Results 91 to 100 of about 403 (128)

Synthesis, molecular modelling, and biological evaluation of novel quinoxaline derivatives for treating type II diabetes. [PDF]

open access: yesJ Enzyme Inhib Med Chem
Alasmary FAS   +6 more
europepmc   +1 more source

A Study of Resistome in Mexican Chili Powder as a Public Health Risk Factor. [PDF]

open access: yesAntibiotics (Basel)
Mena Navarro MP   +14 more
europepmc   +1 more source

Casein nanoparticles as oral delivery carriers of mequindox for the improved bioavailability.

Colloids and Surfaces B: Biointerfaces, 2020
Mequindox (Meq) is a promising broad-spectrum antibacterial agent, but the clinical application of Meq has been hampered by its low oral bioavailability.
L. Chen   +13 more
semanticscholar   +3 more sources

Mequindox induces apoptosis, DNA damage, and carcinogenicity in Wistar rats.

Food and Chemical Toxicology, 2019
Mequindox (MEQ) is a synthetic antibacterial agent. Recent studies showed that MEQ and its primary metabolites exhibit strong genotoxicity to mammalian cells, and MEQ induced carcinogenicity in mice.
Qianying Liu   +12 more
semanticscholar   +3 more sources

Solubility and dissolution thermodynamic properties of Mequindox in binary solvent mixtures

Journal of Molecular Liquids, 2020
The solubility of Mequindox(MEQ) in two kinds of binary mixtures(acetone+isopropanol; N-propanol+N-butanol) with different ratio was determined by shake flask method through UV–Vis spectrophotometer over the temperature from 293.15 to 323.15 K at ...
Shiqi Chen   +14 more
semanticscholar   +2 more sources

Genotoxicity evaluation of Mequindox in different short-term tests.

Food and Chemical Toxicology, 2013
Quinoxaline-1,4-dioxides (QdNOs) are the potent heterocyclic N-oxides with interesting biological properties such as antibacterial, anticandida, antitubercular, anticancer and antiprotozoal activities. Here, we tested and compared the mequindox (MEQ) for mutagenic abilities in a battery of different short term tests according to OECD guidelines.
Awais Ihsan   +12 more
semanticscholar   +3 more sources

Physiologically based pharmacokinetic model for quinocetone in pigs and extrapolation to mequindox

open access: yesFood Additives & Contaminants: Part A, 2016
Physiologically based pharmacokinetic (PBPK) models are scientific methods used to predict veterinary drug residues that may occur in food-producing animals, and which have powerful extrapolation ability. Quinocetone (QCT) and mequindox (MEQ) are widely used in China for the prevention of bacterial infections and promoting animal growth, but their ...
Xudong Zhu   +7 more
semanticscholar   +3 more sources

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