Results 61 to 70 of about 14,200 (285)

Drug repositioning of mesalamine via supramolecular nanoassembly for the treatment of drug-induced acute liver failure. [PDF]

Theranostics
Rationale: Acute liver failure (ALF) is characterized by rapid hepatic dysfunction, primarily caused by drug-induced hepatotoxicity. Due to the lack of satisfactory treatment options, ALF remains a fatal clinical disease, representing a grand challenge ...
Park B, Kim EH, Jang H, Kim Y, Ryu Y, Choi J, Shin D, Lee MC, Yang Y, Kim K, Lee S, Kim SH, Shim MK.   +12 more
europepmc   +2 more sources

Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease [PDF]

, 2017
Background/Aims: Identifying predictors of endoscopic recurrence (ER) has become very important to guide the decision of postoperative strategy. This study aimed to determine the rate of endoscopic recurrence until 12 months after ileocolic resection for
Carvalho, Pedro Boal, Cotter, José Almeida Berkeley, Gonçalves, Tiago Cúrdia, Monteiro, Sara, Moreira, Maria João   +4 more
core   +1 more source

Formulation and Evaluation of Enteric Coated Matrix Tablets of Mesalamine for Inflammatory Bowel Disease

Journal of Drug Delivery and Therapeutics, 2022
Mesalamine is a gold standard anti-inflammatory drug used to treat inflammatory bowel illnesses. It's usually used to treat and keep Ulcerative Colitis in remission in mild to moderate cases.
Nikita Chourey, Khushi Chouksey
semanticscholar   +1 more source

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

Food Frontiers, EarlyView.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh, Raz Abdulqadir, Indira Kumari Verma, Yashika Awasthi, Arun Ratn, Juhi Sharma, Manmeet Rawat, Megh Singh Dhakad, Jasbir Dalal, Yash Gupta, Bhisham Narayan Singh, Divakar Sharma   +11 more
wiley   +1 more source

Proteomic profile of human colon organoids: effects of a multi-mineral intervention alone and in the presence of pro-inflammatory and anti-inflammatory treatments

Frontiers in Gastroenterology
IntroductionAquamin, a multi-mineral product derived from fossilized red marine algae, has been shown to improve colon barrier structure and function.
Muhammad Nadeem Aslam, Shannon D. McClintock, Gillian Moraga, Daniyal M. Nadeem, Isabelle Harber, James Varani   +5 more
doaj   +1 more source

Red-Brown Urine Discolouration in Two Patients Taking Mesalamine [PDF]

, 2016
A 38-year-old male and a 36-year-old female experienced red-brown urine discolouration after 2 and 3 days, respectively, during the use of mesalamine for inflammatory bowel disease.
Florence van Hunsel, Tim Smeets
core   +1 more source

Drugs in focus: Budesonide and its role in paediatric gastrointestinal disorders

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Budesonide is a glucocorticoid with strong topical anti‐inflammatory properties and minimal systemic effects due to extensive first‐pass hepatic metabolism. It is designed for targeted delivery within the gastrointestinal (GI) tract and is available in oral and rectal formulations.
Sohail Aziz, Maria Giovanna Puoti, Amit Assa, Zrinjka Misak, Emmanuel Mas, Osvaldo Borrelli, Jernej Dolinšek, Javier Martin‐de‐Carpi, Isabelle Scheers, Christos Tzivinikos, Matjaž Homan, Caterina Strisciuglio   +11 more
wiley   +1 more source

One of the 5-aminosalicylates drug, mesalamine as a drug repurposing lead against breast cancer

Bulletin of the National Research Centre, 2022
Background Breast cancer is the world's second leading cause of death in women. The problem of chemoresistance in breast cancer is proving to be a challenge for researchers and several oncologists all around the world.
Dayanand Swami, Shafina Siddiqui, Urwashi Kumar, Shine Devarajan, Jyotirmoi Aich   +4 more
doaj   +1 more source

Ultrasound-mediated gastrointestinal drug delivery [PDF]

, 2015
available in PMC 2016 April 08There is a significant clinical need for rapid and efficient delivery of drugs directly to the site of diseased tissues for the treatment of gastrointestinal (GI) pathologies, in particular, Crohn’s and ulcerative colitis ...
Anderson, Daniel Griffith, Barman, Ross, Blankschtein, Daniel, Brugge, W. R., DiCiccio, Angela M, Langer, Robert S, Lauwers, Gregory Yves, Maa, Ruby C., Schoellhammer, Carl Magnus, Schroeder, Avraham Dror, Swiston, Albert J., Jr., Traverso, Carlo Giovanni, Zervas, Michael J.   +12 more
core   +1 more source

A case of autoimmune hepatitis in a patient with inflammatory bowel disease and significant lymphadenopathy in the porta hepatis

JPGN Reports, EarlyView.
Abstract The diagnosis of autoimmune hepatitis (AIH) is supported by the presence of elevated transaminases, hypergammaglobulinemia, liver biopsy consistent with AIH, and the presence of AIH autoantibodies. In this case presentation, we highlight the challenges associated with diagnosing AIH in a patient with inflammatory bowel disease (IBD) who ...
Benjamin J. Malamet, Shannon Joerger, Karen Caudill, Mai He, Juan Reyes Genere, Janis Stoll   +5 more
wiley   +1 more source