Results 281 to 290 of about 32,053 (378)

Neurogenesis and neuronal migration of dopaminergic neurons during mesencephalon development in mice

, 2018
Mun-ki Kim, Si-Joon Lee, Anju Vasudevan, Chung‐Kil Won   +3 more
openalex   +2 more sources

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Frame-based stereotactic biopsies of brainstem lesions - Monocentric comparison of the transfrontal and the suboccipital-transcerebellar approach over a 16-year period. [PDF]

Neurosurg Rev
Kaes M, Neumann JO, Beynon C, Naser PV, Kiening K, Krieg SM, Jakobs M.   +6 more
europepmc   +1 more source

The prion protein gene:a role in mouse embryogenesis? [PDF]

, 1992
Hope, J, Kaufman, M H, Manson, J, McBride, P, Thomson, V, West, J D   +5 more
core  

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, Volume 13, Issue 7, 3 February 2026.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Mapping Bornavirus encephalitis-A comparative study of viral spread and immune response in human and animal dead-end hosts. [PDF]

PLoS Pathog
Vollmuth Y, Jungbäck N, Grochowski P, Mögele T, Stark L, Zarrabi NS, Schlegel J, Schaller T, Märkl B, Matiasek K, Liesche-Starnecker F.   +10 more
europepmc   +1 more source

High‐mobility Group Protein 1/ Receptor for Advanced Glycation End Products/ Nuclear Factor‐κB Signalling Pathway Contributes to the Pathogenic Process of Striatal Neuron Impairment in the Rat Model of Parkinson's Disease

Brain and Behavior, Volume 16, Issue 2, February 2026.
In Parkinson's disease, the death of dopamine neurons in the substantia nigra, resulting in a decrease in dopamine levels in the striatum. This leads to striatal damage through the HMGB1/RAGE/NF‐κB signaling pathway, thereby inducing motor and cognitive dysfunction.
Yaofeng Zhu, Zean Du, Liping Sun, Ziyun Huang, Linju Jia, Tao Chen, Xuefeng Zheng, Wanlong Lei   +7 more
wiley   +1 more source

Prolonged Corticosteroid Use in the Treatment of Tuberculous Meningoencephalitis: A Case Report. [PDF]

Medicina (Kaunas)
Holstroma A, Balodis A, Brokans A, Viksna A.   +3 more
europepmc   +1 more source

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

Brain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu, Biniam Moges Eskeziyaw   +1 more
wiley   +1 more source

Spontaneous generation of diverse recombinant prion strains: sulfated glycan cofactors facilitate strain emergence but do not determine specific strain properties. [PDF]

Acta Neuropathol Commun
Lorenzo NL, Eraña H, Vidal E, Charco JM, Parga L, Díaz-Domínguez CM, Veiga S, Bravo S, Giler S, Geijo M, Requena JR, Castilla J.   +11 more
europepmc   +1 more source