Results 251 to 260 of about 556,462 (362)

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

A first-in-human pilot study of Wharton's jelly-derived mesenchymal stem cell injection for urethral stricture: safety and preliminary efficacy. [PDF]

World J Urol
Ortac M, Ozervarli MF, Tantekin SA, Ergul RB, Ates Y, Aydinoglu AT, Aydin R, Tonyali S, Atala A.   +8 more
europepmc   +1 more source

Bone marrow-derived mesenchymal stem cells inhibit the proliferation of hepatic stellate cells by inhibiting the transforming growth factor β pathway

, 2015
LI-TING ZHANG, Xue-Qin Fang, Qing‐Feng Chen, Hong Chen, Ping Xiao, Xuebin Peng, SHENG-XIANG ZHANG, JUN-FENG LI, Xiaorong Mao   +8 more
openalex   +2 more sources

Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells

Advanced Science, EarlyView.
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale, Luca Messina, Valeria Panzetta, Stefania Saporito, Costantino Menna, Maurizio Ventre, Paolo A. Netti   +6 more
wiley   +1 more source

Advancing mesenchymal stem cell therapy for kidney diseases in companion animals: from mechanisms to clinical application. [PDF]

Front Vet Sci
Yu Y, Wang Y, Mu Y, Wang S, Zhang X, Song Y.   +5 more
europepmc   +1 more source

Efficient transduction of equine adipose-derived mesenchymal stem cells by VSV-G pseudotyped lentiviral vectors

, 2014
Gayle F. Petersen, B. J. Hilbert, Gareth Trope, Wouter Kalle, Pádraig Strappe   +4 more
openalex   +2 more sources

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Correction to "Serum-Free Culture System for Spontaneous Human Mesenchymal Stem Cell Spheroid Formation". [PDF]

Stem Cells Int
europepmc   +1 more source

Molecular mechanisms responsible for mesenchymal stem cell-dependent improvement of islet cell transplantation. [PDF]

Cell Transplant
Volarevic V, Randall Harrell C, Fellabaum C, Djonov V, Volarevic A.   +4 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source