Results 101 to 110 of about 338,568 (266)

Identification of a Novel Inhibitor against Middle East Respiratory Syndrome Coronavirus

Viruses, 2017
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first isolated in 2012, and circulated worldwide with high mortality. The continual outbreaks of MERS-CoV highlight the importance of developing antiviral therapeutics.
Yaping Sun, Huaidong Zhang, Jian Shi, Zhe Zhang, Rui Gong   +4 more
doaj   +1 more source

These are not the k-mers you are looking for: efficient online k-mer counting using a probabilistic data structure

, 2014
K-mer abundance analysis is widely used for many purposes in nucleotide sequence analysis, including data preprocessing for de novo assembly, repeat detection, and sequencing coverage estimation.
Brown, C. Titus, Canino-Koning, Rosangela, Howe, Adina Chuang, Pell, Jason, Zhang, Qingpeng   +4 more
core   +2 more sources

A fractal pattern of hierarchical genetic population structure in mixed stocks across fish segregated by dams revealed by genomic resources for curimba Prochilodus lineatus

Journal of Fish Biology, EarlyView.
Abstract Genomic resources, new microsatellite markers and a novel observation of a fractal pattern in the genetic population structure are presented for curimba, Prochilodus lineatus, a freshwater migratory model species of South America. Our main goals were to investigate the presence of mixed fish stocks and the effects of damming‐induced ...
Gabriel M. Yazbeck, Gésica Aparecida Santana Nascimento, Leiliane Campos Carvalho, Raíssa Cristina Dias Graciano, Rosiane de Paula Santos, Rafael Sachetto Oliveira   +5 more
wiley   +1 more source

Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)

Health and Quality of Life Outcomes, 2019
Introduction Data are lacking on impact of Middle East Respiratory Syndrome (MERS) on health-related quality of life (HRQoL) among survivors. Methods We conducted a cross-sectional survey of MERS survivors who required hospitalization in Saudi Arabia ...
Sarah Batawi, Nehal Tarazan, Rajaa Al-Raddadi, Eman Al Qasim, Anees Sindi, Sameera AL Johni, Fahad M. Al-Hameed, Yaseen M. Arabi, Timothy M. Uyeki, Basem M. Alraddadi   +9 more
doaj   +1 more source

Multi‐omics analyses shed lights on the evolution and fruit development of Chinese raspberries (Rubus spp.)

Journal of Integrative Plant Biology, EarlyView.
High‐quality genomes of four wild raspberry species, analysis of their genetic relationships, identification of centromeres as markers for tracing their hybrid origins, exploration of fruit quality regulation, and discovery of a gene blocking anthocyanin transport and thus causing yellow fruits provides valuable resources for raspberry breeding ...
Ticao Zhang, Dengli Luo, Guodong Li, Huanchong Wang, Qiang Cao, Rengang Zhang, Yuran Li, Yingan Zhu, Chunhua Ma, Aaron Liston, Hang Sun, Qin Qiao   +11 more
wiley   +1 more source

Plastid genome structure and phylogenomics of the freshwater red algal order Batrachospermales (Rhodophyta)

Journal of Phycology, EarlyView.
Abstract For the freshwater red algal order Batrachospermales, the number of plastid genomes available is relatively small compared to the number of genera. Fully assembled plastid genomes can provide insights into plastid evolution and crucial data for phylogenetic reconstruction.
Roseanna M. Crowell, Nadia M. Lemes Da Silva, Monica O. Paiano, Morgan L. Vis, Orlando Necchi Jr.   +4 more
wiley   +1 more source

Sex Differences in Response to Viral Vector Vaccines-Implications for Future Vaccine Design. [PDF]

Immunol Rev
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Grewe I, Zoran T, Addo MM.
europepmc   +2 more sources

Mining statistically-solid k-mers for accurate NGS error correction

BMC Genomics, 2018
Background NGS data contains many machine-induced errors. The most advanced methods for the error correction heavily depend on the selection of solid k-mers. A solid k-mer is a k-mer frequently occurring in NGS reads.
Liang Zhao, Jin Xie, Lin Bai, Wen Chen, Mingju Wang, Zhonglei Zhang, Yiqi Wang, Zhe Zhao, Jinyan Li   +8 more
doaj   +1 more source

Whole genome sequencing of historical specimens from the world's largest fungal collection yields high‐quality assemblies

New Phytologist, EarlyView.
Summary High‐throughput molecular studies of museum specimens (museomics) have great potential in biodiversity research, but fungal historical collections have scarcely been examined, leading to no comprehensive methodological assessments. Here we present a whole genome sequencing (WGS) project conducted at the Fungarium of the Royal Botanic Gardens ...
Torda Varga, Roseina Woods, Frances Pitsillides, Rowena Hill, Alona Yu Biketova, Theo Llewellyn, Brandon J. P. Shaw, Emily Hodgson, Brigid Wong, Jasmine Le, Josepha Becker, Alexander J. Bradshaw, Seth L. E. Blake, Clementine Geeves, Quentin Levicky, Lottie Goodman, Ruben L. Mole, Sidney L. Reed, M. Carly Lin, Emily Read, Keenan Harris, Raquel Pino‐Bodas, László G. Nagy, Anna Bazzicalupo, Ester Gaya   +24 more
wiley   +1 more source

Cross-sectional study of MERS-CoV-specific RNA and antibodies in animals that have had contact with MERS patients in Saudi Arabia

Journal of Infection and Public Health, 2018
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly emerged coronavirus that is associated with a severe respiratory disease in humans in the Middle East. The epidemiological profiles of the MERS-CoV infections suggest zoonotic
Samy Kasem, Ibraheem Qasim, Ali Al-Hufofi, Osman Hashim, Ali Alkarar, Ali Abu-Obeida, Albagir Gaafer, Abdelhamid Elfadil, Ahmed Zaki, Ahmed Al-Romaihi, Nasereldeen Babekr, Nadr El-Harby, Raed Hussien, Ali AL-Sahaf, Ali Al-Doweriej, Faisal Bayoumi, Leo L.M. Poon, Daniel K.W. Chu, Malik Peiris, Ranawaka A.P.M. Perera   +19 more
doaj   +1 more source