Results 61 to 70 of about 13,648 (298)

Recent advances in understanding and managing diverticulitis. [PDF]

open access: yes, 2018
In the past few decades, the increasing socioeconomic burden of acute diverticulitis (AD) has become evident, and with the growth of the population age, this significant economic impact will likely continue to rise. Furthermore, recent evidence showed an
Annibale, Bruno   +4 more
core   +2 more sources

Mesalamine induced hepatotoxicity. Is mesalamine safe?

open access: yesRevista Española de Enfermedades Digestivas
Mesalamine is a medication used widely in the treatment of patients with inflammatory bowel disease. Although mesalamine is considered safe, hepatotoxicity has been reported with an incidence of 0-4%. We present the clinical picture of a patient with hepatotoxicity due to mesalamine.
Javier, Pérez-Valenzuela   +3 more
openaire   +2 more sources

Treatment of diverticular disease: an update on latest evidence and clinical implications [PDF]

open access: yes, 2018
Background: Diverticular disease (DD) is a common condition, especially in Western countries. In about 80% of patients, colonic diverticula remain asymptomatic (diverticulosis), while approximately 20% of patients may develop abdominal symptoms ...
Annibale, B, Carabotti, M
core   +2 more sources

Management of paediatric ulcerative colitis, part 1: Ambulatory care—An updated evidence‐based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine   +24 more
wiley   +1 more source

Prevalence, predictors, and clinical consequences of medical adherence in IBD: How to improve it? [PDF]

open access: yes, 2009
Inflammatory bowel diseases (IBD) are chronic diseases with a relapsing-remitting disease course necessitating lifelong treatment. However, non-adherence has been reported in over 40% of patients, especially those in remission taking maintenance ...
Lakatos, Péter László
core   +2 more sources

Have we hit the JAK‐pot? Success of selective JAK 1 inhibitor following failure of pan‐JAK inhibitor in refractory pediatric ulcerative colitis

open access: yesJPGN Reports, EarlyView.
Abstract The treatment options available for pediatric ulcerative colitis (UC) are challenging due to few with Federal Drug Administration approval. Newer medications approved for adults include additional biologics with differing mechanisms of action and small molecule drugs, such as Janus kinase (JAK) inhibitors.
Jessica A. Black, Brad Pasternak
wiley   +1 more source

Tackling the Threat of Cancer Due to Pathobionts Producing Colibactin: Is Mesalamine the Magic Bullet?

open access: yesToxins, 2021
Colibactin is a genotoxin produced primarily by Escherichia coli harboring the genomic pks island (pks+ E. coli). Pks+ E. coli cause host cell DNA damage, leading to chromosomal instability and gene mutations.
Min Tang-Fichaux   +3 more
semanticscholar   +1 more source

Proteomic profile of human colon organoids: effects of a multi-mineral intervention alone and in the presence of pro-inflammatory and anti-inflammatory treatments

open access: yesFrontiers in Gastroenterology
IntroductionAquamin, a multi-mineral product derived from fossilized red marine algae, has been shown to improve colon barrier structure and function.
Muhammad Nadeem Aslam   +5 more
doaj   +1 more source

A Randomized Single Blind Parallel Group Study Comparing Monoherbal Formulation Containing Holarrhena antidysenterica Extract with Mesalamine in Chronic Ulcerative Colitis Patients

open access: yesAncient Science of Life, 2016
Background: Incidences of side effects and relapses are very common in chronic ulcerative colitis patients after termination of the treatment. Aims and Objectives: This study aims to compare the treatment with monoherbal formulation of Holarrhena ...
Sarika Johari, Tejal Gandhi
doaj   +1 more source

Mucosal Healing in Ulcerative Colitis: A Comprehensive Review [PDF]

open access: yes, 2017
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by periods of remission and periods of relapse. Patients often present with symptoms such as rectal bleeding, diarrhea and weight loss, and may require hospitalization and even
A Bitton   +104 more
core   +1 more source

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