Results 11 to 20 of about 141,509 (350)

The polo-like kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia [PDF]

open access: yes, 2013
CD56 is expressed in 15–20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis.
A Blair   +55 more
core   +10 more sources

Anterior Clinoidal Meningiomas: Meningeal Anatomical Considerations and Surgical Implications

open access: yesFrontiers in Oncology, 2020
Objective: Surgical removal of anterior clinoidal meningiomas (ACMs) remains a challenge because of its complicated relationship with surrounding meninges, major arteries and cranial nerves.
Tao Xu   +11 more
doaj   +1 more source

Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges

open access: yesCells, 2021
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
doaj   +1 more source

Carcinomatose das meninges

open access: yesArquivos de Neuro-Psiquiatria, 1959
Registro de um caso de carcinomatose das leptomeninges secundária a carcinoma sólido do estômago. Células carcinomatosas foram encontradas no liqüido cefalorraquidiano colhido tanto por via suboccipital como no ventrículo lateral. O exame histopatológico
Oswaldo Ricciardi Cruz
doaj   +1 more source

Appearance of the canine meninges in subtraction magnetic resonance images [PDF]

open access: yes, 2014
The canine meninges are not visible as discrete structures in noncontrast magnetic resonance (MR) images, and are incompletely visualized in T1‐weighted, postgadolinium images, reportedly appearing as short, thin curvilinear segments with minimal ...
Frean, S P   +3 more
core   +1 more source

Translationally Relevant Magnetic Resonance Imaging Markers in a Ferret Model of Closed Head Injury

open access: yesFrontiers in Neuroscience, 2022
Pre-clinical models of traumatic brain injury (TBI) have been the primary experimental tool for understanding the potential mechanisms and cellular alterations that follow brain injury, but the human relevance and translational value of these models are ...
Elizabeth B. Hutchinson   +18 more
doaj   +1 more source

Meningitis [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1984
Publisher Summary This chapter describes the clinical aspects of meningitis. In most patients who prove to have meningitis, the need for lumbar puncture is evident on first assessment. Meningeal signs are often found in patients with pneumonia or with acute tonsillitis, in patients generally with high fever, and occasionally in certain specific ...
openaire   +3 more sources

Preliminary study on double ⁃ dose icotinib successfully treated leptomeningeal metastasis in lung adenocarcinoma patient with EGFR gene sensitive mutation

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To report the diagnosis and treatment of a patient with meningeal metastases from lung adenocarcinoma, and explore the significance of cerebrospinal fluid (CSF) gene detection for clinical treatment and the efficacy and safety of double⁃dose ...
LIU Mei   +5 more
doaj   +1 more source

Tertiary lymphoid organs in central nervous system autoimmunity [PDF]

open access: yes, 2016
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
core   +1 more source

High Yield of Adult Oligodendrocyte Lineage Cells Obtained from Meningeal Biopsy

open access: yesFrontiers in Pharmacology, 2017
Oligodendrocyte loss can lead to cognitive and motor deficits. Current remyelinating therapeutic strategies imply either modulation of endogenous oligodendrocyte precursors or transplantation of in vitro expanded oligodendrocytes.
Sissi Dolci   +15 more
doaj   +1 more source

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