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BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus
Stem Cell Reports, 2017 BACE1 is validated as Alzheimer's β-secretase and a therapeutic target for Alzheimer's disease. In examining BACE1-null mice, we discovered that BACE1 deficiency develops abnormal clusters of immature neurons, forming doublecortin-positive neuroblasts ...
Hailong Hou +5 more
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Mechanical Characterization and Modeling of the Porcine Cerebral Meninges
Frontiers in Bioengineering and Biotechnology, 2020 The cerebral meninges, made up of the dura, arachnoid, and pia mater, is a tri-layer membrane that surrounds the brain and the spinal cord and has an important function in protecting the brain from injury.
Baptiste Pierrat +10 more
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Necrotizing meningoencephalitis in atypical dog breeds: a case series and literature review. [PDF]
, 2014 BackgroundCanine necrotizing meningoencephalitis (NME) is a fatal, noninfectious inflammatory disease of unknown etiology. NME has been reported only in a small number of dog breeds, which has led to the presumption that it is a breed-restricted disorder.
Cooper, JJ +7 more
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Dural Immune Cells, CGRP, and Migraine
Frontiers in Neurology, 2022 Migraine is the most common neurological disorder in the world, affecting 12% of the population. Migraine involves the central nervous system, trigeminal nerves and meninges. Recent advances have shown that targeting calcitonin gene-related peptide (CGRP)
Louis K. Balcziak +4 more
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The avian tectobulbar tract: development, explant culture, and effects of antibodies on the pattern of neurite outgrowth [PDF]
, 1990 The tectobulbar tract is the first long-distance projecting fiber pathway to appear during the development of the avian optic tectum (dorsal half of the mesencephalon).
Kröger, Stephan, Schwarz, U.
core +2 more sources
Nanomaterials, 2014 Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre ...
Iraklis Papageorgiou +5 more
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Case Report: Primary Diffuse Leptomeningeal Oligodendrogliomatosis in a Young Adult Cat
Frontiers in Veterinary Science, 2021 A 2-year-old cat was presented with progressive ataxia. Despite treatment the animal died. Pathomorphological examination revealed a widespread leptomeningeal mass at all levels of the central nervous system accentuated on the cervical spinal cord and ...
Elisa Chludzinski +3 more
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Pathomorphosis of Extrapulmonary Tuberculosis in Children [PDF]
, 2016 Aim. To study clinical and epidemiological aspects of pathomorphosis of extrapulmonary tuberculosis clinical forms.Materials and Methods. Retrospective analysis of 138 case histories in children aged to 15 years, obtaining extrapulmonary tuberculosis ...
Mykolyshyn, L. (Lidia) +1 more
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Through Skull Fluorescence Imaging of the Brain in a New Near-Infrared Window [PDF]
, 2014 To date, brain imaging has largely relied on X-ray computed tomography and magnetic resonance angiography with limited spatial resolution and long scanning times.
Andreasson, Katrin I. +11 more
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Entry, dispersion and differentiation of microglia in the developing central nervous system
Anais da Academia Brasileira de Ciências, 2000 Microglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream.
JULIO NAVASCUÉS +3 more
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