Results 101 to 110 of about 373,900 (338)

Perspectives on Repurposed Drugs Based on Globally Accepted Therapeutic Guidelines to Combat SARS-CoV-2 Infection

Drug, Healthcare and Patient Safety, 2021
Rina Rosalia Department of Health Sciences, College of Science, Health, Engineering and Education (SHEE), Murdoch University – Dubai Campus, Dubai, United Arab EmiratesCorrespondence: Rina RosaliaDepartment of Health Sciences, College of Science ...
Rosalia R
doaj  

Interfacial Energy and Composition Controlled Self‐Stratification in Polyurethane Coatings

Macromolecular Materials and Engineering, EarlyView.
This study elucidates self‐stratification in polyurethane coatings driven by interfacial energies and composition‐dependent phase separation. Using XPS, SIMS, and Raman analyses, we reveal rapid formation of hydrophobic and hydrophilic layers and substrate‐dependent interfacial structures.
Gaurav Singhal, Lihong Lao, Michaeleen L. Pacholski, Harshad Shah, Junsi Gu, Bryan Caruso, Fabio Aguirre‐Vargas, Piyush Singh, Kshitish A. Patankar, Simon A. Rogers, Charles M. Schroeder, Paul V. Braun   +11 more
wiley   +1 more source

Newcastle disease virus-based MERS-CoV candidate vaccine elicits high-level and lasting neutralizing antibodies in Bactrian camels

Journal of Integrative Agriculture, 2017
: Middle East respiratory syndrome coronavirus (MERS-CoV), a member of the Coronaviridae family, is the causative pathogen for MERS that is characterized by high fever, pneumonia, acute respiratory distress syndrome (ARDS), as well as extrapulmonary ...
Ren-qiang LIU, Jin-ying GE, Jin-ling WANG, Yu SHAO, Hui-lei ZHANG, Jin-liang WANG, Zhi-yuan WEN, Zhi-gao BU   +7 more
doaj   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)

Health and Quality of Life Outcomes, 2019
Introduction Data are lacking on impact of Middle East Respiratory Syndrome (MERS) on health-related quality of life (HRQoL) among survivors. Methods We conducted a cross-sectional survey of MERS survivors who required hospitalization in Saudi Arabia ...
Sarah Batawi, Nehal Tarazan, Rajaa Al-Raddadi, Eman Al Qasim, Anees Sindi, Sameera AL Johni, Fahad M. Al-Hameed, Yaseen M. Arabi, Timothy M. Uyeki, Basem M. Alraddadi   +9 more
doaj   +1 more source

Mitigating Health Disparities Through Empathetic Policymaking During Times of Crisis

Public Administration and Development, EarlyView.
ABSTRACT The COVID‐19 pandemic greatly exacerbated the existing disparities and inequities in health and healthcare among historically marginalized populations. Today, these impacts still echo. These persistent structured inequities erode the public's trust in government, lead to failure in public policies, and result in worse health consequences ...
Yali Pang, Brittany Keegan, Robyn D. McDougle   +2 more
wiley   +1 more source

Identification of a Novel Inhibitor against Middle East Respiratory Syndrome Coronavirus

Viruses, 2017
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first isolated in 2012, and circulated worldwide with high mortality. The continual outbreaks of MERS-CoV highlight the importance of developing antiviral therapeutics.
Yaping Sun, Huaidong Zhang, Jian Shi, Zhe Zhang, Rui Gong   +4 more
doaj   +1 more source

The impact of COVID‐19 on public perceptions of wild meat in Central Africa

People and Nature, EarlyView.
Abstract Wild meat is a significant source of food and income generation in Central Africa. However, there is little knowledge of how the assumed link between COVID‐19 and wild meat consumption has been discussed by the media and received by the public. In this study, we conducted media content analysis of 264 articles published in 2019–2020 related to
Yuhan Li, Lude Kinzonzi, Paul Loundou, Divin Malekani, Krossy Mavakala, Christian Mikolo Yobo, Katharine Abernethy, Matilda Eve Dunn, Donald Midoko Iponga, Robert Mwinyihali, Joss Wright, Eleanor Jane Milner‐Gulland, Lauren Coad, Juliet H. Wright, Daniel W. S. Challender   +14 more
wiley   +1 more source

These are not the k-mers you are looking for: efficient online k-mer counting using a probabilistic data structure

, 2014
K-mer abundance analysis is widely used for many purposes in nucleotide sequence analysis, including data preprocessing for de novo assembly, repeat detection, and sequencing coverage estimation.
Brown, C. Titus, Canino-Koning, Rosangela, Howe, Adina Chuang, Pell, Jason, Zhang, Qingpeng   +4 more
core   +2 more sources

Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu, Elizabeth K. Harmon, Justin K. Craig, Huili Yao, Kevin P. Battaile, David K. Johnson, Sandhya Subramanian, Wesley C. Van Voorhis, Mario Rivera, Scott Lovell   +9 more
wiley   +1 more source