Results 101 to 110 of about 18,495 (202)
Will the Dermatoscopic Characterization of Merkel Cell Carcinoma Remain an Enigma?
International Journal of Dermatology, EarlyView.
Cliff Rosendahl, Alan Cameron
wiley +1 more source
Cancer Medicine, Volume 15, Issue 3, March 2026.ABSTRACT Background Carbohydrate antigen 19–9 (CA19‐9) is a cell surface glycoprotein widely used as a diagnostic and prognostic serum marker for monitoring pancreatic cancer. The aim of this study was to evaluate the prevalence and clinical relevance of CA19‐9 expression in human cancer. Methods To comprehensively determine the prevalence and clinical
Nina Schraps +31 more
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IJU Case Reports, Volume 9, Issue 2, March 2026.ABSTRACT Introduction Cytokine release syndrome (CRS) is a rare immune‐related adverse event of immune checkpoint inhibitors (ICIs). At present, its association with avelumab–axitinib therapy for renal cell carcinoma (RCC) has yet to be reported. Differentiating early CRS from an infusion‐related reaction (IRR) is clinically challenging, particularly ...
Rio Shibata +7 more
wiley +1 more source
The Journal of Pathology, Volume 268, Issue 3, Page 249-262, March 2026.Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou +3 more
wiley +1 more source
Drug Product Development of Lipid Nanoparticle‐Based mRNA Therapeutics and Vaccines
WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.Overview of the development path from an mRNA–lipid nanoparticle (LNP) concept to a licensed drug product, covering LNP design, manufacturing process development, formulation, and analytical characterization. ABSTRACT Lipid nanoparticles (LNP) are currently the most relevant non‐viral delivery systems for mRNA and occasionally for smaller nucleic acids
Gideon Kersten +4 more
wiley +1 more source
Andrology, Volume 14, Issue 3, Page 661-701, March 2026.Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani +6 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 6, Page 778-794, March 2026.Statin therapy in cirrhosis may confer a survival benefit while reducing the risk of hepatic decompensation and hepatocellular carcinoma. ABSTRACT Background The role of statins in cirrhosis remains controversial. Historically restricted due to safety concerns, emerging evidence highlights potential pleiotropic benefits, though effects on mortality and
Bernardo de Faria Moraes +8 more
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British Journal of Pharmacology, Volume 183, Issue 6, Page 1250-1270, March 2026.Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
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Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
British Journal of Pharmacology, Volume 183, Issue 6, Page 1271-1287, March 2026.Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
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JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 3, Page 319-325, March 2026.Summary Background In cutaneous squamous cell carcinoma (cSCC), there is a paucity of data regarding local recurrence (LR) and regional lymph node metastasis (LM) as precursors to tumor death. Patients and Methods We estimated parameters of a multistate model with a proportion of patients without risk of progression using maximum likelihood.
Helmut Breuninger +3 more
wiley +1 more source