Results 171 to 180 of about 8,221 (187)

Impaired meningeal lymphatic vessels exacerbate early brain injury after experimental subarachnoid hemorrhage

Brain Research, 2021
Blood that enters the subarachnoid space (SAS) and its breakdown products are neurotoxic and are the principal inducers of brain injury after subarachnoid hemorrhage (SAH). Recently, meningeal lymphatic vessels (MLVs) have been proven to play an important role in clearing erythrocytes that arise from SAH, as well as other macromolecular solutes ...
Yan Zhao, Bangyue Wang, Jian Li, Weihan Wang, Hao Zhang, Xinyu Yang, Xinyu Yang, Changkai Hou, Quanlei Liu, Cong Fu   +9 more
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Emerging Roles of Meningeal Lymphatic Vessels in Ischemic Stroke

Molecular Neurobiology
This review highlights the emerging relevance of meningeal lymphatic vessels (MLVs) in the context of ischemic stroke, challenging the conventional view of a privileged immunological central nervous system. MLVs facilitate immunological surveillance by modulating the entry of peripheral immune cells into the meningeal compartment, a process not impeded
Richard Simon Machado, Khiany Mathias, Larissa Joaquim, Maiara de Aguiar da Costa, Anita Dal Bó Tiscoski, Cinara Ludvig Gonçalves, Gislaine Tezza Rezin, Fabrícia Petronilho   +7 more
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A deeper dive into amyloid clearance by meningeal lymphatic vessels

Nature Cardiovascular Research
Monica M. Santisteban, Costantino Iadecola   +1 more
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The Drainage Dysfunction of Meningeal Lymphatic Vessels Is Correlated with the Recurrence of Chronic Subdural Hematoma: a Prospective Study

Translational Stroke Research, 2023
Meningeal lymphatic vessels (mLVs) were recently discovered to be involved in the waste drainage process in the brain, which has also been associated with a variety of neurological diseases. This research paper hypothesizes that the drainage function of mLVs may be affected after chronic subdural hematoma (CSDH) and the alterations of mLVs' drainage ...
Jiahao Zhang, Lei Yu, Xiaoyu Wang, Qian Yu, Bingrui Zhu, Haocheng Zhang, Yibo Liu, Huaming Li, Anke Zhang, Kaikai Wang, Yezhao He, Qun Wu, Yuanjian Fang, Jianzhong Sun, Sheng Chen   +14 more
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Improving the Function of Meningeal Lymphatic Vessels to Promote Brain Edema Absorption after Traumatic Brain Injury

Journal of Neurotrauma, 2023
Brain edema is the most common and fatal complication after traumatic brain injury (TBI). Meningeal lymphatic vessels (MLVs) are the conduits that transport cerebrospinal fluid (CSF) and macromolecules to deep extracranial cervical lymph nodes (dCLNs). After TBI, the drainage function of MLVs can become impaired.
Jianwen, Liao, Mingchao, Zhang, Zichuan, Shi, Hao, Lu, Lichen, Wang, Weijia, Fan, Xiaoguang, Tong, Hua, Yan   +7 more
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Advances in Research on Meningeal Lymphatic Vessels in Central Nervous System Diseases

Journal of Craniofacial Surgery
Meningeal lymphatic vessels (mLVs), located around the dural sinuses, are considered significant participants in cerebrospinal fluid (CSF) circulation. Meningeal lymphatic vessels not only drain fluids and metabolic waste from the brain into deep cervical lymph nodes (dCLNs) but also transport immune cells from the brain to dCLNs, thus regulating the ...
Huimin, Shen, Bingrui, Zhu, Yajun, Qian, Jiancheng, Jin, Jiankuai, Zhou, Guotao, Peng, Jun, Mo   +6 more
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Photo-modulation and monitoring of meningeal lymphatic vessels

Biophotonics and Immune Responses XX
Zhenping Xu, Xi Li, Miao Wang, Feifan Zhou   +3 more
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Dynamics of Evans blue clearance from cerebrospinal fluid into meningeal lymphatic vessels and deep cervical lymph nodes

Neurological Research, 2018
Objectives Recently, it has been confirmed, that excess fluid and waste products from the brain are drained into the cerebrospinal fluid (CSF) and afterwards cleared via the olfactory route and/or lymphatic vessels in the brain dura and corresponding extracranial lymphatic structures.
Eva Petrovova, Andrej Kovac, Lenka Kresakova, Katarina Vdoviakova, Veronika Cubinkova, Jan Danko, Dasa Cizkova, Marcela Maloveska, Alena Michalicova   +8 more
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Vitamin D accelerates the subdural hematoma clearance through improving the meningeal lymphatic vessel function

Molecular and Cellular Biochemistry
Subdural hematoma (SDH) drains into the extracranial lymphatic system through the meningeal lymphatic vessels (mLVs) but the formation of SDH impairs mLVs. Because vitamin D (Vit D) can protect the endothelial cells, we hypothesized that Vit D may enhance the SDH clearance.
Yupeng, Chen, Xuanhui, Liu, Jiangyuan, Yuan, Shiying, Dong, Meng, Nie, Weiwei, Jiang, Di, Wu, Mingqi, Liu, Tao, Liu, Chenrui, Wu, Chuang, Gao, Jianning, Zhang, Rongcai, Jiang   +12 more
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Image Analysis for Describing Meningeal Lymphatic Vessel Morphology

2020
Neuroscientists have recently discovered the existence of meningeal lymphatic vessels in the brain and have shown their importance in preventing cognitive decline. With age, lymphatic vessels narrow, poorly draining cerebrospinal and interstitial fluids, which leads to plaque accumulation, a hallmark of Alzheimer’s disease.
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