Results 51 to 60 of about 433,914 (257)

Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury

open access: yesTheranostics, 2019
Erectile dysfunction (ED) is an important kind of postoperative complication of pelvic surgery that affects patients' quality of life. Transplantation of mesenchymal stem cells (MSC) has been found to alleviate ED caused by cavernous nerve injury (CNI ...
Zehong Chen   +5 more
semanticscholar   +1 more source

Acellular allogeneic nerve grafting combined with bone marrow mesenchymal stem cell transplantation for the repair of long-segment sciatic nerve defects: biomechanics and validation of mathematical models

open access: yesNeural Regeneration Research, 2016
We hypothesized that a chemically extracted acellular allogeneic nerve graft used in combination with bone marrow mesenchymal stem cell transplantation would be an effective treatment for long-segment sciatic nerve defects.
Ya-jun Li   +4 more
doaj   +1 more source

Safety and Feasibility of Autologous Mesenchymal Stem Cell Transplantation in Chronic Stroke in Indian patients. A four-year follow up

open access: yesJournal of Stem Cells and Regenerative Medicine, 2017
Introduction: Stem cell (SC) therapy has been envisioned as a therapeutic vehicle to promote recovery in resistant neurological diseases. Knowing the logistics and paradigms in recovery processes after Stroke, clinicians have pioneered the ...
A. Bhasin   +4 more
semanticscholar   +1 more source

Propofol combined with bone marrow mesenchymal stem cell transplantation improves electrophysiological function in the hindlimb of rats with spinal cord injury better than monotherapy

open access: yesNeural Regeneration Research, 2015
The repair effects of bone marrow mesenchymal stem cell transplantation on nervous system damage are not satisfactory. Propofol has been shown to protect against spinal cord injury. Therefore, this study sought to explore the therapeutic effects of their
Yue-xin Wang   +6 more
doaj   +1 more source

Parkinson's Disease and Mesenchymal Stem Cells: Potential for Cell-Based Therapy

open access: yesParkinson's Disease, 2012
Cell transplantation is a strategy with great potential for the treatment of Parkinson's disease, and many types of stem cells, including neural stem cells and embryonic stem cells, are considered candidates for transplantation therapy.
Masaaki Kitada, Mari Dezawa
doaj   +1 more source

Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice

open access: yesJournal of Neuroinflammation, 2018
Background Ischemic stroke induced matrixmetallo-proteinase-9 (MMP-9) upregulation, which increased blood-brain barrier permeability. Studies demonstrated that mesenchymal stem cell therapy protected blood-brain barrier disruption from several ...
Zhuo Cheng   +8 more
doaj   +1 more source

Clinical efficacy and safety of mesenchymal stem cell transplantation for osteoarthritis treatment: A meta-analysis

open access: yesPLoS ONE, 2017
Purpose The aim of this study was to evaluate the therapeutic efficacy and safety of mesenchymal stem cells (MSCs) for the treatment of patients with knee osteoarthritis (OA). Materials We performed a meta-analysis of relevant published clinical studies.
Ma Yubo   +5 more
semanticscholar   +1 more source

Dose-Independent Therapeutic Benefit of Bone Marrow Stem Cell Transplantation after MI in Mice

open access: yesBiomedicines, 2020
Several cell populations derived from bone marrow (BM) have been shown to possess cardiac regenerative potential. Among these are freshly isolated CD133+ hematopoietic as well as culture-expanded mesenchymal stem cells. Alternatively, by purifying CD271+
Nicole Zarniko   +4 more
doaj   +1 more source

Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool. [PDF]

open access: yes, 2008
Mesenchymal stem cells (MSCs) from adult somatic tissues may differentiate in vitro and in vivo into multiple mesodermal tissues including bone, cartilage, adipose tissue, tendon, ligament or even muscle. MSCs preferentially home to damaged tissues where
García-Castro, J   +5 more
core  

Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies [PDF]

open access: yes, 2019
Rising numbers of patients with cardiovascular diseases and limited availability of donor hearts require new and improved therapy strategies. Human atrial appendage-derived cells (hAACs) are promising candidates for an allogeneic cell-based treatment. In
Diedrichs, Falk   +5 more
core   +1 more source

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