Results 1 to 10 of about 85,740 (261)

A Comparative Study of Clinical Presentation and Risk Factors for Adverse Outcome in Patients Hospitalised with Acute Respiratory Disease Due to MERS Coronavirus or Other Causes. [PDF]

PLoS ONE, 2016
Middle East Respiratory syndrome (MERS) first emerged in Saudi Arabia in 2012 and remains a global health concern. The objective of this study was to compare the clinical features and risk factors for adverse outcome in patients with RT-PCR confirmed ...
Musa A Garbati, Shamsudeen F Fagbo, Vicky J Fang, Leila Skakni, Mercy Joseph, Tariq A Wani, Benjamin J Cowling, Malik Peiris, Ahmed Hakawi   +8 more
doaj   +4 more sources

On-site detection of MERS-CoV infections in a camel slaughterhouse in Kenya using a commercial rapid antigen test [PDF]

Frontiers in Veterinary Science
BackgroundMiddle East respiratory syndrome coronavirus (MERS-CoV) poses a significant public health risk, with dromedary camels being the primary reservoir hosts.
Brian Maina Ogoti, Brian Maina Ogoti, Brian Maina Ogoti, Victor Riitho, Victor Riitho, Victor Riitho, Jordi Rodon, Nyamai Mutono, Nyamai Mutono, Nyamai Mutono, Julia Tesch, Julius Oyugi, Marianne W. Mureithi, Marianne W. Mureithi, Victor M. Corman, Victor M. Corman, Victor M. Corman, Christian Drosten, Christian Drosten, Christian Drosten, Johanna Wildemann, Samuel M. Thumbi, Samuel M. Thumbi, Samuel M. Thumbi, Samuel M. Thumbi, Marcel A. Müller, Marcel A. Müller   +26 more
doaj   +2 more sources

Colostrum from MERS-CoV seropositive camels for MERS prophylaxis and SARS-CoV-2 infection, a placebo controlled randomized trial [PDF]

Scientific Reports
COVID-19 pandemic is currently relatively controlled, mainly due to effective vaccines. Preparedness for future outbreaks should include means for reducing transmission of SARS-CoV-2 and other coronaviruses like MERS-CoV.
Hagit Masika, Meir Cherniak, Yelena Britan-Rosich, Yonatan Oster, Daniel Grupel, Ahmad Nama, Batel Nissan, David Planer, Jacob Strahilevitz, Eitan Israeli, Sujata Kumari, Orna Mor, Saveliy Kirillov, Joel Alter, Moshe Dessau, Jamal Fahoum, Einav Cohen-Kfir, Matan Golan, Reuven Wiener, Dan David, Reaan Amer, Alexander Rouvinski, Hila Elinav   +22 more
doaj   +2 more sources

Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus [PDF]

mBio, 2014
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first documented in the Kingdom of Saudi Arabia (KSA) in 2012 and, to date, has been identified in 180 cases with 43% mortality.
Matthew Cotten, Simon J. Watson, Alimuddin I. Zumla, Hatem Q. Makhdoom, Anne L. Palser, Swee Hoe Ong, Abdullah A. Al Rabeeah, Rafat F. Alhakeem, Abdullah Assiri, Jaffar A. Al-Tawfiq, Ali Albarrak, Mazin Barry, Atef Shibl, Fahad A. Alrabiah, Sami Hajjar, Hanan H. Balkhy, Hesham Flemban, Andrew Rambaut, Paul Kellam, Ziad A. Memish   +19 more
doaj   +5 more sources

Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV. [PDF]

Cell Rep
Chao CW, Sprouse KR, Miranda MC, Catanzaro NJ, Hubbard ML, Addetia A, Stewart C, Brown JT, Dosey A, Valdez A, Ravichandran R, Hendricks GG, Ahlrichs M, Dobbins C, Hand A, McGowan J, Simmons B, Treichel C, Willoughby I, Walls AC, McGuire AT, Leaf EM, Baric RS, Schäfer A, Veesler D, King NP.   +25 more
europepmc   +3 more sources

Glycosylated Receptor-Binding-Domain-Targeting Mucosal Vaccines Protect Against SARS-CoV-2 Omicron and MERS-CoV [PDF]

Vaccines
Background. The pathogenic coronaviruses (CoVs) MERS-CoV and SARS-CoV-2, which are responsible for the MERS outbreak and the COVID-19 pandemic, respectively, continue to infect humans, with significant adverse outcomes.
Xiaoqing Guan, Abhishek K. Verma, Qian Liu, Melissa Palacios, Abby E. Odle, Stanley Perlman, Lanying Du   +6 more
doaj   +2 more sources

Impact of MERS-CoV and SARS-CoV-2 Viral Infection on Immunoglobulin-IgG Cross-Reactivity

Vaccines, 2023
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a considerable threat to public health and global economies. SARS-CoV-2 has largely affected a vast world population and was declared a COVID-19 pandemic outbreak, with a substantial ...
Joud Mohammed AlKhalifah, Waleed Seddiq, Mohammed Abdullah Alshehri, Abdulkarim Alhetheel, Ahmed Albarrag, Sultan Ayoub Meo, Jaffar A. Al-Tawfiq, Mazin Barry   +7 more
doaj   +1 more source

Evaluation of a Rapid Immunochromatographic Middle East Respiratory Syndrome Coronavirus Antigen Detection Assay

Infectious Microbes & Diseases, 2022
. Middle East respiratory syndrome coronavirus (MERS-CoV) infection in humans has a high mortality of >30%. Dromedaries are the reservoir of MERS-CoV and the main source of human infections.
Susanna Kar-Pui Lau, Kenneth Sze-Ming Li, Jade Lee-Lee Teng, Sunitha Joseph, Hayes Kam-Hei Luk, Joshua Fung, Ulrich Wernery, Patrick Chiu-Yat Woo   +7 more
doaj   +1 more source

Enhancing immune protection against MERS-CoV: the synergistic effect of proteolytic cleavage sites and the fusion peptide and RBD domain targeting VLP immunization

Frontiers in Immunology, 2023
IntroductionThe Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic infectious virus that has caused significant outbreaks in the Middle East and beyond.
Jeein Oh, Uni Park, Juhyung Kim, Kyeongseok Jeon, Kyeongseok Jeon, Chulwoo Kim, Nam-Hyuk Cho, Nam-Hyuk Cho, Nam-Hyuk Cho, Youn Soo Choi, Youn Soo Choi, Youn Soo Choi   +11 more
doaj   +1 more source

Liposome-Mediated Delivery of MERS Antigen Induces Potent Humoral and Cell-Mediated Immune Response in Mice

Molecules, 2022
The advancements in the field of nanotechnology have provided a great platform for the development of effective antiviral vaccines. Liposome-mediated delivery of antigens has been shown to induce the antigen-specific stimulation of the humoral and cell ...
Masood Alam Khan, Ajamaluddin Malik, Mohammad A. Alzohairy, Abdulmohsen M. Alruwetei, Bader Y. Alhatlani, Osamah Al Rugaie, Arif Khan   +6 more
doaj   +1 more source