Results 51 to 60 of about 75,632 (172)

MERS-CoV at the animal–human interface: inputs on exposure pathways from an expert-opinion elicitation [PDF]

, 2016
Nearly 4 years after the first report of the emergence of Middle-East respiratory syndrome Coronavirus (MERS-CoV) and nearly 1800 human cases later, the ecology of MERS-CoV, its epidemiology, and more than risk factors of MERS-CoV transmission between ...
Anna Funk, Bernard Faye, Eve Miguel, Flavie Luce Goutard, FRANCOIS LOUIS ROGER, JS Malik Peiris, JS Malik Peiris, Maria D Van Kerkhove, Mathieu Bourgarel, Veronique Chevalier   +9 more
core   +2 more sources

Establishment of well-differentiated camelid airway cultures to study Middle East respiratory syndrome coronavirus. [PDF]

, 2022
In 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in Saudi Arabia and was mostly associated with severe respiratory illness in humans. Dromedary camels are the zoonotic reservoir for MERS-CoV. To investigate the biology of MERS-CoV
Chanfon Bätzner, Astrid, Dijkman, Ronald, Ebert, Nadine, Gad, Hans Henrik, Gantenbein, Hans, Gultom, Mitra, Gurtner, Corinne, Hartmann, Rune, Kratzel, Annika, Pfaender, Stephanie, Portmann, Jasmine, Posthaus, Horst, Stalder, Hanspeter, Thiel, Volker Earl, Zanolari, Patrik   +14 more
core   +1 more source

Infectious diseases epidemic threats and mass gatherings: refocusing global attention on the continuing spread of the Middle East Respiratory syndrome coronavirus (MERS-CoV) [PDF]

, 2016
Media and World Health Organization (WHO) attention on Zika virus transmission at the 2016 Rio Olympic Games and the 2015 Ebola virus outbreak in West Africa diverted the attention of global public health authorities from other lethal infectious diseases
Alagaili, AN, Azhar, EI, Cotten, M, Zumla, A   +3 more
core   +4 more sources

Near‐Infrared Fluorescent Single‐Walled Carbon Nanotubes for Biosensing

Small, EarlyView.
Near‐infrared fluorescent single‐walled carbon nanotubes (SWCNTs) stand out as versatile biosensors due to their spectral overlap with the biological transparency window, surface‐sensitive fluorescence emission, and chemical modularity. This review offers a concise guide to understanding the photophysics of SWCNTs, various functionalization strategies,
Srestha Basu, Gili Bisker
wiley   +1 more source

The sample of choice for detecting Middle East respiratory syndrome coronavirus in asymptomatic dromedary camels using real-time reverse-transcription polymerase chain reaction [PDF]

, 2016
The newly identified Middle East respiratory syndrome coronavirus (MERS-CoV), which causes severe respiratory disease, particularly in people with comorbidities, requires further investigation.
Al Dhahiry, S.H.S. (Said), Al Romaihi, H.E. (Hamad), Al-Marri, S.A. (Salih), Al-Mawlawi, N. (Naema), Al-Thani, M. (Mohamed), Alhajri, F. (Farhoud), AlHajri, M.M. (Mohd), El-Maghraby, M.M. (Mamdouh M.), El-Sayed, A.M. (Ahmed M.), Farag, E. (Elmoubasher), Ghobashy, H. (Hazem), Haagmans, B.L. (Bart), Koopmans D.V.M., M.P.G. (Marion), Lamers, M.M. (Mart M.), Mohran, K.A. (Khaled A.), Pas, S.D. (Suzan), Raj, V.S. (Stalin), Reusken, C.B.E.M. (Chantal), Smits, S.L. (Saskia), Voermans, J. (Jolanda)   +19 more
core   +1 more source

Dimeric DNA Aptamers for the Spike Protein of SARS‐CoV‐2 Derived from a Structured Library with Dual Random Domains

Small Methods, EarlyView.
Dimeric in a single go: A novel DNA aptamer library has been designed to yield dimeric aptamers in a single in vitro selection. Tested against the SARS‐CoV‐2 spike protein, this dual random domain (DRD) library with two 25‐nucleotide random regions and a 20‐nucleotide poly‐thymidine linker produced high‐affinity dimeric aptamers with KD values as low ...
Ryan Amini, Jian Ma, Zijie Zhang, Qing Wang, Jimmy Gu, Leyla Soleymani, Yingfu Li   +6 more
wiley   +1 more source

Evaluation of candidate vaccine approaches for MERS-CoV [PDF]

Nature Communications, 2015
AbstractThe emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) as a cause of severe respiratory disease highlights the need for effective approaches to CoV vaccine development. Efforts focused solely on the receptor-binding domain (RBD) of the viral Spike (S) glycoprotein may not optimize neutralizing antibody (NAb) responses. Here we
Wang, L, Shi, W, Joyce, MG, Modjarrad, K, Zhang, Y, Leung, K, Lees, CR, Zhou, T, Yassine, HM, Kanekiyo, M, Yang, Z-Y, Chen, X, Becker, MM, Freeman, M, Vogel, L, Johnson, JC, Olinger, G, Todd, JP, Bagci, U, Solomon, J, Mollura, DJ, Hensley, L, Jahrling, P, Denison, MR, Rao, SS, Subbarao, K, Kwong, PD, Mascola, JR, Kong, W-P, Graham, BS   +29 more
openaire   +4 more sources

Rapid and Sensitive Detection of RNA Viruses through Imaging of Marker Molecules Derived from Designed Circular DNA Probes

Small Methods, EarlyView.
This study presents a rapid and sensitive virus detection method that employs imaging of virus‐specific DNA markers. Utilizing specially designed single‐stranded circular DNA probes, this method captures RNA fragments from RNase‐digested viral genomes during the reverse transcriptase‐based reaction, resulting in double‐stranded markers that are ...
Yoon‐ha Jang, Taesoo Kim, Su‐jin Hong, Se‐yeon Kim, Hyeseung Hwang, Siwon Kim, Su‐a Kang, Nabin Won, Dogeun Kim, Min Jae Kim, Yong Pil Chong, Seongsoo Jang, Kyubong Jo, Kwang‐il Lim   +13 more
wiley   +1 more source

Development of Small-Molecule MERS-CoV Inhibitors [PDF]

Viruses, 2018
Middle East respiratory syndrome coronavirus (MERS-CoV) with potential to cause global pandemics remains a threat to the public health, security, and economy. In this review, we focus on advances in the research and development of small-molecule MERS-CoV inhibitors targeting different stages of the MERS-CoV life cycle, aiming to prevent or treat MERS ...
Fei Yu, Lanfang Hu, Naru Zhang, Yudan Su, Meng Su, Xiaoqian Deng, Chen He, Ruiying Liang, Lili Wang, Tianlei Ying, Shibo Jiang, Shibo Jiang   +11 more
openaire   +3 more sources

Estimating potential incidence of MERS-CoV associated with Hajj pilgrims to Saudi Arabia, 2014 [PDF]

, 2014
Between March and June 2014 the Kingdom of Saudi Arabia (KSA) had a large outbreak of MERS-CoV, renewing fears of a major outbreak during the Hajj this October.
Albarrak, Ali, Cummings, Derek A T, Ferguson, Neil M, Garske, Tini, Hakeem, Rafat, Lessler, Justin, Mills, Harriet, Rodriguez-Barraquer, Isabel, The MERS-CoV Scenario Modeling Working Group,, Truelove, Shaun, Van Kerkhove, Maria   +10 more
core   +1 more source