Results 121 to 130 of about 467,339 (358)

Haplotype‐resolved genome and pan‐genome graphs reveal the impacts of structural variation on functional genome and feather colors in chickens

iMetaOmics, EarlyView.
This study built a Wenchang chicken haplotype genome and integrated it with 29 others to create a chicken pangenome atlas. Analysis of 354 chickens revealed 185,205 structural variations (SVs), with one‐third derived from homology‐based and transposable elements.
Lihong Gu, Chen Peng, Anhong Chen, Kaiyu Chen, Xinli Zheng, Dongyou Yu, Zhengguang Wang, Lingzhao Fang, George E. Liu, Pengju Zhao   +9 more
wiley   +1 more source

COVID-19 in the Shadows of MERS-CoV in the Kingdom of Saudi Arabia

Journal of Epidemiology and Global Health, 2020
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) has plagued the Middle East since it was first reported in 2012. Recently, at the end of December 2019, a cluster of pneumonia cases were reported from Wuhan city, Hubei Province, China, linked to a
M. Barry, M. Al Amri, Z. Memish
semanticscholar   +1 more source

De Novo Whole Genome Assemblies of Unusual Case‐Making Caddisflies (Trichoptera) Highlight Genomic Convergence in the Composition of the Major Silk Gene (h‐fibroin)

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
The major silk gene, h‐fibroin, was annotated in high‐quality genomes of two unusual case‐making Trichoptera. H‐Fibroin of Limnocentropus insolitus shows a similar amino acid composition to other case‐making species, while the amino acid composition of h‐fibroin of Phryganopsyche brunnea resembles that of retreat‐making species.
Xiling Deng, Steffen U. Pauls, Ryoichi B. Kuranishi, Paul B. Frandsen, Jacqueline Heckenhauer   +4 more
wiley   +1 more source

Determination of the Critical Exponents for the Isotropic-Nematic Phase Transition in a System of Long Rods on Two-dimensional Lattices: Universality of the Transition

, 2008
Monte Carlo simulations and finite-size scaling analysis have been carried out to study the critical behavior and universality for the isotropic-nematic phase transition in a system of long straight rigid rods of length $k$ ($k$-mers) on two-dimensional ...
A. J. Ramirez-Pastor, Binder K., D. A. Matoz-Fernandez, D. H. Linares, Fisher M. E., Flory P. J., Ghosh A., Kamieniarz G., Privman V., Selke W., Selke W., Tomé T., Vroege G. J.   +12 more
core   +1 more source

Mass spectrometry of dendrimers

Mass Spectrometry Reviews, EarlyView.
Abstract Mass spectrometry (MS) has become an essential technique to characterize dendrimers as it proved efficient at tackling analytical challenges raised by their peculiar onion‐like structure. Owing to their chemical diversity, this review covers benefits of MS methods as a function of dendrimer classes, discussing advantages and limitations of ...
McKenna J. Redding, Scott M. Grayson, Laurence Charles   +2 more
wiley   +1 more source

Potential Anti-Coronavirus Agents and the Pharmacologic Mechanisms

Drug Design, Development and Therapy, 2021
Yang Yang,1,* Xiao Cui,1,* Huaying Wei,1 Caiping Guo,1 Yulin Zhang2 1Department of Infectious Diseases, Beijing You an Hospital, Capital Medical University, Beijing Institute of Hepatology, Beijing, 100069, People’s Republic of China; 2Department ...
Yang Y, Cui X, Wei H, Guo C, Zhang Y
doaj  

Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection.

JCI Insight, 2019
Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 in the Kingdom of Saudi Arabia and has caused over 2400 cases and more than 800 deaths.
Kirsten A. Kulcsar, C. Coleman, S. Beck, M. Frieman   +3 more
semanticscholar   +1 more source

Degradation strategies for structural characterization of insoluble synthetic polymers by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract With the advent of soft ionization techniques such as electrospray (ESI) and matrix‐assisted laser desorption/ionization (MALDI) to produce intact gas‐phase ions from nonvolatile macromolecules, mass spectrometry has become an essential technique in the field of polymeric materials.
Thierry N. J. Fouquet, Robert B. Cody, Laurence Charles   +2 more
wiley   +1 more source

SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

Nature Communications, 2019
Autophagy is an essential cellular process affecting virus infections and other diseases and Beclin1 (BECN1) is one of its key regulators. Here, we identified S-phase kinase-associated protein 2 (SKP2) as E3 ligase that executes lysine-48-linked poly ...
N. Gassen, Daniela Niemeyer, D. Muth, V. Corman, S. Martinelli, Alwine Gassen, K. Hafner, Jan Papies, Kirstin Mösbauer, Andreas Zellner, A. Zannas, Alexander Herrmann, F. Holsboer, R. Brack-Werner, M. Boshart, B. Müller-Myhsok, C. Drosten, M. Müller, T. Rein   +18 more
semanticscholar   +1 more source

Emerging respiratory viral infections: MERS-CoV and influenza [PDF]

, 2014
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source