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Mesenchymal Stem Cell Transplantation for Osteoarthritis
Case Medical Research, 2019semanticscholar +2 more sources
Role of mesenchymal stem cells in hematopoietic stem cell transplantation
Current Opinion in Hematology, 2000Within the bone marrow stroma are multipotential cells which are capable of differentiation into a number of mesenchymal cell lineages. These cells, termed mesenchymal stem cells, have recently been identified and characterized in humans. Many studies indicate that the bone marrow stroma is damaged following bone marrow transplantation.
S M, Devine, R, Hoffman
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Current Opinion in Organ Transplantation, 2012
Mesenchymal stem or stromal cells (MSCs) are multipotent cells with immunomodulatory and regenerative capacities. These properties make MSCs interesting for use as a cell therapeutic agent in solid-organ transplantation (SOT). Their applicability in SOT has recently been evaluated in numerous preclinical and clinical studies, which are reviewed in this
Rhijn, Marieke +2 more
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Mesenchymal stem or stromal cells (MSCs) are multipotent cells with immunomodulatory and regenerative capacities. These properties make MSCs interesting for use as a cell therapeutic agent in solid-organ transplantation (SOT). Their applicability in SOT has recently been evaluated in numerous preclinical and clinical studies, which are reviewed in this
Rhijn, Marieke +2 more
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Lupus, 2018
Systemic lupus erythematosus (SLE) is a chronic autoimmune and inflammatory disorder with involvement of several organs and systems such as the kidney, lung, brain and the hematopoietic system. As the most prevailing organ manifestation, lupus nephritis is the major cause of mortality and morbidity in SLE patients.
A, Fathollahi, N B, Gabalou, S, Aslani
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Systemic lupus erythematosus (SLE) is a chronic autoimmune and inflammatory disorder with involvement of several organs and systems such as the kidney, lung, brain and the hematopoietic system. As the most prevailing organ manifestation, lupus nephritis is the major cause of mortality and morbidity in SLE patients.
A, Fathollahi, N B, Gabalou, S, Aslani
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Transplantation of mesenchymal stem cells in ALS
2012Amyotrophic lateral sclerosis (ALS) is a devastating incurable, neurodegenerative disease that targets motor neurons (MNs) in the primary motor cortex, brainstem, and spinal cord, leading to muscle atrophy, paralysis, and death due to respiratory failure within 2-5 years. Currently, there is no cure for ALS.
Mazzini L +5 more
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Mesenchymal stem cells and haematopoietic stem cell transplantation
Best Practice & Research Clinical Haematology, 2004The bone marrow serves as a reservoir for different classes of stem cells. In addition to haemopoietic stem cells, the bone marrow comprises a population of marrow stromal cells or mesenchymal stem cells (MSCs). These cells exhibit multilineage differentiation capacity, and are able to generate progenitors with restricted developmental potential ...
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Transplantation of Mesenchymal Stem Cells in Multiple Sclerosis
Neuroscience and Behavioral Physiology, 2012To assess safety and tolerability of treatment with autologic multipotent mesenchymal stem cells (MSC) in multiple sclerosis (MS), we have obtained autologic red bone marrow-derived MSC from 8 patients. Proliferation, immunophenotype and caryotype of MSC, their sterility, the absence of hemopoetic cells, chromosomal aberrations and signs of aging were ...
M M, Odinak +7 more
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Mesenchymal Stem Cells in the Induction of Transplantation Tolerance
Transplantation, 2009Mesenchymal stem cells directly suppress ongoing immune responses. Through production of toleragenic cytokines, inhibition of lymphocyte proliferation, delivery of reparative and protective signals after reperfusion injury, and facilitation of hematopoietic chimerism, these cells demonstrate a wide-ranging potential for the development of multifaceted ...
Amelia, Bartholomew +4 more
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Mesenchymal Stromal Cells in Hematopoietic Stem Cell Transplantation
2016Mesenchymal stromal cells (MSCs) comprise a heterogeneous population of multipotent cells that can be isolated from various human tissues and cultured ex vivo for clinical use. Thanks to their secretion of growth factors, immunomodulatory properties and cell-to-cell interactions, MSCs play a key role in the regulation of hematopoiesis and in the ...
Bernardo M. E., Locatelli F.
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Mesenchymal stromal cells and hematopoietic stem cell transplantation
Immunology Letters, 2015Mesenchymal stromal cells (MSCs) comprise a heterogeneous population of multipotent cells that can be isolated from various human tissues and culture-expanded ex vivo for clinical use. Due to their immunoregulatory properties and their ability to secrete growth factors, MSCs play a key role in the regulation of hematopoiesis and in the modulation of ...
Bernardo, M.E., Fibbe, W.E.
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