Results 11 to 20 of about 475,787 (198)

Stem cell therapy in renal diseases [PDF]

open access: yesJournal of Bioscience and Applied Research, 2022
Objective: to evaluate the stem cell in treating renal diseases. To evaluate the effect of stem cells on renal cell apoptosis and necroptosis. Background: The use of stem cells is the hope for all patients with end-stage renal diseases.
Khalil Alhalfawy   +4 more
doaj   +1 more source

Pharmacological targeting of KDM6A and KDM6B, as a novel therapeutic strategy for treating craniosynostosis in Saethre-Chotzen syndrome

open access: yesStem Cell Research & Therapy, 2020
Background During development, excessive osteogenic differentiation of mesenchymal progenitor cells (MPC) within the cranial sutures can lead to premature suture fusion or craniosynostosis, leading to craniofacial and cognitive issues.
Clara Pribadi   +5 more
doaj   +1 more source

Mesenchymal stem cells

open access: yesAnnals of Medicine, 2005
About 40 years ago Friedenstein described stromal cells in the bone marrow that were spindle shaped and proliferate to form colonies. These cells attach to plastic and are able to differentiate under defined in vitro conditions into multiple cell types present in many different tissues, e.g. osteoblasts, chondroblasts, adipocytes, etc.
Mark F Pittenger   +4 more
openaire   +3 more sources

Differential marker expression by cultures rich in mesenchymal stem cells [PDF]

open access: yes, 2013
Background: Mesenchymal stem cells have properties that make them amenable to therapeutic use. However, the acceptance of mesenchymal stem cells in clinical practice requires standardized techniques for their specific isolation.
Adra, Chaker   +12 more
core   +1 more source

Influencing the secretion of myogenic factors from mesenchymal stem cells. [PDF]

open access: yes, 2014
Mounting evidence indicates that the regenerative effect of mesenchymal stem cells in skeletal muscle is related to the secretion of factors that stimulate resident myogenic cells.
Smith, Lucas R
core   +1 more source

Mesenchymal Stem Cells

open access: yesExperimental Biology and Medicine, 2001
Within the bone marrow stroma there exists a subset of nonhematopoietic cells referred to as mesenchymal stem or mesenchymal progenitor cells. These cells can be ex vivo expanded and induced, either in vitro or in vivo, to terminally differentiate into osteoblasts, chondrocytes, adipocytes, tenocytes, myotubes, neural cells, and hematopoietic ...
Minguell, JJ, Erices, A, Conget, P
openaire   +6 more sources

Milieu-adopted in vitro and in vivo differentiation of mesenchymal tissues derived from different adult human CD34-negative progenitor cell clones [PDF]

open access: yes, 2005
Adult mesenchymal stem cells with multilineage differentiation potentially exist in the bone marrow, but have also been isolated from the peripheral blood.
Huss, R.   +4 more
core   +1 more source

Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination

open access: yesEpigenetics & Chromatin, 2019
Background The 5 hydroxymethylation (5hmC) mark and TET DNA dioxygenases play a pivotal role in embryonic stem cell differentiation and animal development.
Dimitrios Cakouros   +6 more
doaj   +1 more source

Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications [PDF]

open access: yes, 2017
Mesenchymal stem cells (MSCs) are attracting growing interest by the scientific community due to their huge regenerative potential. Thus, the plasticity of MSCs strongly suggests the utilization of these cells for regenerative medicine applications.
Codispoti, Bruna   +6 more
core   +2 more sources

The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Bone marrow microenvironment contains cellular and acellular compartments. The cellular compartment includes hematopoietic stem cells, mesenchymal stem cells and some other stromal cell types, while the acellular compartment is composed of scaffold ...
Mahshid Saleh   +4 more
doaj   +1 more source

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