Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang +6 more
wiley +1 more source
TRPM8 Regulates Mitochondrial Ca2+‐Dynamics, Temperature and Endoplasmic Reticulum‐Mitochondrial Contact Points in T Cell [PDF]
ABSTRACT TRPM8 is a cold temperature‐sensitive and non‐selective Ca2+‐channel. Previously we have observed that TRPM8 is endogenously expressed and affects T cell activation process. Now, we report that TRPM8 regulates functions of mitochondria and ER, two important sub‐cellular compartments.
Acharya T +5 more
europepmc +2 more sources
A Comparison of Two Formulas of Topical Menthol on Vascular Responses and Perceived Intensity Prior to and following a Bout of Maximum Voluntary Muscular Contractions (MVMCs) [PDF]
The purpose of this study was to compare the vascular responses in the brachial artery and perceived intensity of two different formulas of topical menthol gels prior to and following a bout of maximum voluntary muscular contractions (MVMCs).
Cybulski, Alyson +4 more
core +1 more source
Ring Formation in Sesquiterpene Synthesis: Biomimetic vs. Non‐Biomimetic Strategies
A short review of cyclase enzyme‐mediated ring formation in sesquiterpene biosynthesis is presented as a prelude to six case studies examining the merits and demerits of biomimetic vs. non‐biomimetic strategies for carbocyclisation in the total synthesis of this iconic natural product class.
Bohan Lin, Chen Dai, Alan C. Spivey
wiley +1 more source
Noninvasive Disease Diagnostics: The Swiss Contribution Highlights to Breath Analysis Research
Breath analysis networks across Switzerland linking health monitoring, clinical applications, population studies, and data‐driven public health decisions. ABSTRACT To celebrate the 125th anniversary of the Swiss Chemical Society, we present a review and perspective to highlight the recent research in breath analysis that has been conducted in ...
Stefan James Swift +6 more
wiley +1 more source
Enhancement of Exercise Capacity in the Heat With Repeated Menthol-Spray Application [PDF]
Purpose Exercise performance is impaired in the heat and a contributing factor to this decrement is thermal discomfort. Menthol-spraying of skin is one means of alleviating thermal discomfort but has yet to be shown to be ergogenic using single spray ...
Barwood, Martin +2 more
core +3 more sources
Abstract BACKGROUND Curcumin is a naturally derived polyphenol known for its potent biological properties. Its therapeutic potential, however, is hindered by low bioavailability. Nanostructured lipid carriers (NLCs) have emerged as advanced delivery systems to overcome such limitations. Natural deep eutectic solvents (NADESs) have garnered attention as
Kyriaki Safari +5 more
wiley +1 more source
A multiscale study of the penetration-enhancing mechanism of menthol
Objective: Transdermal drug delivery systems represent a critical focus in the pharmaceutics field; however, their use is limited by the fact that many drugs usually pass through the skin with low permeability.
Liping Chen +6 more
doaj +1 more source
Anterior Nasal Nerves: A Cadaveric Anatomic and Immunohistochemical Analysis
Anterior nasal nerves (ANNs) were identified in all cadavers, with more supplying the anterolateral nasal wall (ALNW) than the anterior portion of the inferior turbinate (IT), between the pyriform aperture (PA) and middle turbinate (MT). Both sensory and autonomic nerve markers were also identified in the ANNs.
John R. Craig +6 more
wiley +1 more source
Menthol cigarettes and the public health standard: a systematic review
Background Although menthol was not banned under the Tobacco Control Act, the law made it clear that this did not prevent the Food and Drug Administration from issuing a product standard to ban menthol to protect public health. The purpose of this review
Andrea C. Villanti +4 more
doaj +1 more source

