Results 21 to 30 of about 145,378 (351)

Cholinergic Nociceptive Mechanisms in Rat Meninges and Trigeminal Ganglia: Potential Implications for Migraine Pain

open access: yesFrontiers in Neurology, 2017
BackgroundParasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches.
Rashid Giniatullin   +9 more
doaj   +1 more source

Brain tumors induced in rats by human adenovirus type 12 [PDF]

open access: yes, 1974
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu strains were injected intracranially with human adenovirus type 12. The incidence of intracranial tumors was 91% (30/33) in
Matsuo, Keisuke   +5 more
core   +1 more source

Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons [PDF]

open access: yes, 2017
The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders.
Alhouayek M   +183 more
core   +1 more source

A neoplasm associated with the meninges of the spinal canal – a case report

open access: yesJournal of Education, Health and Sport, 2019
Introduction: Spinal canal neoplasms are a heterogeneous group of diseases including both primary and metastatic tumors, either benign or malignant. These tumors can develop both intraspinally and peripherally.
Marcin Kulczyński   +3 more
doaj   +3 more sources

TRP Channels and Migraine: Recent Developments and New Therapeutic Opportunities

open access: yesPharmaceuticals, 2019
Migraine is the second-most disabling disease worldwide, and the second most common neurological disorder. Attacks can last many hours or days, and consist of multiple symptoms including headache, nausea, vomiting, hypersensitivity to stimuli such as ...
Silvia Benemei, Greg Dussor
doaj   +1 more source

Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System

open access: yesFrontiers in Immunology, 2021
The central nervous system (CNS) parenchyma is enclosed and protected by a multilayered system of cellular and acellular barriers, functionally separating glia and neurons from peripheral circulation and blood-borne immune cells. Populating these borders
Daniela C. Ivan   +4 more
doaj   +1 more source

CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS [PDF]

open access: yes, 2017
No abstract ...
A de Lourdes Perim   +14 more
core   +1 more source

Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges

open access: yesCells, 2021
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
doaj   +1 more source

Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis [PDF]

open access: yes, 2017
Although Trypanosoma brucei spp. was first detected by Aldo Castellani in CSF samples taken from sleeping sickness patients over a century ago there is still a great deal of debate surrounding the timing, route and effects of transmigration of the ...
Bradley, Barbara   +2 more
core   +1 more source

Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice

open access: yeseLife, 2021
Peripheral nerve injury-induced neuropathic pain is a chronic and debilitating condition characterized by mechanical hypersensitivity. We previously identified microglial activation via release of colony-stimulating factor 1 (CSF1) from injured sensory ...
Julia A Kuhn   +10 more
doaj   +1 more source

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