Results 61 to 70 of about 3,412 (160)
Scientific Reports, 2022 Opioid use disorder (OUD) is a major source of morbidity and mortality in the U.S. and there is a pressing need to identify additional treatments for the disorder.
Grant Jones +3 more
doaj +1 more source
The fourfold discovery of Mescaline (1896–1919) [PDF]
, 2019 This is an historical account of the pharmacological, chemical, and anthropological research concerning the molecular makeup of the peyote cactus (Lophophora williamsii) that laid the ground for Ernst Spaeth’s structural elucidation of mescaline as 3,4,5-
Ivo Gurschler
core +1 more source
, 2002 Archaeological investigations in northeast Mexico and Trans-Pecos, Texas have shown that the use of psychotropic drugs in this region goes back to around 8500 BC.
Bruhn, Jan G., +3 more
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British Journal of Pharmacology, Volume 183, Issue 14, Page 4058-4071, July 2026.Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito +6 more
wiley +1 more source
Frontiers in Human Neuroscience, 2016 Current theories in the framework of hierarchical predictive coding propose that positive symptoms of schizophrenia, such as delusions and hallucinations, arise from an alteration in Bayesian inference, the term inference referring to a process by which ...
Philipp Sterzer +3 more
doaj +1 more source
British Journal of Pharmacology, Volume 183, Issue 14, Page 4022-4047, July 2026.Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
International Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.ABSTRACT Objectives For English, the validated part of Psychedelic Experience Scale (PES48) is a four‐factor structure called the Mystical Experience Questionnaire (MEQ30). The other validated part of the PES48 consists of four more factors: two more mystical factors (paradoxicality and connectedness, which together with the MEQ30 form the MEQ40), and ...
Kurt Stocker +8 more
wiley +1 more source
Species variation in blood pressure responses to mescaline: Evidence of histamine release
, 1973 Mescaline sulfate infused iv in anesthetized dogs and cats produced dose-related systemic hypotension and bradycardia, whereas pressor responses were obtained in rats.
Goldstein, Frederick J. +1 more
core +1 more source
SACRED PLANTS AND MENTAL HEALTH IN LATIN AMERICA
Journal of Multidisciplinary Studies in Human Rights and Science, 2019 EN | Abstract: Sacred plants have a number of phenomena that revolve around their ritual and medicinal use, as well as being seen as carrying a bond with the sphere of the sacred.
Oscar Espin, Martin Díaz
doaj +1 more source
GC-MS and GC-MS/MS in PCI Mode Determination of Mescaline in Peyote Tea and in Biological Matrices
, 2012 Peyote, a cactus containing the hallucinogen mescaline, is used to induce altered states of consciousness in religious ceremonies or for recreational purpose. This study reports a case of an underage boy suspected of mescaline abuse. For this purpose, we
Marsili, Remo, Rossi, Riccardo
core +2 more sources