Results 81 to 90 of about 75,632 (172)

Bacterial Outer Membrane Vesicles: From Physics to Clinical

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou, Shuang Zou, Derong Dai, Liqing He, Xingyu Mou, Ninglin Zhao, Hong Li, Rui Bao   +7 more
wiley   +1 more source

Lack of detection of Middle East respiratory syndrome coronavirus in mild and severe respiratory infections in Catalonia, northeastern Spain [PDF]

, 2014
Surveillance of Middle East respiratory syndrome coronavirus (MERS-CoV) was conducted to explore the possible introduction and circulation of this novel virus in Catalonia, northeastern Spain.
Gonzalo, V., Isanta, R., Jané, M., Marcos, M.A., Martinez, A., Martínez, M.J., Mateu, A., Torner, N., Vila, J., Zboromyrska, Y.   +9 more
core   +3 more sources

IL‐37 Mitigates the Inflammatory Response in Macrophages Induced by SARS‐CoV‐2 Omicron Infection Through the NF‐κB Signaling Pathway

MedComm, Volume 6, Issue 6, June 2025.
IL‐37 mitigates the infiltration of macrophages and suppresses the production of macrophage‐associated chemokines (such as CCL3 and CCL4) induced by SARS‐CoV‐2 Omicron infection through NF‐κB signaling pathway. ABSTRACT The expression levels of macrophage‐associated cytokines are significantly greater in COVID‐19 patients than in healthy individuals ...
Feifei Qi, Yiwei Yan, Mingya Liu, Qi Lv, Yanfeng Xu, Ming Liu, Fengdi Li, Ran Deng, Xujian Liang, Shuyue Li, Guocui Mou, Linlin Bao   +11 more
wiley   +1 more source

Investigating COVID‐19‐Induced Adjustment Disorder Among Iranian Patients With Multiple Sclerosis in Pandemic Time

Neuropsychopharmacology Reports, Volume 45, Issue 2, June 2025.
The present study was to investigate COVID‐19‐induced ADs among Iranian patients living with multiple sclerosis (MS) in 2020. The present study established that AD in the patients with MS in pandemic time was at the moderate level. ABSTRACT Background The coronavirus disease 2019 (COVID‐19) outbreak raised many concerns along with physical and mental ...
Elahe Samami, Seyed Mohammad Baghbanian, Seyedeh Zeynab Hossein Nezhad, Zohreh Shahhosseini, Mahmood Moosazadeh, Forouzan Elyasi   +5 more
wiley   +1 more source

Middle East Respiratory Syndrome Coronavirus Transmission among Healthcare Workers: Implication for Infection Control [PDF]

, 2018
Background Many outbreaks of Middle East respiratory syndrome coronavirus (MERS-CoV) have occurred in health care settings and involved health care workers (HCWs).
Al-Tawfiq, Jaffar A., Alanazi, Marzouqa, Alfaraj, Sarah H., Altuwaijri, Talal A., Alzahrani, Nojoom, Memish, Ziad A.   +5 more
core   +1 more source

Functional implications of hexameric dynamics in SARS‐CoV‐2 Nsp15

Protein Science, Volume 34, Issue 6, June 2025.
Abstract SARS‐CoV‐2, the virus responsible for the COVID‐19 pandemic, has undergone continuous evolution, leading to the emergence of variants with altered transmissibility and immune evasion. For the non‐structural proteins (Nsps) of SARS‐CoV‐2, there are limited structural analyses of their naturally occurring mutations.
Manashi Sonowal, Gihan Ketawala, Nirupa Nagaratnam, Dhenugen Logeswaran, Shibom Basu, Daniele de Sanctis, Julien Orlans, Samuel L. Rose, Rebecca J. Jernigan, Hao Hu, Jose Domingo Meza Aguilar, Madurangi E. Ranaweera, Michele A. Zacks, Julian J.‐L. Chen, Debra T. Hansen, Lynn G. Schrag, Raimund Fromme, Sabine Botha, Petra Fromme   +18 more
wiley   +1 more source

A novel coronavirus, MERS-CoV

Uirusu, 2013
A novel human coronavirus was identified in Saudi Arabia and Qatar as the causative agent of severe acute respiratory diseases in 2012. The virus was termed Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and is taken notice of important coronavirus caused severe diseases to human after the outbreak of severe acute respiratory syndrome (SARS ...
openaire   +3 more sources

Deducing the Crystal Structure of MERS-CoV Helicase [PDF]

, 2019
RNA virus encodes a helicase essential for viral RNA transcription and replication when the genome size is larger than 7 kb. Coronavirus (CoV) has an exceptionally large RNA genome (~30 kb) and it encodes an essential replicase, the nonstructural protein 13 (nsp13), a member of superfamily 1 helicases.
Cui, Sheng, Hao, Wei
openaire   +3 more sources

Identification, validation, and characterization of approved and investigational drugs interfering with the SARS‐CoV‐2 endoribonuclease Nsp15

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou, Maria Kuzikov, Sara Afandi, Greta Kovacs, Sukrit Srivastava, Andrea Zaliani, Andrey Gruzinov, Guillaume Pompidor, Michele Lunelli, Golam Rizvee Ahmed, Jörg Labahn, Johanna Hakanpää, Björn Windshügel, Michael Kolbe   +13 more
wiley   +1 more source

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome [PDF]

, 2016
Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel virus that emerged in 2012, causing acute respiratory distress syndrome (ARDS), severe pneumonia-like symptoms, and multi-organ failure, with a case fatality rate of ~36%.
Baric, Ralph S., Beall, Anne, Cockrell, Adam S., Douglas, Madeline, Heise, Mark T., Jensen, Kara, Marasco, Wayne A., Scobey, Trevor, Tang, Xian-Chun, Yount, Boyd L.   +9 more
core   +2 more sources