Results 11 to 20 of about 79,337 (314)
Mesenchymal stem cell and hematopoietic stem cell transplantation for vasculitis
Vasculitis is a great therapeutic challenge. Currently, no effective treatments are available. Although biologics are emerging as new therapeutic alternatives, steroids remain the mainstay of the treatment.
Lianming Liao
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Mesenchymal Stem Cell Transplantation for Tissue Repair
There are several characteristics of stem cells that make them unique in comparison with other mammalian cells. First, they exist as unspecialized cells lacking tissue-specific characteristics and they maintain this undifferentiated phenotype until exposed to appropriate signals. Second, they have the capacity for extensive self-renewal.
Frank Barry+3 more
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119: Co-transplantation of mesenchymal stem cells and hematopoietic stem cells [PDF]
Katarina Le Blanc+6 more
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Mesenchymal stem cells and transplant tolerance [PDF]
AbstractDifferent strategies are being tried to induce transplant tolerance in clinical settings; however, none of them are both safe and effective. Mesenchymal stem cells have been found to be potent immunomodulators and immunosuppressants. We discuss in this review different sources of mesenchymal stem cells and the potent role of adipose tissue ...
SC Gopal+4 more
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Mesenchymal stem cells in hematopoietic stem cell transplantation [PDF]
Mesenchymal stromal/stem cells (MSC) of bone marrow (BM) origin not only provide the supportive microenvironmental niche for hematopoietic stem cells (HSC) but are capable of differentiating into various cell types of mesenchymal origin, such as bone, fat and cartilage.
Minoo Battiwalla, Peiman Hematti
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Mesenchymal Stem Cell in Pancreatic Islet Transplantation
Pancreatic islet transplantation is a therapeutic option for achieving physiologic regulation of plasma glucose in Type 1 diabetic patients. At the same time, mesenchymal stem cells (MSCs) have demonstrated their potential in controlling graft rejection, the most fearsome complication in organ/tissue transplantation.
Serena Barachini+6 more
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Mesenchymal stem cells in transplantation and tissue regeneration [PDF]
Mesenchymal stem cells (MSC) were identified in the 1960s as bone marrow cells capable of osteogenic differentiation (Friedenstein and Petrakova, 1966). In the following decennia, these cells were further attributed with the capacity to differentiate into adipogenic, chondrogenic, and myogenic lineages (Pittenger et al., 1999), to secrete trophic ...
Martin J. Hoogduijn, Frank J. M. F. Dor
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Mesenchymal Stem/Stromal Cells in Organ Transplantation
Organ transplantation is essential and crucial for saving and enhancing the lives of individuals suffering from end-stage organ failure. Major challenges in the medical field include the shortage of organ donors, high rates of organ rejection, and long wait times.
Dayanand Deo+2 more
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Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route.
Seyed Mojtaba Hosseini+4 more
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Mesenchymal Stem Cells as Immunomodulators in Transplantation [PDF]
In recent years it has become evident that mesenchymal stem cells (MSCs), also termed mesenchymal stromal cells, have potent immunomodulatory effects in addition to their known ability of organ regeneration and recruitment to sites of injured or inflamed tissue (Caplan 1991; Garin, Chu et al. 2007; Nauta and Fibbe 2007; Bianco, Robey et al.
N. Zghoul, Said Dermime, M. Aljurf
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