Results 61 to 70 of about 10,738 (252)
Allergy, EarlyView.We uncover an unprecedented role for IgE in CD. CD patients, regardless of allergic status and similar to allergic patients, display higher levels of circulating IgE+ and FcεRI+ immune cells, including pDCs, which are concomitant to fewer Tregs. In vitro experiments show that the anti‐IgE monoclonal antibody omalizumab restores the ability of pDCs from
Andrés de la Rocha‐Muñoz +11 more
wiley +1 more source
Second Korean guidelines for the management of ulcerative colitis [PDF]
, 2017 Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by a relapsing and remitting course. The direct and indirect costs of the treatment of UC are high, and the quality of life of patients is reduced, especially during ...
���������
core +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2017 Background & Aims: Mesalamine is a first-line drug for treatment of inflammatory bowel diseases (IBD). However, its mechanisms are not fully understood. CD4+ Foxp3+ regulatory T cells (Tregs) play a potential role in suppressing IBD.
Kyoko Oh-oka +11 more
doaj
Pharmaceutics, 2023 Drug targeting is necessary to deliver drugs to a specific site of action at a rate dictated by therapeutic requirements. The pharmacological action of a drug can thereby be optimised while minimising adverse effects.
Heba S. Abd-Ellah +3 more
doaj +1 more source
Alimentary Pharmacology &Therapeutics, Volume 61, Issue 8, Page 1276-1289, April 2025.Diets modelled on healthy eating guidelines, but differing in the content of emulsifiers available in the food supply, improved disease activity on sonographic criteria, Harvey‐Bradshaw Index and patient‐reported outcomes over 4 weeks in 24 patients with active Crohn's disease, with no differences according to the content of emulsifiers.
Jessica A. Fitzpatrick +7 more
wiley +1 more source
Clinical Pharmacology: Advances and Applications, 2012 Kavinderjit Nanda, Alan C MossCenter for Inflammatory Bowel Disease, BIDMC/Harvard Medical School, Boston, MA, USAAbstract: Ulcerative colitis (UC) is a chronic inflammatory disease of the colon that typically manifests as diarrhea, abdominal pain, and ...
Nanda K, Moss AC
doaj
Journal of Pediatric Gastroenterology and Nutrition, Volume 80, Issue 6, Page 967-978, June 2025.Abstract Objectives We determined the prevalence of anemia and its characteristics in children with newly diagnosed inflammatory bowel disease (IBD) and investigated its trend during follow‐up. Methods An observational, multicenter cohort study of IBD children with anemia at the diagnosis enrolled in the Italian Society of Pediatric Gastroenterology ...
Giulia D'Arcangelo +19 more
wiley +1 more source
Medications as a Source of Human Exposure to Phthalates. [PDF]
, 2012 Phthalates are a group of multifunctional chemicals used in consumer and personal care products, plastics, and medical devices. Laboratory studies show that some phthalates are reproductive and developmental toxicants.
Calafat, Antonia M +3 more
core +1 more source
Minimal change disease associated with balsalazide therapy for ulcerative colitis [PDF]
Journal of Nephropathology, 2019 Introduction: 5-aminosalicylic acid (5-ASA) compounds have been used in the management of ulcerative colitis for decades. Nephrotoxicity has been previously described in patients treated with 5-ASA compounds and usually manifests as interstitial ...
Ahmad M. Al-Taee +2 more
doaj +1 more source
Mucosal Healing in Ulcerative Colitis: A Comprehensive Review [PDF]
, 2017 Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by periods of remission and periods of relapse. Patients often present with symptoms such as rectal bleeding, diarrhea and weight loss, and may require hospitalization and even
A Bitton +104 more
core +1 more source