Results 11 to 20 of about 1,352,090 (296)
Effects of Mesenchymal Stem Cell-Derived Exosomes on Autoimmune Diseases [PDF]
Frontiers in Immunology, 2021 Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have been demonstrated in preclinical studies and trials of inflammatory and autoimmune diseases.
Ziwei Shen +5 more
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Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials
Stem cell research & therapeutics, 2023 Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their robust immunomodulatory and regenerative properties. Their paracrine activity is one of the most important features that contribute to their efficacy. Recently, it
A. Lotfy +2 more
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Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review
Stem cell research & therapeutics, 2022 The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide consideration because of their immense potential for immunomodulation and their therapeutic function in tissue regeneration.
Ria Margiana +12 more
semanticscholar +1 more source
Molecular Cancer, 2022 Mesenchymal stem cells (MSCs) are multipotent stromal cells that can be obtained from various human tissues and organs. They can differentiate into a wide range of cell types, including osteoblasts, adipocytes and chondrocytes, thus exhibiting great ...
Zhengjun Lin +5 more
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Advances in mesenchymal stem cell exosomes: a review
Stem cell research & therapeutics, 2021 Stem cells can be used for regenerative medicine and as treatments for disease. The application of tissue engineering-related transplantation, stem cells, and local changes in the microenvironment is expected to solve major medical problems.
Yaya Tang, Yan Zhou, Hong-jun Li
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Stem Cells Translational Medicine, 2021 Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to be popular based on progressive accumulation of preclinical mechanistic evidence.
Li-Tzu Wang +4 more
semanticscholar +1 more source
Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]
PLoS ONE, 2013 Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova +2 more
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Stem Cell Research & Therapy, 2020 Background During development, excessive osteogenic differentiation of mesenchymal progenitor cells (MPC) within the cranial sutures can lead to premature suture fusion or craniosynostosis, leading to craniofacial and cognitive issues.
Clara Pribadi +5 more
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Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy
Cellular and Molecular Life Sciences, 2020 Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of various diseases. The therapeutic potential of MSCs is attributed to complex cellular and molecular mechanisms of action including differentiation into multiple cell ...
Xingliang Fan +3 more
semanticscholar +1 more source
Annals of Medicine, 2005 About 40 years ago Friedenstein described stromal cells in the bone marrow that were spindle shaped and proliferate to form colonies. These cells attach to plastic and are able to differentiate under defined in vitro conditions into multiple cell types present in many different tissues, e.g. osteoblasts, chondroblasts, adipocytes, etc.
Mark F Pittenger +4 more
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