Results 271 to 280 of about 26,579 (349)

Unraveling the Role of WDR91: Case Report of a Previously Unrecognized Clinical Entity

Clinical Genetics, Volume 109, Issue 1, Page 176-180, January 2026.
A novel case is herein described to expand the genetic and clinical spectrum of WDR91 and characterize a previously unrecognized autosomal recessive neurodevelopmental disorder. WDR91 deficiency results in neuronal loss, cortical thinning, and impaired brain development.
Nikolaos M. Marinakis, Afrodite Kampouraki, Danai Veltra, Faidon‐Nikolaos Tilemis, Maria Vasilopoulou, Aikaterini Dokou, Elissavet Georgiadou, Euthalia Karavergou, Maria Christolouka, Alexis Alexopoulos, Dimitra Kirillidi, Maria Goudesidou, Konstantina Kosma, Christalena Sofocleous, Periklis Makrythanasis   +14 more
wiley   +1 more source

Modified specific components of conspecific advertisement calls influence behavioral and neural responses in music frogs. [PDF]

Commun Biol
Qing T, Shen D, Fan Y, Shi S, Lu L, Wu Y, Fang G.   +6 more
europepmc   +1 more source

Evaluation of leptin treatment on maintenance of body weight loss in diet‐induced obese mice

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 401-416, January 2026.
Abstract Aims To evaluate the therapeutic potential of leptin treatment for weight loss maintenance preclinically, through a systematic evaluation of leptin efficacy (a) following a period of weight loss stability (as in published clinical studies), and (b) across a range of circulating leptin concentrations achieved through a variety of different ...
Danna M. Breen, Rocío M. Saavedra‐Peña, Stephanie Joaquim, Jimmy Kong, Ryan Reese, J. Brent Kuzmiski, John C. Stansfield, Rhys Jones, Kendra K. Bence, V. Margaret Jackson   +9 more
wiley   +1 more source

Extended Technical and Clinical Validation of Deep Learning-Based Brainstem Segmentation for Application in Neurodegenerative Diseases. [PDF]

Hum Brain Mapp
Gesierich B, Sander L, Pirpamer L, Meier DS, Ruberte E, Amann M, Sinnecker T, Huck A, de Leeuw FE, Maillard P, Moy S, Helmer KG, MarkVCID Consortium, Levin J, Höglinger GU, PROMESA Study Group, Kühne M, Bonati LH, Kuhle J, Cattin P, Granziera C, Schlaeger R, Duering M.   +22 more
europepmc   +1 more source

The prion protein gene:a role in mouse embryogenesis? [PDF]

, 1992
Hope, J, Kaufman, M H, Manson, J, McBride, P, Thomson, V, West, J D   +5 more
core  

Novel Magnetic Resonance Imaging Findings of Bilaterally Symmetrical Lesions in a Dog With Concomitant Granulomatous Meningoencephalitis and Necrotizing Encephalitis

Veterinary Radiology &Ultrasound, Volume 67, Issue 1, January 2026.
ABSTRACT A 3‐year‐old, female neutered Bichon Frise was presented with a 2‐day history of behavioral changes and ataxia. The neurological examination was consistent with diffuse forebrain involvement, with left lateralization. An MRI study identified bilaterally symmetrical T2W/T2 fluid‐attenuated inversion recovery (T2‐FLAIR) hyperintense, T1W ...
Tessa Victoria Procter, Jacqueline Poldy, Adrian William Philbey, Sumari Dancer, Callum Nicholas Atkins, Megan Elizabeth Madden   +5 more
wiley   +1 more source

Open isthmus and lambda sign of early Joubert syndrome: elucidating development of molar tooth sign. [PDF]

Ultrasound Obstet Gynecol
Pooh RK, Takeda M, Itoh K, Yoshimatsu J, Ogo K, Machida M, Ohashi H, Shimokawa O.   +7 more
europepmc   +1 more source

Time‐Dependent Therapeutic Effect of S‐Ketamine on PTSD Mediated by VTA‐OFC Dopaminergic Neurocircuit

Advanced Science, Volume 12, Issue 46, December 11, 2025.
This study reveals that early rather than late administration of S‐ketamine can ameliorate PTSD symptoms. This phenomenon is attributed to reversing the progressive inhibition of VTADA neurons and the function of VTADA‐OFC circuit following stress. Targeted stimulation of the OFC by TI‐NIBS to enhance DA release effectively extends the therapeutic time
Ye Wang, Lei Liu, Jinghao Wang, Jiannan Li, Huiming Li, Rui Wang, Hui Wang, Min Wang, Quanying Liu, Zhongmin Fan, Yunyun Zhang, Xinxin Zhang, Dan Wang, Sa Wang, Rou Xue, Jindong Mao, Min Cai, Pengfei Wei, Hailong Dong, Yumei Wu, Guangchao Zhao   +20 more
wiley   +1 more source

Changes in neural progenitor lineage composition during astrocytic differentiation of human iPSCs. [PDF]

Elife
Li Z, Cardo LF, Rokicki M, Monzón-Sandoval J, Volpato V, Wessely F, Webber C, Li M.   +7 more
europepmc   +1 more source

Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck, Typhaine Dupont, Rupert Andrews Cavanagh, Olivier Postal, Jérôme Bourien, Jean‐Luc Puel, Nicolas Michalski, Boris Gourévitch   +7 more
wiley   +1 more source