Results 41 to 50 of about 289,571 (169)

Alginate-encapsulated brain-derived neurotrophic factor–overexpressing mesenchymal stem cells are a promising drug delivery system for protection of auditory neurons

Journal of Tissue Engineering, 2020
The cochlear implant outcome is possibly improved by brain-derived neurotrophic factor treatment protecting spiral ganglion neurons. Implantation of genetically modified mesenchymal stem cells may enable the required long-term brain-derived neurotrophic ...
Jana Schwieger, Anika Hamm, Michael M. Gepp, André Schulz, Andrea Hoffmann, Thomas Lenarz, Verena Scheper   +6 more
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Introduce Characteristic, Types and Functional Mechanism of Adjuvants as a Biologic Complement [PDF]

Journal of Advanced Biomedical Sciences, 2019
The widespread use of effective vaccines against infectious diseases has been one of the most important public health progresses in the 21st century.
Tahereh Zarei Taher, Ali Kowsari, Mohsen Sheykhhasan, Hamed Manoochehri, Naser Kalhor, Leila Naserpour   +5 more
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ADMINISTRATION OF BONE MARROW DERIVED MESENCHYMAL STEM CELLS MODULATE TLR EXPRESSION DURING LIVER REGENERATION

Trakya University Journal of Natural Sciences, 2019
Liver cell transplantation is a powerful alternative to orthotopic cell transplantation in the treatment of liver failures. Recently, considerable effort is being channeled to understand the nature and kinetics of directing stem cells to effectively ...
İhsan Gursel, Kamil Can Akçalı, Burcu İnsal, Hande Kocak, Zeynep Tokcaer-keskin   +4 more
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Effect of Platelet-rich Plasma and Mesenchymal Stem Cells as Two Biological Alternatives in Rotator Cuff Injury Treatment: A Mini-review

Research in Molecular Medicine, 2019
The rotator cuff injury is caused by significant damage by trauma or other factors and currently recognized as a prevalent orthopedic problem. Many clinical procedures have been proposed to reduce the complication of rotator cuff injury with varying ...
Mohsen Sheykhhasan, Hamed Manoochehri, Pouria Samadi, Reza Fotouhi-Ardakani, Naser Kalhor   +4 more
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Induced pluripotent stem cell–derived mesenchymal stem cells enhance acellular nerve allografts to promote peripheral nerve regeneration by facilitating angiogenesis

Neural Regeneration Research
Previous research has demonstrated the feasibility of repairing nerve defects through acellular allogeneic nerve grafting with bone marrow mesenchymal stem cells. However, adult tissue–derived mesenchymal stem cells encounter various obstacles, including
Fan-Qi Meng, Chao-Chao Li, Wen-Jing Xu, Jun-Hao Deng, Yan-Jun Guan, Tie-Yuan Zhang, Bo-Yao Yang, Jian Zhang, Xiang-Ling Li, Feng Han, Zhi-Qi Ren, Shuai Xu, Yan Liang, Wen Jiang, Jiang Peng, Yu Wang, Hai-Ying Liu   +16 more
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Role of miRNAs from mesenchymal stem cell–derived extracellular vesicles in neuroinflammation and behavioral impairments induced by chronic alcohol consumption in female mice

Neural Regeneration Research
Mesenchymal stem cell–derived extracellular vesicles have emerged as a promising form of regenerative and immunomodulatory therapy; indeed, micro (mi)RNAs contained within mesenchymal stem cell–derived extracellular vesicles modulate target gene ...
Susana Mellado, Najoua Touahri, Sandra Montagud-Romero, Carla Perpiñá-Clérigues, Francisco García-García, Victoria Moreno-Manzano, Consuelo Guerri, Marta Rodríguez-Arias, María Pascual   +8 more
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Comments on: “Mesenchymal stem cells transplantation for perianal fistulas: a systematic review and meta-analysis of clinical trials”

Stem Cell Research & Therapy, 2023
The meta-analysis by Wang et al. (Stem Cell Res Ther 14(1):103, 2023) aims to explore whether mesenchymal stem cells are effective for perianal fistulas.
Fang Cheng
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Mesenchymal stem cells: From stem cells to sarcomas [PDF]

Cell Biology International, 2016
Abstract Mesenchymal stem cells (MSCs) have garnered vast interests in clinical settings, especially in regenerative medicine due to their unique properties—they are reliably isolated and expanded from various tissue sources; they are able to differentiate into mesodermal tissues such as bones,
Lye, Kwan Liang, Nordin, Norshariza, Vidyadaran, Sharmili, Karuppiah, Thilakavathy   +3 more
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Mesenchymal Stem Cells Immunosuppressed IL-22 in Patients with Immune Thrombocytopenia via Soluble Cellular Factors

Journal of Immunology Research, 2015
Mesenchymal stem cells are immunoregulation cells. IL-22 plays an important role in the pathogenesis of immune thrombocytopenia. However, the effects of mesenchymal stem cells on IL-22 production in patients with immune thrombocytopenia remain unclear ...
Mei Wu, Hongfeng Ge, Shue Li, Hailiang Chu, Shili Yang, Xiaoxing Sun, Zhenxia Zhou, Xiongpeng Zhu   +7 more
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Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice

Journal of Neuroinflammation, 2018
Background Ischemic stroke induced matrixmetallo-proteinase-9 (MMP-9) upregulation, which increased blood-brain barrier permeability. Studies demonstrated that mesenchymal stem cell therapy protected blood-brain barrier disruption from several ...
Zhuo Cheng, Liping Wang, Meijie Qu, Huaibin Liang, Wanlu Li, Yongfang Li, Lidong Deng, Zhijun Zhang, Guo-Yuan Yang   +8 more
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