Results 21 to 30 of about 1,567 (140)

Methyl Salicylate-Loaded Nanogel: A Novel Approach for the Management of Rheumatoid Arthritis

Journal of Bio-X Research
Rheumatoid arthritis (RA) is a recurring and chronic autoimmune disorder that causes joint pain, stiffness, and inflammation because the immune system attacks the joints.
Rabia, Aafreen
doaj   +1 more source

Pushing Frontiers for Proteoglycans

Proteoglycan Research, Volume 4, Issue 2, April 2026.
ABSTRACT Almost half of proteins have one or more post‐translational glycosylation modifications involving the addition of glycan structures. Proteoglycans are a class of glycosylated proteins with one or more glycosaminoglycan (GAG) chains covalently attached to the core protein.
Marissa L. Maciej‐Hulme
wiley   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, Volume 21, Issue 2, March/April 2026.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Preclinical advances in antibodies against N‐terminal Aβ4‐x species for Alzheimer's disease and cerebral amyloid angiopathy

Ibrain, Volume 12, Issue 1, Page 52-64, Spring 2026.
This review provides an update on monoclonal and polyclonal antibodies developed to specifically target amyloid beta (Aβ) truncated species starting at residue phenylalanine 4 (Aβ4‐x) in Alzheimer's disease and cerebral amyloid angiopathy preclinical studies (in vitro and in vivo models).
Maria Luisa Valle, Donatello Arienzo
wiley   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

Animal Research and One Health, Volume 4, Issue 1, Page 14-27, February 2026.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang, Ao Guo, Lin Zhang, Shengru Wu, Juan Du, Taiyong Yu   +5 more
wiley   +1 more source

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, Volume 5, Issue 1, February 2026.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

Skeletogenic Expression of Integrin Alpha, Talin and Npnt Genes and Npnt Role in Sea Urchin Skeletogenesis

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 1, Page 7-19, January 2026.
Three integrin alpha genes and the cytoskeletal adaptor talin are enriched in sea urchin skeletogenic cells during early skeletogenesis. The extracellular matrix protein nephronectin (Npnt) is expressed in the skeletogenic cells throughout skeletogenesis and supports normal skeletal growth, highlighting a potential role for cell–matrix interactions in ...
Shanduo Chen, Tsvia Gildor, Prashant Tewari, Smadar Ben‐Tabou de‐Leon   +3 more
wiley   +1 more source

Amyloid Beta in Alzheimer's Disease: Mechanisms, Biomarker Potential, and Therapeutic Targets

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
The limited clinical efficacy of anti‐Aβ antibodies has challenged the Aβ hypothesis, compelling the integration of key mechanisms—including neuroinflammation, mitochondrial dysfunction, oxidative stress, and post‐translational modifications of Aβ—into a revised model of Alzheimer's disease.
Shamseddin Ahmadi, Shiler Khaledi, Kimia Ahmadi, Kambiz Hassanzadeh   +3 more
wiley   +1 more source

Tumor Development in Ulcerative Colitis: Perspectives From Biomechanical Characteristics

Development, Growth &Differentiation, Volume 67, Issue 9, Page 487-499, December 2025.
ABSTRACT Throughout our lifespan, sustaining orderly morphological structures for ensuring proper functioning of organs is imperative. Among these structures, the extracellular matrix (ECM) plays a pivotal role in sustaining organ and tissue homeostasis. Nevertheless, elucidating the role of abnormal ECM‐induced biomechanical microenvironmental changes
Hirotaka Tao
wiley   +1 more source

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, Volume 25, Issue 21-22, Page 102-150, November 2025.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source