Results 21 to 30 of about 52,173 (255)

New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties

open access: yesPharmaceutics, 2023
This study describes the preparation, characterization, and influence of the enantiopure vs. racemic coformer on the physico-chemical properties of a pharmaceutical cocrystal.
Panpan Ma   +17 more
doaj   +1 more source

Improvement of the pharmacological activity of menthol via enzymatic β-anomer-selective glycosylation

open access: yesAMB Express, 2017
Menthol has a considerable cooling effect, but the use range of menthol is limited because of its extremely low solubility in water and inherent flavor.
Ha-Young Choi   +4 more
doaj   +1 more source

Menthol sensory qualities and smoking topography: a review of tobacco industry documents. [PDF]

open access: yes, 2011
ObjectiveTo determine what the tobacco industry knew about the potential effects of menthol on smoking topography-how a person smokes a cigarette.MethodsA snowball strategy was used to systematically search the Legacy Tobacco Documents Library (http ...
McCandless, Phyra M, Yerger, Valerie B
core   +2 more sources

Menthol cigarette smoking and obesity in young adult daily smokers in Hawaii

open access: yesPreventive Medicine Reports, 2015
This study investigates 1) the relationship between menthol cigarette smoking and obesity and 2) the association of body mass index with the nicotine metabolite ratio among menthol and non-menthol daily smokers aged 18–35 (n = 175).
Alyssa Marie M. Antonio   +18 more
doaj   +1 more source

A-type GABA receptor as a central target of TRPM8 agonist menthol. [PDF]

open access: yesPLoS ONE, 2008
Menthol is a widely-used cooling and flavoring agent derived from mint leaves. In the peripheral nervous system, menthol regulates sensory transduction by activating TRPM8 channels residing specifically in primary sensory neurons.
Xiao-Bing Zhang   +7 more
doaj   +1 more source

Topical Menthol, Ice, Peripheral Blood Flow, and Perceived Discomfort [PDF]

open access: yes, 2013
Context : Injury management commonly includes decreasing arterial blood flow to the affected site in an attempt to reduce microvascular blood flow and edema and limit the induction of inflammation.
Jacks, Dean E.   +2 more
core   +2 more sources

Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice. [PDF]

open access: yesPLoS ONE, 2015
Addition of menthol to cigarettes may be associated with increased initiation of smoking. The potential mechanisms underlying this association are not known.
Michael A Ha   +7 more
doaj   +1 more source

Engineered Saccharomyces cerevisiae for the De Novo Biosynthesis of (−)-Menthol

open access: yesJournal of Fungi, 2022
Menthol, a high-value commodity monoterpenoid chemical, holds an important market share commercially because of its distinct functions. The menthol on the market mainly originates from plant extraction, which is facing challenges such as the seasonal ...
Xueqin Lv   +7 more
doaj   +1 more source

In Vitro Consequences of Electronic-Cigarette Flavoring Exposure on the Immature Lung. [PDF]

open access: yes, 2019
Background: The developing lung is uniquely susceptible and may be at increased risk of injury with exposure to e-cigarette constituents. We hypothesize that cellular toxicity and airway and vascular responses with exposure to flavored refill solutions ...
Berkelhamer, Sara   +5 more
core   +2 more sources

Athlete perceptions of flavored, menthol-enhanced energy gels ingested prior to endurance exercise in the heat

open access: yesJournal of the International Society of Sports Nutrition, 2022
Background L-menthol evokes a cooling sensation by activating cold sensing cation channels. Menthol-enhanced fluids can be ergogenic during exercise in the heat by improving thermal perception; hence, the addition of menthol to energy gels may benefit ...
Roxanne M Vogel   +4 more
doaj   +1 more source

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