Results 71 to 80 of about 9,412 (255)

Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review

Avicenna Journal of Medicine, 2012
Inflammatory bowel disease and its various treatments may affect the kidney in several ways. Recently, case reports have been published documenting the development of nephrotic syndrome after the treatment for inflammatory bowel disease with 5 ...
Belal M Firwana, Rim Hasan, Walid Chalhoub, Mazen Ferwana, Jin-Yong Kang, Joshua Aron, Joseph Lieber   +6 more
doaj   +1 more source

Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in intestinal inflammation

Scientific Reports, 2019
Disruption of mucosal structure and barrier function contribute to the pathogenesis of inflammatory bowel disease (IBD). Efficacy of therapy in IBD is based on endoscopic mucosal healing, which occurs by a dynamic interplay of epithelial cell ...
V. Khare, A. Krnjic, A. Frick, C. Gmainer, Mario Asboth, K. Jimenez, M. Lang, M. Baumgartner, R. Evstatiev, C. Gasche   +9 more
semanticscholar   +1 more source

Clinical Trial: The Effects of Emulsifiers in the Food Supply on Disease Activity in Crohn's Disease: An Exploratory Double‐Blinded Randomised Feeding Trial

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 8, Page 1276-1289, April 2025.
Diets modelled on healthy eating guidelines, but differing in the content of emulsifiers available in the food supply, improved disease activity on sonographic criteria, Harvey‐Bradshaw Index and patient‐reported outcomes over 4 weeks in 24 patients with active Crohn's disease, with no differences according to the content of emulsifiers.
Jessica A. Fitzpatrick, Peter R. Gibson, Kirstin M. Taylor, Ellen J. Anderson, Antony B. Friedman, Zaid S. Ardalan, Rebecca L. Smith, Emma P. Halmos   +7 more
wiley   +1 more source

Optimizing the Use of Current Treatments and Emerging Therapeutic Approaches to Achieve Therapeutic Success in Patients with Inflammatory Bowel Disease

Gut and Liver, 2020
The current goal of inflammatory bowel disease (IBD) treatment is a symptom-free everyday life accompanied by mucosal healing with minimal use of corticosteroids.
Hiroshi Nakase
doaj   +1 more source

Pathophysiology of IBD as a Key Strategy for Polymeric Nanoparticle Development

Advanced Therapeutics, Volume 8, Issue 3, March 2025.
Polymeric nanoparticles are a promising approach for targeted drug delivery in case of patients with inflammatory bowel disease (IBD). IBD is a complex chronic gastrointestinal disease with compromised gastrointestinal barrier integrity, mucosal barrier alterations, altered cell surface receptor patterns, and oxidative stress. This review discusses how
Elena Gardey, Johannes C. Brendel, Andreas Stallmach   +2 more
wiley   +1 more source

Approach to anaemia in gastrointestinal disease: A position paper by the ESPGHAN Gastroenterology Committee

Journal of Pediatric Gastroenterology and Nutrition, Volume 80, Issue 3, Page 510-532, March 2025.
Approach to Anaemia in paediatric Gastrointestinal Disease Abstract Anaemia is a frequent consequence of many gastrointestinal (GI) diseases in children and it can even be the initial presenting symptom of underlying chronic GI disease. The definition of anaemia is age and gender‐dependent and it can be classified based on pathophysiology, red cell ...
Ilse Julia Broekaert, Amit Assa, Osvaldo Borrelli, Marco Deganello Saccomani, Matjaž Homan, Javier Martin‐de‐Carpi, Emmanuel Mas, Erasmo Miele, Zrinjka Misak, Sara Sila, Mike Thomson, Christos Tzivinikos, Jernej Dolinsek   +12 more
wiley   +1 more source

Maintaining remission in ulcerative colitis – role of once daily extended-release mesalamine

Drug Design, Development and Therapy, 2011
Lilliana Oliveira, Russell D CohenThe Department of Medicine, Section of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USAAbstract: The aminosalicylates (5-ASA; also referred to as mesalamine-based agents) are considered as first ...
Lilliana Oliveira, Russell D Cohen
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Meta‐Analysis: Exclusive Enteral Nutrition in Adults With Ulcerative Colitis

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 5, Page 756-775, March 2025.
This systematic review on exclusive enteral nutrition (EEN) in adults with ulcerative colitis (UC) found no significant difference in remission induction at 14 days. In acute severe UC, EEN combined with standard care did not affect colectomy or corticosteroid failure risk. Therapy discontinuation was low at 3%.
Matthew K. W. Chu, Alice S. Day, Lani Broad, Samuel P. Costello, Suzanne Edwards, Robert V. Bryant   +5 more
wiley   +1 more source

Periodic Table of Immunomodulatory Elements and Derived Two‐Dimensional Biomaterials

Advanced Science, Volume 12, Issue 6, February 10, 2025.
Two‐dimensional (2D) nanomaterials, possessing unique physiochemical properties, revolutionize the field of biomedical engineering to address critical diagnostic and therapeutic challenges. This review unveils the periodic table of 2D immunomodulatory elements, assessing synthesis, properties, immunomodulatory mechanisms and biocompatibility.
Alireza Rafieerad, Leena Regi Saleth, Soofia Khanahmadi, Ahmad Amiri, Keshav Narayan Alagarsamy, Sanjiv Dhingra   +5 more
wiley   +1 more source

A novel pH–enzyme-dependent mesalamine colon-specific delivery system

Drug Design, Development and Therapy, 2016
Lei Jin, Yi-cun Ding, Yu Zhang, Xiao-qing Xu, Qin Cao Department of Gastroenterology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China Abstract: The aim of the present study was to ...
Jin L, Ding Y, Zhang Y, Xu X, Cao Q
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