Results 11 to 20 of about 1,146,077 (364)
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
Scientific Reports, 2020 Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro +7 more
doaj +1 more source
Stem cell therapy in renal diseases [PDF]
Journal of Bioscience and Applied Research, 2022 Objective: to evaluate the stem cell in treating renal diseases. To evaluate the effect of stem cells on renal cell apoptosis and necroptosis. Background: The use of stem cells is the hope for all patients with end-stage renal diseases.
Khalil Alhalfawy +4 more
doaj +1 more source
Stem Cell Research & Therapy, 2020 Background During development, excessive osteogenic differentiation of mesenchymal progenitor cells (MPC) within the cranial sutures can lead to premature suture fusion or craniosynostosis, leading to craniofacial and cognitive issues.
Clara Pribadi +5 more
doaj +1 more source
Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]
PLoS ONE, 2013 Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova +2 more
doaj +1 more source
Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy
Cellular and Molecular Life Sciences, 2020 Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of various diseases. The therapeutic potential of MSCs is attributed to complex cellular and molecular mechanisms of action including differentiation into multiple cell ...
Xingliang Fan +3 more
semanticscholar +1 more source
Mesenchymal stem cell perspective: cell biology to clinical progress
npj Regenerative Medicine, 2019 The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell population of multipotential stem/progenitor cells commonly referred to as mesenchymal stem cells, multipotential stromal cells, mesenchymal stromal cells, and ...
M. Pittenger +5 more
semanticscholar +1 more source
Experimental Biology and Medicine, 2001 Within the bone marrow stroma there exists a subset of nonhematopoietic cells referred to as mesenchymal stem or mesenchymal progenitor cells. These cells can be ex vivo expanded and induced, either in vitro or in vivo, to terminally differentiate into osteoblasts, chondrocytes, adipocytes, tenocytes, myotubes, neural cells, and hematopoietic ...
Minguell, JJ, Erices, A, Conget, P
openaire +6 more sources
Immunobiology of mesenchymal stem cells [PDF]
Cell Death & Differentiation, 2013 Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively expanded in vitro. Although their true in situ properties and biological functions remain to be elucidated, these in vitro expanded cells have been shown to possess potential to differentiate into specific cell lineages.
Ma, S +5 more
openaire +2 more sources
Mesenchymal Stem Cell Therapy for COVID-19: Present or Future
Stem Cell Reviews and Reports, 2020 “COVID-19” is the word that certainly isn’t forgotten by everybody who lives in the first half of the twenty-first century. COVID-19, as a pandemic, has led many researchers from different biomedical fields to find solutions or treatments to manage the ...
A. Golchin +2 more
semanticscholar +1 more source
Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination
Epigenetics & Chromatin, 2019 Background The 5 hydroxymethylation (5hmC) mark and TET DNA dioxygenases play a pivotal role in embryonic stem cell differentiation and animal development.
Dimitrios Cakouros +6 more
doaj +1 more source