Results 91 to 100 of about 267 (125)

Synthesis, molecular modelling, and biological evaluation of novel quinoxaline derivatives for treating type II diabetes. [PDF]

J Enzyme Inhib Med Chem
Alasmary FAS, Abdullah DA, Masand VH, Ben Bacha A, Omar Ebeid AM, El-Araby ME, Alafeefy AM.   +6 more
europepmc   +1 more source

Prevalence, resistance pattern, and molecular characterization of Staphylococcus aureus isolates from healthy animals and sick populations in Henan Province, China. [PDF]

Gut Pathog, 2018
Liu B, Sun H, Pan Y, Zhai Y, Cai T, Yuan X, Gao Y, He D, Liu J, Yuan L, Hu G.   +10 more
europepmc   +1 more source

Serotypes and antimicrobial susceptibility of Salmonella spp. isolated from farm animals in China. [PDF]

Front Microbiol, 2015
Kuang X, Hao H, Dai M, Wang Y, Ahmad I, Liu Z, Zonghui Y.   +6 more
europepmc   +1 more source

A Study of Resistome in Mexican Chili Powder as a Public Health Risk Factor. [PDF]

Antibiotics (Basel)
Mena Navarro MP, Espinosa Bernal MA, Alvarado Osuna C, Ramos López MÁ, Amaro Reyes A, Arvizu Gómez JL, Pacheco Aguilar JR, Saldaña Gutiérrez C, Pérez Moreno V, Rodríguez Morales JA, García Gutiérrez MC, Álvarez Hidalgo E, Nuñez Ramírez J, Hernández Flores JL, Campos Guillén J.   +14 more
europepmc   +1 more source

Identification of Eight in vivo Metabolites of Mequindox in Scophthalmus maximus by using UHPLC-MS/MS

Food Science and Human Wellness
Xin Mao, Yifang Hong, Xinru Li, Haoxian An, Shuang Zhou, Huihui Liu, Bin Qiu, Yanli You   +7 more
openaire   +1 more source

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Metabolism of mequindox in liver microsomes of rats, chicken and pigs

Rapid Communications in Mass Spectrometry, 2010
Abstract Mequindox, 3‐methyl‐2‐quinoxalinacetyl‐1,4‐dioxide, is a quinoxaline‐ N , N ‐dioxide used in veterinary medicine as a antibacterial in China.
Zhao-Ying, Liu, Ling-Li, Huang, Dong-Mei, Chen, Zong-Hui, Yuan   +3 more
openaire   +4 more sources

Genotoxicity evaluation of Mequindox in different short-term tests

Food and Chemical Toxicology, 2013
Quinoxaline-1,4-dioxides (QdNOs) are the potent heterocyclic N-oxides with interesting biological properties such as antibacterial, anticandida, antitubercular, anticancer and antiprotozoal activities. Here, we tested and compared the mequindox (MEQ) for mutagenic abilities in a battery of different short term tests according to OECD guidelines.
Awais, Ihsan, Xu, Wang, Hong-Gong, Tu, Wei, Zhang, Meng-Hong, Dai, De-Peng, Peng, Yu-Lian, Wang, Ling-Li, Huang, Dong-Mei, Chen, Shazia, Mannan, Yan-Fei, Tao, Zhen-Li, Liu, Zong-Hui, Yuan   +12 more
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Dynamic Metabolic Response of Mice to Acute Mequindox Exposure

Journal of Proteome Research, 2011
Mequindox is used as a veterinary antibiotic drug. As part of systematic investigations into mequindox as a veterinary medicine and its subsequent applications in food safety, we conducted the investigation to assess the metabolic response of mice to mequindox using metabonomics, which combines NMR metabolic profiles of biofluids or tissues and pattern
Xiu-Ju, Zhao, Chongyang, Huang, Hehua, Lei, Xiu, Nie, Huiru, Tang, Yulan, Wang   +5 more
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Acute and subchronic toxicological evaluation of Mequindox in Wistar rats

Regulatory Toxicology and Pharmacology, 2010
We studied an acute and subchronic oral toxicity of Mequindox (MEQ), a quinoxaline 1,4-dioxide antimicrobial promoter, in Wistar rats according to OECD guidelines. For acute toxicity study, single doses of MEQ at 175, 550 and 2000 mg/kg b.w. were administered to rats by oral gavage. The calculated LD(50) was 550 mg/kg b.w.
Awais, Ihsan, Xu, Wang, Xian-ju, Huang, Yu, Liu, Qin, Liu, Wen, Zhou, Zong-hui, Yuan   +6 more
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Casein nanoparticles as oral delivery carriers of mequindox for the improved bioavailability

Colloids and Surfaces B: Biointerfaces, 2020
Mequindox (Meq) is a promising broad-spectrum antibacterial agent, but the clinical application of Meq has been hampered by its low oral bioavailability. Casein (Cas) can bind to a variety of poorly water-soluble drugs to improve their water solubility through a micellar solubilization mechanism. Here, a low-cost and convenient method was introduced to
Li, Chen, Junxia, Wei, Mengying, An, Li, Zhang, Shiyu, Lin, Gang, Shu, Zhixiang, Yuan, Juchun, Lin, Guangneng, Peng, Xiaoxia, Liang, Lizi, Yin, Wei, Zhang, Ling, Zhao, Hualin, Fu   +13 more
openaire   +2 more sources