Results 81 to 90 of about 3,412 (160)

Novel, Unifying Mechanism for Mescaline in The Central Nervous System: Electrochemistry, Catechol Redox Metabolite, Receptor, Cell Signaling and Structure Activity Relationships [PDF]

open access: yes, 2009
A unifying mechanism for abused drugs has been proposed previously from the standpoint of electron transfer. Mescaline can be accommodated within the theoretical framework based on redox cycling by the catechol metabolite with its quinone counterpart ...
Peter Kovacic, Ratnasamy Somanathan
core   +1 more source

Cartoline dal paradiso : drogue, invasion et autodestruction chez Elsa Morante

open access: yesCahiers d’Études Italiennes
The importance of drugs as a theme in the second half of Elsa Morante’s work is rarely emphasized. Beginning with the author’s existential and political turn in the 1960s, a decade that saw her experiment with a series of sedatives and psychedelics ...
Marie Fabre
doaj   +1 more source

Serotonergic hallucinogens and recognition of facial emotion expressions: a systematic review of the literature

open access: yesTherapeutic Advances in Psychopharmacology, 2019
Background: Recognition of emotions in facial expressions (REFE) is a key aspect of social cognition. Anxiety and mood disorders are associated with deficits in REFE, and anxiolytics and antidepressants reverse these deficits.
Juliana M. Rocha   +6 more
doaj   +1 more source

Psychedelics as novel therapeutic agents for chronic pain: mechanisms and future perspectives

open access: yesExploration of Neuroscience
Chronic neuropathic pain is a significant public health issue affecting an estimated 1.5 billion individuals worldwide. The mechanisms underlying chronic pain are multifaceted and not fully understood.
Bushra Yasin   +3 more
doaj   +1 more source

C-(4,5,6-Trimethoxyindan-1-yl)methanamine:  A Mescaline Analogue Designed Using a Homology Model of the 5-HT2A Receptor

open access: yes, 2016
A conformationally restricted analogue of mescaline, C-(4,5,6-trimethoxyindan-1-yl)-methanamine, was designed using a 5-HT2A receptor homology model. The compound possessed 3-fold higher affinity and potency than and efficacy equal to that of mescaline ...
James J. Chambers (222285)   +6 more
core   +1 more source

Benjamin e il gioco dell'oppio [PDF]

open access: yesKaiak, 2019
In the late, roaring Twenties and the early, uncanny Thirties of the 20th Century, German philosopher and essayist Walter Benjamin went through a considerable series of experiments with drugs.
Massimo Palma
doaj  

Sartre et l'expérimentation de la mescaline dans le contexte de la psychopathologie française des années 1930

open access: yes, 2021
L'expérimentation de la mescaline par Sartre est aussi célèbre que mal connue. Il convient de faire ressortir le contexte psychopathologique particulier dans lequel le psychiatre Daniel Lagache devait également avoir une motivation théorique pour diriger
Dassonneville, Gautier
core  

Methods for GC/MS Analysis of the Most Commonly Seized Drugs of Abuse and Their Metabolites in Biological Samples

open access: yesChemosensors
Gas chromatography with mass spectrometry (GC-MS) is a common analytical technique used for identifying and quantifying drugs of abuse, as well as their metabolites, extracted from biological samples. Depending on the properties of the analyzed compounds,
Ivan Kojić   +7 more
doaj   +1 more source

Synthesis of a Tricyclic Mescaline Analogue by Catalytic C−H Bond Activation

open access: yes, 2016
A tetrahydrobis(benzofuran) mescaline analogue has been prepared in six steps and 38% overall yield from (4‘-O-methyl)methyl gallate. The key step in this synthesis is a tandem cyclization reaction via directed C−H activation followed by olefin ...
Robert G. Bergman (1323120)   +2 more
core   +2 more sources

Minorities’ Diminished Psychedelic Returns: Gender, Perceived Stigma, and Distress

open access: yesPsychoactives
Because psychedelics have been found to increase psychological traits like openness, mental flexibility, and interpersonal perceptiveness, some researchers believe that psychedelics could help individuals cope with the psychological effects of ...
Sean Matthew Viña
doaj   +1 more source

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