Results 41 to 50 of about 11,662 (299)
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Reading the Mind through the Nose: Mentalizing Skills Predict Olfactory Performance
Brain Sciences, 2022 A growing body of literature suggests a close link between olfaction and social expertise. The current study examines whether mentalizing skills are related to olfactory discrimination performance.
Katrin T. Lübke +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Acta PsychologicaParental embodied mentalizing is about how parents show with their body that they hold in mind their infants' mind. The main study's aim was to explore what influences fathers' embodied mentalizing.
Hedvig Svendsrud +9 more
doaj +1 more source
MENTAL THERAPEUTICS IN NERVOUS AND MENTAL DISEASES [PDF]
American Journal of Psychiatry, 1901 I desire to present some thoughts on “Mental Therapeutics,” drawn mostly from experience, which may have a practical value in showing the importance of ideas and of mental states in their influence for good or evil upon disease. The subject is not new, but it is one which is worthy of more attention than it has received from the medical profession as a
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
European Journal of PsychotraumatologyBackground: Youth with care experience have often been affected by repeated victimization and exhibit high rates of post-traumatic stress symptoms (PTSS).
Olivia Lucia Marie Emmerich +3 more
doaj +1 more source
Inferences regarding oneself and others in the human brain
PLoS Biology, 2022 The human brain can infer one’s own and other individuals’ mental states through metacognition and mentalizing, respectively. A new study in PLOS Biology has implicated distinct brain regions of the medial prefrontal cortex (PFC) in metacognition and ...
Shinsuke Suzuki
doaj