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Micro RNA based MSC EV engineering: Targeting the BMP2 cascade for bone repair
Frontiers in Cell and Developmental Biology, 2023 Mesenchymal stem cell derived extracellular vesicles (MSC EVs) possess excellent immunomodulatory and therapeutic properties. While beneficial, from a translational perspective, extracellular vesicles with consistent functionality and target specificity ...
Chun-Chieh Huang +6 more
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Research in Molecular Medicine, 2020 Background: Cell viability and apoptosis are two crucial factors that may determine cell fate. There are several factors, such as hypoxia, which may be effective in cell processes.
Naser Kalhor Qom +2 more
doaj
Neural Regeneration Research, 2019 Bone marrow-derived mesenchymal stem cells differentiate into neurons under the induction of Schwann cells. However, key microRNAs and related pathways for differentiation remain unclear.
Zhi-Jian Wei +11 more
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Role of geometrical cues in bone marrow-derived mesenchymal stem cell survival, growth and osteogenic differentiation [PDF]
, 2018 Mesenchymal stem cells play a vital role in bone formation process by differentiating into osteoblasts, in a tissue that offers not a flat but a discontinuous three-dimensional (3D) topography in vivo. In order to understand how geometry may be affecting
Bidan CM +10 more
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Comparison of Three Types of Mesenchymal Stem Cells (Bone Marrow, Adipose Tissue, and Umbilical Cord-Derived) as Potential Sources for Inner Ear Regeneration [PDF]
, 2017 In this review, we compared the potential of mesenchymal stem cells derived from bone marrow, adipose tissue and umbilical cord as suitable sources for regeneration of inner ear hair cells and auditory neurons.
Ameneh Mehri-Ghahfarrokhi +5 more
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Mesenchymal stem cells: Figure 1 [PDF]
Thorax, 2012 Mesenchymal Stem cells (MSCs) are stromal cells that can be readily harvested from adult bone marrow and adipose tissue, but also umbilical cords. With respect to respiratory disease, the therapeutic potential of these cells lies in their paracrine effects which underlie their ability to enhance tissue regeneration and modulate immune responses.
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Stem Cells International, 2019 The process of osteoblast switching to alternative mesenchymal phenotypes is incompletely understood. In this study, we tested the ability of the osteoblast/preosteocyte osteogenic cell line, MLO-A5, to also differentiate into either adipocytes or ...
Dongqing Yang +4 more
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Micro- and nanoengineering approaches to control stem cell-biomaterial interactions. [PDF]
, 2011 As our population ages, there is a greater need for a suitable supply of engineered tissues to address a range of debilitating ailments. Stem cell based therapies are envisioned to meet this emerging need. Despite significant progress in controlling stem
Dokmeci, Mehmet R +4 more
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Gingival mesenchymal stem cells
Journal of Oral and Maxillofacial Pathology, 2017 The human gingiva, characterized by its outstanding scarless wound healing properties, is a unique tissue and a pivotal component of the periodontal apparatus, investing and surrounding the teeth in their sockets in the alveolar bone. In the last year's gingival mesenchymal stem/progenitor cells (GMSCs), with promising regenerative and immunomodulatory
K P Mohan Kumar +2 more
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Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy [PDF]
, 2020 Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of studies have shown the beneficial effects of MSC-based therapies to treat different pathologies, including neurological disorders ...
Capilla González, Vivian +4 more
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