Results 121 to 130 of about 4,040 (201)

Mutant prevention concentrations, in vitro resistance evolution dynamics, and mechanisms of resistance to imipenem and imipenem/relebactam in carbapenem-susceptible Klebsiella pneumoniae isolates showing ceftazidime/avibactam resistance [PDF]

[Abstract] Klebsiella pneumoniae carbapenemase (KPC) variants selected during ceftazidime/avibactam treatment usually develop susceptibility to carbapenems and carbapenem/β-lactamase inhibitors, such as imipenem and imipenem/relebactam.
Aja-Macaya, Pablo, Alonso-García, Isaac, Arca-Suárez, Jorge, Beceiro, Alejandro, Blanco-Martín, Tania, Bou, Germán, Fernández-López, María del Carmen, Gato, Eva, González-Pinto, Lucía, Martínez-Martínez, Luis, Outeda-García, Michelle, Pedraza-Merino, Rosa, Rodríguez-Coello, Arianna, Rodríguez-Pallares, Salud, Sánchez-Peña, Lucía, Vázquez-Ucha, Juan Carlos   +15 more
core   +1 more source

Characterization of Enterobacter cloacae and Citrobacter freundii Species Complex Isolates with Decreased Susceptibility to Cephalosporins from United States Hospitals and Activity of Aztreonam–Avibactam and Comparator Agents (2019–2023)

Antibiotics
Background: Citrobacter freundii (CFC) and Enterobacter cloacae (ECLC) species complexes represent important causes of hospital-associated infections, frequently are related to outbreaks, and have a great ability to develop antimicrobial resistance.
Helio S. Sader, Timothy B. Doyle, John H. Kimbrough, Rodrigo E. Mendes, Mariana Castanheira   +4 more
doaj   +1 more source

Antimicrobial Activity of Aztreonam-Avibactam and Other β-Lactamase Inhibitor Combinations Tested Against Enterobacterales Isolates from Pediatric Patients from United States Medical Centers (2019–2023)

Antibiotics
Objective: To evaluate the antimicrobial susceptibility of Enterobacterales isolated from pediatric patients. Methods: A total of 5723 isolates were consecutively collected (1/patient) from pediatric patients (
Helio S. Sader, Marisa L. Winkler, Krisztina M. Papp-Wallace, Rodrigo E. Mendes, Mariana Castanheira   +4 more
doaj   +1 more source

Increased blaKPC Copy Number and OmpK35 and OmpK36 Porins Disruption Mediated Resistance to Imipenem/ Relebactam and Meropenem/Vaborbactam in a KPC-Producing Klebsiella pneumoniae Clinical Isolate [PDF]

, 2022
Bianco, Gabriele, Boattini, Matteo, Costa, Cristina   +2 more
core   +1 more source

Complete genome sequences of KPC-producing <i>Klebsiella pneumoniae</i> isolates pre- and post-development of meropenem/vaborbactam resistance. [PDF]

Microbiol Resour Announc
Ozer EA, Nozick SH, Singh N, Watkins JV, Hauser AR, Bulman ZP.   +5 more
europepmc   +1 more source

Aminoglycosides enhance meropenem/vaborbactam activity against KPC-producing <i>Klebsiella pneumoniae</i> in the hollow fiber infection model. [PDF]

Antimicrob Agents Chemother
Singh N, Jogan CML, Zang Y, Shan X, Lang Y, Karunanidhi A, Watkins JV, Curry BN, Tamma PD, Nozick SH, Ozer EA, Hauser AR, Bulitta JB, Bulman ZP.   +13 more
europepmc   +1 more source

Unlocking potentials: the impact of meropenem, meropenem-vaborbactam, and ceftazidime-avibactam in combating carbapenem-resistant Enterobacter cloacae. [PDF]

Antimicrob Agents Chemother
Lavoie T, Sierra T, Daffinee K, Pogue JM, Achour B, LaPlante K.   +5 more
europepmc   +1 more source

Targeting carbapenem-resistant and hypervirulent Klebsiella pneumoniae: in vitro evaluation of cefepime/zidebactam, aztreonam/avibactam, imipenem/relebactam, and meropenem/vaborbactam. [PDF]

BMC Infect Dis
Li Y, Li Y, Jia X, Mao H, Li D, Zhang J.
europepmc   +1 more source

Outline of Meropenem-Vaborbactam for the Treatment of Carbapenem-Resistant Enterobacteriaceae

International Journal of Pharmaceutical Sciences Review and Research, 2023
Dr. Kush Nimron, Dr. Johncy Nathasha
openaire   +1 more source

In vivo pharmacokinetic analysis of meropenem/vaborbactam during continuous venovenous haemodialysis

Journal of Antimicrobial Chemotherapy, 2019
Wesley D Kufel, Ambika P Eranki, Kristopher M Paolino, Andrea Call, Christopher D Miller, Bryan T Mogle   +5 more
openaire   +2 more sources