Results 51 to 60 of about 141,509 (350)

Through Skull Fluorescence Imaging of the Brain in a New Near-Infrared Window [PDF]

open access: yes, 2014
To date, brain imaging has largely relied on X-ray computed tomography and magnetic resonance angiography with limited spatial resolution and long scanning times.
Andreasson, Katrin I.   +11 more
core   +4 more sources

Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice

open access: yeseLife, 2021
Peripheral nerve injury-induced neuropathic pain is a chronic and debilitating condition characterized by mechanical hypersensitivity. We previously identified microglial activation via release of colony-stimulating factor 1 (CSF1) from injured sensory ...
Julia A Kuhn   +10 more
doaj   +1 more source

Bacterial meningitis and tuberculous meningitis. [PDF]

open access: yesBMJ, 1973
Despite the wide range of antimicrobial drugs available to day the mortality and morbidity from bacterial meningitis is disappointingly high. This disappointment is all the more poignant when one appreciates that some 75% of pyogenic meningitis in Britain results from infection by one of three organisms?namely, Neisseria meningitidis, Streptococcus ...
openaire   +3 more sources

Necrotizing meningoencephalitis in atypical dog breeds: a case series and literature review. [PDF]

open access: yes, 2014
BackgroundCanine necrotizing meningoencephalitis (NME) is a fatal, noninfectious inflammatory disease of unknown etiology. NME has been reported only in a small number of dog breeds, which has led to the presumption that it is a breed-restricted disorder.
Cooper, JJ   +7 more
core   +1 more source

Biological Effects of Clinically Relevant CoCr Nanoparticles in the Dura Mater: An Organ Culture Study

open access: yesNanomaterials, 2014
Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre ...
Iraklis Papageorgiou   +5 more
doaj   +1 more source

Live imaging of microglia during sleeping sickness reveals early and heterogeneous inflammatory responses

open access: yesFrontiers in Immunology, 2023
IntroductionInvasion of the central nervous system (CNS) is the most serious consequence of Trypanosoma brucei infection, which causes sleeping sickness.
Nestor L. Uzcategui   +9 more
doaj   +1 more source

Entry, dispersion and differentiation of microglia in the developing central nervous system

open access: yesAnais da Academia Brasileira de Ciências, 2000
Microglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream.
JULIO NAVASCUÉS   +3 more
doaj   +1 more source

Living on the Edge of the CNS: Meninges Cell Diversity in Health and Disease

open access: yesFrontiers in Cellular Neuroscience, 2021
The meninges are the fibrous covering of the central nervous system (CNS) which contain vastly heterogeneous cell types within its three layers (dura, arachnoid, and pia).
Julia Derk   +8 more
doaj   +1 more source

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis [PDF]

open access: yes, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is ...
AA Poltera   +45 more
core   +7 more sources

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia   +20 more
wiley   +1 more source

Home - About - Disclaimer - Privacy