Results 51 to 60 of about 21,099 (235)

Electrical Stimulation of Trigeminal Nerve at the Anterior Nasal Septum in Healthy Individuals and Patients With Olfactory Dysfunction

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The intranasal trigeminal system contributes to the sense of smell. Its integrity in olfactory dysfunction (OD) may be crucial for future treatments. This study assessed trigeminal sensitivity in healthy individuals and patients with OD of different etiologies using electrical stimulation of the nasal mucosa.
Konstantinos Garefis, Susanne Weise, Pauline Hanslik, Coralie Mignot, Halina B. Stanley, Maxime Fieux, Camille Ferdenzi, Evangelia Tsakiropoulou, Clémentine Lipp, Arnaud Bertsch, Moustafa Bensafi, Iordanis Konstantinidis, Thomas Hummel   +12 more
wiley   +1 more source

Menthol-loaded PLGA Micro and Nanospheres: Synthesis, Characterization and Degradation in Artificial Saliva [PDF]

Materials Research, 2018
Menthol-loaded PLGA micro/nanospheres were synthesized using the multiple emulsion/solvent evaporation technique. Parameters such as stirring rate, external surfactant content, PLGA/menthol weight ratio, solvent evaporation and lyophilization time were ...
Juliana Pelisoli Holz, Marcia Karpinski Bottene, Vanusca Dalosto Jahno, Sandra Einloft, Rosane Ligabue   +4 more
doaj   +2 more sources

Kupfer(II)‐photokatalysierte Radikalannellierung von Nitroalkanen mit Alkenen oder Alkinen zur Synthese von Isoxazolinen und Isoxazolen

Angewandte Chemie, EarlyView.
Wir stellen ein Cu(II)‐photokatalytisches Verfahren vor, bei dem handelsübliche Nitroalkane für die Synthese von Isoxazolinen und Isoxazolen aus Alkenen bzw. Alkinen verwendet werden. Detaillierte mechanistische Untersuchungen ergaben, dass der breite Substratbereich, der sowohl aktivierte als auch nicht aktivierte Alkene und Alkine umfasst, auf einen ...
Sunaina Sardana, Aryaman Pattanaik, Julia Rehbein, Oliver Reiser   +3 more
wiley   +1 more source

Menthol cigarettes and smoking cessation behavior

Tobacco Induced Diseases, 2011
Although much is known about smoking cessation behavior, the vast majority of research has not assessed menthol as an independent factor. The objective of this review is to assess the effects, if any, that use of menthol cigarettes has on smoking ...
Allison C. Hoffman, Donna Miceli
doaj   +1 more source

Effects of Menthol on Nicotine Pharmacokinetic, Pharmacology and Dependence in Mice. [PDF]

PLoS ONE, 2015
Although menthol, a common flavoring additive to cigarettes, has been found to impact the addictive properties of nicotine cigarettes in smokers little is known about its pharmacological and molecular actions in the brain.
Shakir D Alsharari, Justin R King, Jacob C Nordman, Pretal P Muldoon, Asti Jackson, Andy Z X Zhu, Rachel F Tyndale, Nadine Kabbani, M Imad Damaj   +8 more
doaj   +1 more source

Effects on Smoking Behavior of Switching Menthol Smokers to Non-menthol Cigarettes

Nicotine & Tobacco Research, 2021
Abstract Introduction Bans of menthol characterizing flavor in cigarettes have been implemented in some localities and have been proposed more broadly. One proposed benefit of such a ban is to increase cessation rates among current menthol smokers.
Michael Kotlyar, Anne M Mills, Dorothy K. Hatsukami, Ryan Shanley, Sheena R Dufresne, Kolawole S. Okuyemi, Gretchen A Corcoran   +6 more
openaire   +3 more sources

Effect of Menthol on SFRP1 Expression Level and HIF-1α/VEGF Signaling in Diethylnitrosamine-induced Kidney Damage in Male Mice [PDF]

Journal of Ardabil University of Medical Sciences, 2023
Background: Many scientific Researches have shown that diethylnitrosamine, which is used to induce liver carcinoma, has destructive effects on the kidney. Menthol is a monoterpene type with antioxidant, anti-inflammatory, and anti-cancer effects.
Samaneh Alijanian, Masoumeh Asle Rousta, Golnaz Asaadi Tehrani   +2 more
doaj  

The distinctive role of menthol in pain and analgesia: Mechanisms, practices, and advances

Frontiers in Molecular Neuroscience, 2022
Menthol is an important flavoring additive that triggers a cooling sensation. Under physiological condition, low to moderate concentrations of menthol activate transient receptor potential cation channel subfamily M member 8 (TRPM8) in the primary ...
Ziping Li, Haoyue Zhang, Haoyue Zhang, Yigang Wang, Yigang Wang, Yize Li, Qing Li, Linlin Zhang   +7 more
doaj   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Menthol tobacco use is correlated with mental health symptoms in a national sample of young adults: implications for future health risks and policy recommendations

Tobacco Induced Diseases, 2016
Introduction Depression and anxiety are correlated with greater nicotine dependence, smoking persistence, and relapse back to smoking after a quit attempt.
Amy M. Cohn, Amanda L. Johnson, Elizabeth Hair, Jessica M. Rath, Andrea C. Villanti   +4 more
doaj   +1 more source