Results 11 to 20 of about 81,795 (214)

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines. [PDF]

PLoS ONE, 2013
An emerging respiratory infectious disease with high mortality, Middle East respiratory syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was first reported in 2012 in Saudi Arabia and has now spread to eight countries.
Lanying Du, Zhihua Kou, Cuiqing Ma, Xinrong Tao, Lili Wang, Guangyu Zhao, Yaoqing Chen, Fei Yu, Chien-Te K Tseng, Yusen Zhou, Shibo Jiang   +10 more
doaj   +1 more source

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

Emerging Microbes and Infections, 2020
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) causes a severe respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry into target cells.
Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Alexander Prokscha, Hassan Y. Naim, Marcel A. Müller, Christian Drosten, Stefan Pöhlmann, Markus Hoffmann   +8 more
doaj   +1 more source

Comparing the Immunogenicity and Protective Effects of Three MERS-CoV Inactivation Methods in Mice

Vaccines, 2022
The Middle East respiratory syndrome (MERS) is a fatal acute viral respiratory disease caused by MERS-coronavirus (MERS-CoV) infection. To date, no vaccine has been approved for MERS-CoV despite continuing outbreaks.
Nayoung Kim, Tae-Young Lee, Hansaem Lee, Jeong-Sun Yang, Kyung-Chang Kim, Joo-Yeon Lee, Hyun-Joo Kim   +6 more
doaj   +1 more source

MERS-CoV in Arabian camels in Africa and Central Asia [PDF]

, 2017
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causing infections in humans is genetically indistinguishable from the virus found in Arabian camels (dromedaries) in the Middle East. Although no primary human case of MERS was reported outside the
Chan, Samuel M.S., Chevalier, Véronique, Chu, Daniel K.W., Miguel, Eve, Peiris, Malik, Perera, Ranawaka A.P.M., Poon, Leo L.M., Roger, François   +7 more
core   +1 more source

Drivers of MERS-CoV transmission: what do we know? [PDF]

, 2016
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

Bactrian camels shed large quantities of Middle East respiratory syndrome coronavirus (MERS-CoV) after experimental infection

Emerging Microbes and Infections, 2019
In 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) emerged. To date, more than 2300 cases have been reported, with an approximate case fatality rate of 35%.
Danielle R. Adney, Michael Letko, Izabela K. Ragan, Dana Scott, Neeltje van Doremalen, Richard A. Bowen, Vincent J. Munster   +6 more
doaj   +1 more source

Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection

mBio, 2020
Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respiratory disease in humans and remains endemic in the Middle East since first being identified in 2012.
Kun Li, Zhuo Li, Christine Wohlford-Lenane, David K. Meyerholz, Rudragouda Channappanavar, Dong An, Stanley Perlman, Paul B. McCray, Biao He   +8 more
doaj   +1 more source

The medical and biochemical knowledge of health care professionals regarding the management of MERS-CoV: lessons from 2019 pilgrimage season in Al-Madinah, Saudi Arabia: A cross-sectional study

SVU - International Journal of Medical Sciences, 2023
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) epidemic was a serious healthcare concern not responding to conventional anti-viral therapies between 2012 and 2017 with high fatality rates.
Mariam Eid Alanzi, Mona Ali H. Albalawi , Saeed Kabrah, Yasmeen Talal Aljehani , Ahmed M. Okashah, Ayman M Yenbaawi, Sami Saleem Alrehaily , Areej Meshal Aljumaidi , Bandar Alkabli , Mohamed Hamed Almutairi , Riyadh Alghamdi, Manal Ali Alsharif , Zohoor Dahie Aljohani, Rehab Ismail H. Alribyawi , Sultan Ahmed H. Alluqmany , Ahlam Awad Aljohani , Suzan Talal Aljehani , Zain Jaber Alghamdi, Ahmad Mohsen Aljermaawi , Amir Gadhyan Aldebeesi , May Mohamed Almutairi, Khalid Eid Alanzi , Nusaybah Eid Alanzi , Saud Idris Umar , Fahad Majed Almutari, Hamza Bakeet Altorgmi, Osama Abdel-Mageed, Abdel-Raheem Donkol , Mohamed Abdel-Haleem, Hussam H. Baghdadi, Salah Mohamed El Sayed*   +30 more
doaj   +1 more source

Knowledge and practices of primary health care physicians regarding updated guidelines of MERS-CoV infection in Abha city

Journal of Family Medicine and Primary Care, 2019
Background: Human coronaviruses (hCoV) usually cause mild to moderate upper respiratory tract illnesses. The novel coronavirus (nCoV), or Middle East respiratory syndrome coronavirus (MERS-CoV), is a particular strain different from any other known hCoV ...
Saad Al-Amri, Rishi Bharti, Safar A Alsaleem, Hassan M Al-Musa, Shweta Chaudhary, Ayub A Al-Shaikh   +5 more
doaj   +1 more source

Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns [PDF]

, 2016
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A., Omrani, Ali S.   +2 more
core   +1 more source