions. This study exploress the role of Lac‐AA in insulin resistance, type 2 diabetes (T2D), and its complications.
Khaled Naja, Asma A. Elashi, Najeha Anwardeen, Aleem Razzaq, Laila Hedaya, Shamma Almuraikhy, Ilhame Diboun, Karsten Suhre, Omar AlBagha, Mohamed A. Elrayess   +9 more
wiley   +1 more source

Causal relationship between gastroesophageal reflux disease and IgA nephropathy: a Mendelian randomization analysis. [PDF]

Ren Fail
Han Q, Duan Y, Jin M, Ma L, Zhao X, Ren Q, Chen F, Ding X, Du J, Song C, Xu K, Zhu H, Sun Q.   +12 more
europepmc   +1 more source

Clinical whole genome sequencing in pediatric epilepsy: Genetic and phenotypic spectrum of 733 individuals

Epilepsia, EarlyView.
Abstract Objective A large proportion of pediatric epilepsies have an underlying genetic etiology. Limited studies have explored the efficacy of whole genome sequencing (WGS) in a clinical setting. Our academic–clinical center implemented clinical whole exome sequencing (WES) in 2014, then transitioned to WGS from 2015.
Olivia J. Henry, Sofia Ygberg, Michela Barbaro, Nicole Lesko, Leif Karlsson, Lucía Peña‐Pérez, Ann Båvner, Virpi Töhönen, Anna Lindstrand, Tommy Stödberg, Anna Wedell   +10 more
wiley   +1 more source