Results 41 to 50 of about 1,146,077 (364)
Critical Care Medicine, 2020 Supplemental Digital Content is available in the text. Objectives: The goal of this study was to determine the role of microRNA transfer in mediating the effects of mesenchymal stem cell–derived extracellular vesicles in acute lung injury.
Jiangmei Wang +7 more
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GATA2 regulates differentiation of bone marrow-derived mesenchymal stem cells
Haematologica, 2014 The bone marrow microenvironment comprises multiple cell niches derived from bone marrow mesenchymal stem cells. However, the molecular mechanism of bone marrow mesenchymal stem cell differentiation is poorly understood. The transcription factor GATA2 is
Mayumi Kamata +12 more
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Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis
Cell Proliferation, 2020 Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and microstructural degeneration. The personal and societal costs of osteoporosis are increasing year by year as the ageing of population, posing challenges to public ...
Yu-hua Jiang +4 more
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Research in Molecular Medicine, 2020 Background: Cell viability and apoptosis are two crucial factors that may determine cell fate. There are several factors, such as hypoxia, which may be effective in cell processes.
Naser Kalhor Qom +2 more
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Stem Cells International, 2019 The process of osteoblast switching to alternative mesenchymal phenotypes is incompletely understood. In this study, we tested the ability of the osteoblast/preosteocyte osteogenic cell line, MLO-A5, to also differentiate into either adipocytes or ...
Dongqing Yang +4 more
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Balkan Medical Journal, 2022 Background: Recently, the adipose tissue-derived stromal vascular fraction has become the most popular source for obtaining mesenchymal stem cells because it is less expensive and is easier to perform than bone marrow concentrate harvesting.
E. Çiğdem Karadağ Sarı +1 more
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Mesenchymal stem cells and the lung [PDF]
Respirology, 2013 AbstractMesenchymal stem cells (MSC) are a population of tissue‐resident adult progenitor cells that were originally identified in bone marrow, but have now been identified in many organs including the lung. Although their precise role in organ function remains incompletely defined, mounting evidence suggests that they are an important component of the
Sinclair, Kenneth +2 more
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Neural Regeneration Research, 2019 Bone marrow-derived mesenchymal stem cells differentiate into neurons under the induction of Schwann cells. However, key microRNAs and related pathways for differentiation remain unclear.
Zhi-Jian Wei +11 more
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Dental mesenchymal stem cells [PDF]
Development, 2016 Mammalian teeth harbour mesenchymal stem cells (MSCs), which contribute to tooth growth and repair. These dental MSCs possess many in vitro features of bone marrow-derived MSCs, including clonogenicity, expression of certain markers, and following stimulation, differentiation into cells that have the characteristics of osteoblasts, chondrocytes and ...
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The Pros and Cons of Mesenchymal Stem Cell-Based Therapies
Cell Transplantation, 2019 The need to search for new, alternative treatments for various diseases has prompted scientists and physicians to focus their attention on regenerative medicine and broadly understood cell therapies. Currently, stem cells are being investigated for their
Aleksandra Musiał-Wysocka +2 more
semanticscholar +1 more source