Results 11 to 20 of about 433,914 (257)

Cell therapy of congenital corneal diseases with umbilical mesenchymal stem cells: lumican null mice. [PDF]

open access: yesPLoS ONE, 2010
Keratoplasty is the most effective treatment for corneal blindness, but suboptimal medical conditions and lack of qualified medical personnel and donated cornea often prevent the performance of corneal transplantation in developing countries.
Hongshan Liu   +7 more
doaj   +1 more source

Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway

open access: yesNeural Regeneration Research, 2023
Although many therapeutic interventions have shown promise in treating spinal cord injury, focusing on a single aspect of repair cannot achieve successful and functional regeneration in patients following spinal cord injury .
Xin Sun   +10 more
doaj   +1 more source

Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis

open access: yesCell Proliferation, 2020
Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and microstructural degeneration. The personal and societal costs of osteoporosis are increasing year by year as the ageing of population, posing challenges to public ...
Yu-hua Jiang   +4 more
semanticscholar   +1 more source

Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis.

open access: yesBrain : a journal of neurology, 2020
In this study (trial registration: NCT02166021), we aimed to evaluate the optimal way of administration, the safety and the clinical efficacy of mesenchymal stem cell (MSC) transplantation in patients with active and progressive multiple sclerosis. Forty-
P. Petrou   +14 more
semanticscholar   +1 more source

Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation

open access: yesScientific Reports, 2020
Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro   +7 more
doaj   +1 more source

Injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells promotes functional recovery in patients with spontaneous intracerebral hemorrhage: phase I clinical trial

open access: yesNeural Regeneration Research, 2023
Animal experiments have shown that injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells can promote recovery from spinal cord injury.
Xiao-Yin Li   +8 more
doaj   +1 more source

Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration

open access: yesCell Death and Differentiation, 2020
Photoreceptor apoptosis is recognized as one key pathogenesis of retinal degeneration, the counteraction of which represents a promising approach to safeguard visual function.
Chun-Lei Deng   +10 more
semanticscholar   +1 more source

Mesenchymal Stem Cells for Busulfan–Induced Azoospermia: An Experimental Study [PDF]

open access: yesInternational Journal of Medical Arts, 2022
Background: Busulfan is a frequently used chemotherapeutic agent. It exerts harmful effects on male reproduction. Azoospermia is a major cause of male infertility, and stem cell therapy may be a reasonable treatment option.The aim of the work:  The ...
Fawzy Mahmoud Ali Abougalala   +4 more
doaj   +1 more source

Understanding and leveraging cell metabolism to enhance mesenchymal stem cell transplantation survival in tissue engineering and regenerative medicine applications

open access: yesStem Cells, 2020
In tissue engineering and regenerative medicine, stem cell—specifically, mesenchymal stromal/stem cells (MSCs)—therapies have fallen short of their initial promise and hype.
G. E. Salazar-Noratto   +9 more
semanticscholar   +1 more source

Induced Stem Cells as a Novel Multiple Sclerosis Therapy. [PDF]

open access: yes, 2016
Stem cell replacement is providing hope for many degenerative diseases that lack effective therapeutic methods including multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. Transplantation of neural stem cells or
Guan, Yang-Tai   +3 more
core   +2 more sources

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