Neural Regeneration Research, 2015 The repair effects of bone marrow mesenchymal stem cell transplantation on nervous system damage are not satisfactory. Propofol has been shown to protect against spinal cord injury. Therefore, this study sought to explore the therapeutic effects of their
Yue-xin Wang +6 more
doaj +1 more source
Encapsulation of Mesenchymal Stem Cells: Dissecting the Underlying Mechanism of Mesenchymal Stem Cell Transplantation Therapy [PDF]
Neuroscience Insights, 2020 Mesenchymal stem cells (MSCs) are widely considered good candidates for cell transplantation therapy. Various central nervous system disorders have been suggested as suitable targets for MSC transplantation therapy. In this context, a great deal of basic and clinical research has been conducted to explore its clinical uses.
Kyohei Kin, Takao Yasuhara, Isao Date
openaire +3 more sources
Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool. [PDF]
, 2008 Mesenchymal stem cells (MSCs) from adult somatic tissues may differentiate in vitro and in vivo into multiple mesodermal tissues including bone, cartilage, adipose tissue, tendon, ligament or even muscle. MSCs preferentially home to damaged tissues where
García-Castro, J +5 more
core
Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]
, 2012 Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
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The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]
, 2020 The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C +15 more
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Parkinson's Disease and Mesenchymal Stem Cells: Potential for Cell-Based Therapy
Parkinson's Disease, 2012 Cell transplantation is a strategy with great potential for the treatment of Parkinson's disease, and many types of stem cells, including neural stem cells and embryonic stem cells, are considered candidates for transplantation therapy.
Masaaki Kitada, Mari Dezawa
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Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice
Journal of Neuroinflammation, 2018 Background Ischemic stroke induced matrixmetallo-proteinase-9 (MMP-9) upregulation, which increased blood-brain barrier permeability. Studies demonstrated that mesenchymal stem cell therapy protected blood-brain barrier disruption from several ...
Zhuo Cheng +8 more
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A Rat Treated with Mesenchymal Stem Cells Lives to 44 Months of Age [PDF]
, 2016 There is a growing interest in the potential of mesenchymal stem cells (MSCs) for implementing regenerative medicine. We assessed the effect of intravenous administration of human bone marrow-derived MSC on the life span of a single Sprague-Dawley female
Goya, Rodolfo Gustavo +4 more
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Microvesicles as vehicles for tissue regeneration: Changing of the guards [PDF]
, 2016 Purpose of Review: Microvesicles (MVs) have been recognised as mediators of stem cell function, enabling and guiding their regenerative effects. Recent Findings: MVs constitute one unique size class of extracellular vesicles (EVs) directly shed from ...
Davies, R. Wayne +3 more
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Progress in mesenchymal stem cell–based therapy for acute liver failure
Stem Cell Research & Therapy, 2018 Acute liver failure is a life-threatening clinical syndrome characterized by rapid development of hepatocellular necrosis leading to high mortality and resource costs. Numerous treatment strategies for acute liver failure simply prevent complications and
Yong-Hong Wang +4 more
doaj +1 more source