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Mesenchymal Stem Cells in Allogeneic Transplantation

2003
Graft failure and graft-vs-host disease (GVHD) remain significant obstacles to successful outcome in patients undergoing allogeneic hematopoietic stem cell transplantation. This chapter will introduce a novel cellular therapy, which may address these problems, particularly in high risk patients such as those receiving marginal numbers of hematopoietic ...
Omer N. Koç, Stanton L. Gerson
openaire   +1 more source

Stem cell transplantation and mesenchymal cells to treat autoimmune diseases

La Presse Médicale, 2016
Since the start of the international stem cell transplantation project in 1997, over 2000 patients have received a haematopoietic stem cell transplant (HSCT), mostly autologous, as treatment for a severe autoimmune disease, the majority being multiple sclerosis (MS), systemic sclerosis (SSc) and Crohn's disease. There was an overall 85% 5-year survival
Tyndall A, van Laar JM
openaire   +3 more sources

Mesenchymal Stem Cells and Transplantation Tolerance

2017
Transplantation tolerance meaning stable graft function without rejection episodes in the absence of immunosuppressive drugs while maintaining third-party immune response intact is still not achieved in clinic. Mesenchymal stem cells (MSCs) are believed to fulfill this dream of tolerance due to their immunomodulatory and tolerogenic properties.
Hargovind L. Trivedi, Aruna V. Vanikar
openaire   +1 more source

Cell transplantation: Differential effects of myoblasts and mesenchymal stem cells

International Journal of Cardiology, 2006
Cellular transplantation has emerged as a novel therapeutic option for treatment of ventricular dysfunction. Both skeletal myoblasts (SM) and mesenchymal stem cells (MSC) have been proposed as ideal cell for this aim. The aim of this study is to compare the efficacy of these cells in improving ventricular function and to evaluate the different ...
L C, Guarita-Souza   +11 more
openaire   +2 more sources

Mesenchymal Stem Cells In Islet Transplantion

2013
Type 1 diabetes mellitus (T1DM) is a chronic disorder of glucose metabolism due to autoimmune destruction of insulin producing β-cells. Although insulin therapy is the standard treatment for T1DM, islet transplantation, which has emerged as an alternative to insulin injection, offers a more physiologic means of glycemic control.
openaire   +1 more source

A Phase I Clinical Trial of the Treatment of Crohn’s Fistula by Adipose Mesenchymal Stem Cell Transplantation

Diseases of the Colon & Rectum, 2005
D. García-Olmo   +5 more
semanticscholar   +1 more source

Effects of allogeneic mesenchymal stem cell transplantation in the treatment of liver cirrhosis caused by autoimmune diseases

International Journal of Rheumatic Diseases, 2017
Jun Liang   +8 more
semanticscholar   +1 more source

Co-transplantation of mesenchymal stem cells for efficient spermatogonial stem cell transplantation

2017
Spermatogonial stem cell transplantation (SSCT) is a promising fertility preservation technique for pre-pubertal cancer patients. However, transplanting only SSCs results in low colonization efficiency in mice. This might be due to a deficient SSC niche.
Kadam, Prashant   +3 more
openaire   +1 more source

Clinical Consideration for Mesenchymal Stem Cells in Hematopoietic Stem Cell Transplantation

Transplantation, 2013
Kang-Hsi, Wu   +4 more
openaire   +2 more sources

Mesenchymal Stem Cells in Hematopoietic Stem Cell Transplantation

2011
Peiman Hematti   +2 more
openaire   +1 more source

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