Results 71 to 80 of about 13,648 (298)

Impact of biologic induction dose and concomitant drugs on anti‐drug antibody formation in a pediatric IBD cohort with high Hispanic representation

open access: yesJPGN Reports, EarlyView.
Abstract Objectives The use of biologic therapy is increasing in pediatric patients with inflammatory bowel disease (IBD). However, efficacy may be compromised by increased drug clearance and anti‐drug antibodies (ADAs). Historically, concomitant immunomodulator therapy (CIT) has been used to prevent ADA formation. Pediatric studies evaluating CIT have
Kenneth Grant   +3 more
wiley   +1 more source

Second Korean Guideline for the Management of Ulcerative Colitis [PDF]

open access: yes, 2017
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by a relapsing and remitting course. The direct and indirect costs of the treatment of UC are high, and the quality of life of patients is reduced, especially during ...
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core   +1 more source

Incidence and characteristics of pediatric patients with Crohn's disease undergoing surgery: A cross‐sectional study

open access: yesJPGN Reports, EarlyView.
ABSTRACT Objectives Despite biological treatments reducing the burden of pediatric inflammatory bowel disease, many patients still require surgery. Data on pediatric patient characteristics and surgical incidence are limited, often based on adult studies.
Hugo Gagnon   +6 more
wiley   +1 more source

Mesalamine Reduces Intestinal ACE2 Expression Without Modifying SARS-CoV-2 Infection or Disease Severity in Mice

open access: yesInflammatory Bowel Diseases, 2021
IntroductionCoronavirus Disease 2019 (COVID-19) is an ongoing public health crisis that has sickened or precipitated death in millions. The etiologic agent of COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), infects the intestinal ...
David M. Alvarado   +9 more
semanticscholar   +1 more source

The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial.

open access: yesPLoS ONE, 2014
UnlabelledThe anti-inflammatory agent, mesalamine (5-aminosalicylic acid) has been shown to decrease mucosal inflammation in ulcerative colitis. The effect of mesalamine in HIV-infected individuals, who exhibit abnormal mucosal immune activation and ...
Ma Somsouk   +15 more
doaj   +1 more source

Second Korean guidelines for the management of ulcerative colitis [PDF]

open access: yes, 2017
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by a relapsing and remitting course. The direct and indirect costs of the treatment of UC are high, and the quality of life of patients is reduced, especially during ...
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core   +1 more source

Evidence for a Modulatory Effect of a 12‐Week Pomegranate Juice Intervention on the Transcriptional Response in Inflammatory Bowel Disease Patients Reducing Fecal Calprotectin Levels: Findings From a Proof‐of‐Principle Study

open access: yesMolecular Nutrition &Food Research, EarlyView.
This study investigated how pomegranate juice affects inflammation in patients with inflammatory bowel disease who are currently in remission. After 12 weeks of drinking pomegranate juice, patients showed reduced markers of intestinal inflammation.
Ilaria Minato   +25 more
wiley   +1 more source

Water-in-Water Emulsion as a New Approach to Produce Mesalamine-Loaded Xylan-Based Microparticles

open access: yesApplied Sciences, 2019
The water-in-water emulsion method has been reported as a technique able to prepare microparticles without using harmful solvents. However, there are few reports showing the encapsulation of small molecules into microparticles produced within this ...
Bartolomeu S. Souza   +6 more
doaj   +1 more source

IBUS‐SAS Is a Highly Accurate Intestinal Ultrasound Score for Predicting Endoscopic Disease Activity in Ulcerative Colitis

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background The international bowel ultrasound group‐segmental activity score (IBUS‐SAS) is a validated tool with high interobserver agreement for accurately detecting disease activity in Crohn's disease (CD). Here, we addressed whether the IBUS‐SAS is also suitable to assess disease activity in ulcerative colitis (UC). Methods The IBUS‐SAS and
Sarah Fischer   +11 more
wiley   +1 more source

Enrichment of aqueous solubility and dissolution profile of mesalamine: In vitro evaluation of solid dispersion

open access: yesJournal of Pharmaceutical and Biological Sciences, 2021
The aim of the present study was to formulate solid dispersion (SD) of Mesalamine to enrich the aqueous solubility and dissolution rate. Mesalamine is used in the management of acute ulcerative colitis and for the prevention of relapse of active ...
A. Pawar   +4 more
semanticscholar   +1 more source

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