Results 11 to 20 of about 3,412 (160)

An Overview on the Hallucinogenic Peyote and Its Alkaloid Mescaline: The Importance of Context, Ceremony and Culture

open access: yesMolecules, 2023
Peyote (Lophophora williamsii) is a cactus that contains various biologically active alkaloids—such as pellotine, anhalonidine, hordenine and mescaline. Here, mescaline induces the psychoactive effects of peyote through the activation of the serotonin 5 ...
Amy Marisa Zimmermann-Klemd
exaly   +4 more sources

Acute dose-dependent effects of mescaline in a double-blind placebo-controlled study in healthy subjects [PDF]

open access: yesTranslational Psychiatry
Classic psychedelics have regained interest in research and therapy. Despite the long tradition of the human use of mescaline, modern data on its dose-dependent acute effects and pharmacokinetics are lacking. Additionally, its mechanism of action has not
Aaron Klaiber   +8 more
doaj   +3 more sources

Development of Japanese Versions of the 4-Item Mystical Experience Questionnaire and 7-Item Challenging Experience Questionnaire. [PDF]

open access: yesNeuropsychopharmacol Rep
The authorized Japanese versions of the MEQ‐4 and CEQ‐7 were developed in accordance with ISPOR good practice guidelines. These brief scales enable the rapid assessment of mystical and challenging experiences among Japanese speakers. ABSTRACT Introduction Interest in therapeutic applications of psychedelics has recently resurged.
Umemura F   +5 more
europepmc   +2 more sources

Psychedelic exposure in pregnancy: a scoping review to inform perinatal drug safety and clinical counseling [PDF]

open access: yesTherapeutic Advances in Drug Safety
Psychedelic and psychedelic-adjacent substances, including 3,4-methylenedioxymethamphetamine (MDMA) and classic serotonergic hallucinogens, are undergoing renewed therapeutic investigation and remain in non-medical use. Inadvertent exposure during early,
Ovie Martin Albert, Alexander Arthur
doaj   +2 more sources

Personalised Perception: The Effect of Personality on the Sensory Effects of Psychedelics. [PDF]

open access: yesDrug Alcohol Rev
ABSTRACT Introduction Psychedelics induce a wide range of sensory distortions and hallucinations (henceforth ‘distortions’). Yet, little is known about factors that influence the occurrence of certain distortions. Extra‐pharmacological variables including personality traits have been found to correlate with the occurrence of different subjective ...
Boardman A, Whelan J, Ward RD.
europepmc   +2 more sources

The complete chloroplast genome sequence of Lophophora diffusa [PDF]

open access: yesMitochondrial DNA. Part B. Resources
Lophophora diffusa is a psychoactive plant of Cactaceae, morphologically similar to the mescaline-rich Lophophora williamsii but with a distinct alkaloid profile, posing significant challenges for law enforcement.
Teng Zhang   +4 more
doaj   +2 more sources

Natural or artificial: An example of topographic spatial distribution analysis of mescaline in cactus plants by matrix-assisted laser desorption/ionization mass spectrometry imaging

open access: yesFrontiers in Plant Science, 2023
IntroductionDifferentiating whether plant products are natural or artificial is of great importance in many practical fields, including forensic science, food safety, cosmetics, and fast-moving consumer goods.
Jiaman Lin   +5 more
doaj   +1 more source

The association between naturalistic use of psychedelics and co-occurring substance use disorders

open access: yesFrontiers in Psychiatry, 2023
ObjectiveClassic psychedelics (LSD, psilocybin, and peyote/mescaline) have been used to support addiction treatment in a variety of contexts ranging from ceremonial use to clinical trials.
Jonina Rabinowitz   +6 more
doaj   +1 more source

Classic psychedelics do not affect T cell and monocyte immune responses

open access: yesFrontiers in Psychiatry, 2023
IntroductionClassic psychedelics have been shown to exert therapeutic potential for the treatment of various psychiatric disorders, neuropsychiatric diseases, and neuronal damage.
Deborah Rudin   +5 more
doaj   +1 more source

Henri Michaux's program for the psychedelic humanities

open access: yesFrontiers in Psychology, 2023
This article presents an analytical reading of the extraordinarily rich cultural production around drugs by the 20th-century French poet, writer, critic, and visual artist Michaux (1899–1984).
Oliver Davis
doaj   +1 more source

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