Results 11 to 20 of about 756,694 (263)
Genome wide association study identifies four loci for early onset schizophrenia
Early onset schizophrenia (EOS, defined as first onset of schizophrenia before age 18) is a rare form of schizophrenia (SCZ). Though genome-wide association studies (GWASs) have identified multiple risk variants for SCZ, most of the cases included in ...
Suqin Guo +8 more
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Background Over 200 schizophrenia risk loci have been identified by genome-wide association studies (GWASs). However, the majority of risk loci were identified in populations of European ancestry (EUR), potentially missing important biological insights ...
Jiewei Liu +11 more
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Bidirectional genetic overlap between bipolar disorder and intelligence
Background Bipolar disorder (BD) is a highly heritable psychiatric illness exhibiting substantial correlation with intelligence. Methods To investigate the shared genetic signatures between BD and intelligence, we utilized the summary statistics from ...
Meng-Yuan Shang +8 more
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Transcriptome-wide association study identifies new susceptibility genes and pathways for depression
Depression is the most prevalent mental disorder with substantial morbidity and mortality. Although genome-wide association studies (GWASs) have identified multiple risk variants for depression, due to the complicated gene regulatory mechanisms and ...
Xiaoyan Li +7 more
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Mental Models and Visualization
Mental models are internal representations of external phenomena. During their interaction with visualizations, the users construct mental models to represent these visualizations internally, to visually reason on them and solve problems with them. This chapter synthesizes existing theories on mental models and visualization to discuss their role and ...
Windhager, Florian, Mayr, Eva
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Modeling Mental Models: Their Use, Adaptation and Control
Using a proper mental model during mental processes is often crucial. Such a mental model has to be learnt and maintained; this involves mental model adaptation. Metacognition is applied to control use and adaptating in a context-sensitive manner. In this chapter, a second-order adaptive network model for handling mental models, covering their use ...
Canbaloğlu, Gülay, Treur, Jan
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The New Paradigm and Mental Models [PDF]
In a recent article in this journal, Johnson–Laird and colleagues argue that mental models theory (MMT) can integrate logical and probabilistic reasoning [1]. We argue that Johnson-Laird and colleagues make a radical revision of MMT, but to ill effect.\ud \ud This can best be seen in what they say about truth and validity (Box 1). Formerly ([2], p. 651)
Baratgin, Jean +5 more
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Mental models and metaphor [PDF]
This paper investigates the significa,lce of the mental models (MM) hypothesis for computational linguistics in general and for metaphor comprehension in particular. The N~4 hypothesis is the claim "that people understand the world by forming mental models.
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Perinatal Hypoxia and Ischemia in Animal Models of Schizophrenia
Intrauterine or perinatal complications constitute a major risk for psychiatric diseases. Infants who suffered from hypoxia–ischemia (HI) are at twofold risk to develop schizophrenia in later life.
Dimitri Hefter +5 more
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The Valley of Death is the gap between the completion of research and development (R&D) projects and their transition to innovation. A key aspect to explain it are mindsets, which are one of the most complex to explain due to the number of factors they ...
Jim Giraldo-Builes +3 more
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