Physiologically based pharmacokinetic model for quinocetone in pigs and extrapolation to mequindox
Food Additives & Contaminants: Part A, 2016 Physiologically based pharmacokinetic (PBPK) models are scientific methods used to predict veterinary drug residues that may occur in food-producing animals, and which have powerful extrapolation ability. Quinocetone (QCT) and mequindox (MEQ) are widely used in China for the prevention of bacterial infections and promoting animal growth, but their ...
Xudong, Zhu +7 more
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Metabolic Profiling Analysis of the Alleviation Effect of the Fractions of Niuhuang Jiedu Tablet on Realgar [PDF]
, 2018 Niuhuang Jiedu Tablet (NJT) is a classical formula in treating acute tonsillitis, pharyngitis, and so on. In the formula, significant level of Realgar as a potentially toxic element is contained.
Haifeng Wang +4 more
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EVALUATION OF THE ACUTE AND SUBCHRONIC TOXICITY OF Aster tataricus L. F. [PDF]
, 2016 Backgr ound: Aster tataricus L. f. is used as a traditional Chinese drug to relieve cough and asthma symptoms and to eliminate phlegm. However, Aster tataricus L. f.
Ge, Liang +7 more
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Proteomics and metabolomics characterizing the pathophysiology of adaptive reactions to the metabolic challenges during the transition from late pregnancy to early lactation in dairy cows [PDF]
, 2017 The transition from late pregnancy to early lactation is a critical period in a dairy cow's life due to the rapidly increasing drain of nutrients from the maternal organism towards the foetus and into colostrum and milk.
C. Lecchi +3 more
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A Critical Review of Bioaccumulation and Biotransformation of Organic Chemicals in Birds [PDF]
, 2022 A literature review of bioaccumulation and biotransformation of organic chemicals in birds was undertaken, aiming to support scoping and prioritization of future research.
Deglin, Sandrine +9 more
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Study of acute and subacute toxicities and genotoxic and mutagenic potentials of the lyophilized extract of Campomanesia sessiliflora (O.Berg) mattos leaves in wistar rats [PDF]
Campomanesia sessiliflora (O.Berg) Mattos is a Brazilian native plant species used in a popular medicinal tea for treating gastrointestinal, urinary, and dermatological pathologies.
Araújo, Flávio Henrique Souza de +9 more
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Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust particulate (DEP) exposure [PDF]
Background Particulate matter 2.5 (PM2.5) deposition in the lung’s alveolar capillary region (ACR) is significantly associated with respiratory disease development, yet the molecular mechanisms are not completely understood.
Martin, Elizabeth M. +3 more
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Precision Nutrition and Metabolic Syndrome Management [PDF]
, 2018 Precision nutrition is an emerging concept encompassing an integrated action considering not only the genetic/epigenetic makeup and ethnic aspects of individuals, but other personalized phenotypical features, such as family and individual clinical issues,
Alfredo J. Martínez (Ed.) +1 more
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What's in a chicken: using NMR metabolomics to investigate stress in broiler chickens [PDF]
, 2021 Stress has the potential to adversely affect the health of chickens. Using Nuclear Magnetic Resonance (NMR) spectroscopy-based metabolomics objectives were to: ascertain the effects of physiological stress on the metabolomes of chicken liver, kidney, and
Brown, Catherine
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Background:Over the last ten years, three-dimensional organoid culture has garnered renewed interest, as organoids generated from primary cells or stem cells with cell associations and functions similar to organs in vivo can be a powerful tool to study ...
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