Results 11 to 20 of about 561,805 (383)

Mesenchymal Stem Cells [PDF]

Cell Transplantation, 2011
Stem cells have two features: the ability to differentiate along different lineages and the ability of self-renewal. Two major types of stem cells have been described, namely, embryonic stem cells and adult stem cells. Embryonic stem cells (ESC) are obtained from the inner cell mass of the blastocyst and are associated with tumorigenesis, and the use ...
Dah-Ching Ding, Woei Cherng Shyu, Shinn Zong Lin   +2 more
openaire   +5 more sources

Mesenchymal stem cells and their microenvironment

Stem Cell Research & Therapy, 2022
AbstractMesenchymal stem cells (MSCs), coming from a wide range of sources, have multi-directional differentiation ability. MSCs play vital roles in immunomodulation, hematopoiesis and tissue repair. The microenvironment of cells often refers to the intercellular matrix, other cells, cytokines and humoral components.
Jiaxi Liu, Jinfang Gao, Zixie Liang, Chong Gao, Qing Niu, Fengping Wu, Liyun Zhang   +6 more
openaire   +3 more sources

Mesenchymal Stem Cells [PDF]

Experimental Biology and Medicine, 2001
Within the bone marrow stroma there exists a subset of nonhematopoietic cells referred to as mesenchymal stem or mesenchymal progenitor cells. These cells can be ex vivo expanded and induced, either in vitro or in vivo, to terminally differentiate into osteoblasts, chondrocytes, adipocytes, tenocytes, myotubes, neural cells, and hematopoietic ...
Minguell, JJ, Erices, A, Conget, P
openaire   +6 more sources

Immunobiology of mesenchymal stem cells [PDF]

Cell Death & Differentiation, 2013
Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively expanded in vitro. Although their true in situ properties and biological functions remain to be elucidated, these in vitro expanded cells have been shown to possess potential to differentiate into specific cell lineages.
Ying Wang, S Ma, Wenzhao Li, Ningxia Xie, B Yuan, Yufang Shi   +5 more
openaire   +3 more sources

Human mesenchymal stem cells [PDF]

Cell Proliferation, 2021
AbstractMesenchymal stem cells (MSCs) have attracted great interest for cell therapy and tissue regeneration due to their self‐renewal capacity, multipotency and potent immunomodulatory effects on immune cells. However, heterogeneity of MSCs has become a prominent obstacle to limit their translation into practice, as cells from different tissue sources
Xiaoyong Chen, Jing Huang, Jun Wu, Jie Hao, Boqiang Fu, Ying Wang, Bo Zhou, Tao Na, Jun Wei, Yong Zhang, Qiyuan Li, Shijun Hu, Jiaxi Zhou, Junying Yu, Zhaohui Wu, Huanxin Zhu, Jiani Cao, Lei Wang, Yaojin Peng, Lingmin Liang, Aijin Ma, Yu Zhang, Tongbiao Zhao, Andy Peng Xiang   +23 more
openaire   +2 more sources

Influencing the secretion of myogenic factors from mesenchymal stem cells. [PDF]

, 2014
Mounting evidence indicates that the regenerative effect of mesenchymal stem cells in skeletal muscle is related to the secretion of factors that stimulate resident myogenic cells.
Smith, Lucas R
core   +1 more source

Osteostatin potentiates the bioactivity of mesoporous glass scaffolds containing Zn2+ ions in human mesenchymal stem cell cultures [PDF]

Acta Biomaterialia. 89 (2019) 359-371, 2021
There is an urgent need of biosynthetic bone grafts with enhanced osteogenic capacity. In this study, we describe the design of hierarchical meso-macroporous 3D-scaffolds based on mesoporous bioactive glasses (MBGs), enriched with the peptide osteostatin and Zn2+ ions, and their osteogenic effect on human mesenchymal stem cells (hMSCs) as a preclinical
arxiv   +1 more source

Differential marker expression by cultures rich in mesenchymal stem cells [PDF]

, 2013
Background: Mesenchymal stem cells have properties that make them amenable to therapeutic use. However, the acceptance of mesenchymal stem cells in clinical practice requires standardized techniques for their specific isolation.
Adra, Chaker, Al-Alwan, Monther, Al-Humaidan, Hind, Al-Mazrou, Amer, Alaiya, Ayodele, Gaafar, Ameera, Ghebeh, Hazem, Kanaan, Imaduddin, Pradez, Christian Benedict, Pulicat, Manogaran S, Shinwari, Zakia, Sleiman, Ghida Majed, Wetzig, Andrew   +12 more
core   +1 more source

Mesenchymal stem cells and JIA [PDF]

Pediatric Rheumatology, 2011
Background Mesenchymal stem cells (MSC) are adult stem cells present in bone marrow (BM), fat and in many other tissues. MSC have strong immunosuppressive qualities in vitro. The immunosuppression seems to work both by paracrine action and cell-cell contact. MSC inhibit NKcells, B-cells, dendritic cells, Th1-cells and activate regulatory T-cells.
W. Kuis, Ineke Slaper-Cortenbach, Berent J. Prakken, NM Wulffraat, Joost F Swart, S de Roock, Anton C.M. Martens, Frans M. A. Hofhuis   +7 more
openaire   +3 more sources

The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells [PDF]

Advanced Pharmaceutical Bulletin, 2015
Bone marrow microenvironment contains cellular and acellular compartments. The cellular compartment includes hematopoietic stem cells, mesenchymal stem cells and some other stromal cell types, while the acellular compartment is composed of scaffold ...
Mahshid Saleh, karim Shamsasanjan, Aliakbar Movassaghpourakbari, Parvin Akbarzadehlaleh, Zahra Molaeipour   +4 more
doaj   +1 more source