Results 171 to 180 of about 4,624,864 (302)

Mesenchymal Stromal Cells Improve Postoperative Cardiac Dysmaturation in a Juvenile Porcine Model. [PDF]

J Am Heart Assoc
Furuta A, Nishiori H, Aharonyan A, Devoto A, Ejim EJ, Paruchuri R, Henmi S, Kobayashi K, Kobayashi K, Lin S, Wang PC, Tu TW, Ishibashi N.   +12 more
europepmc   +1 more source

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

Adult human mesenchymal stromal cells and the treatment of graft versus host disease

, 2014
Richard P Herrmann, Marian J Sturm Cell and Tissue Therapies, Western Australia, Royal Perth Hospital, Wellington Street, Perth, WA, Australia Abstract: Graft versus host disease is a difficult and potentially lethal complication of hematopoietic stem ...
Herrmann RP, Sturm MJ
core  

Protocol for the isolation and characterization of extracellular vesicles from human mesenchymal stromal cells. [PDF]

STAR Protoc
Collins A, Liddle J, Balsbaugh J, Walker J, Wanczyk H, Finck C, Saneh H.   +6 more
europepmc   +1 more source

The versatility of mesenchymal stromal cells

, 2019
Mesenchymal stromal cells (MSC) are multipotent cells that can be derived from various adult and fetal tissues. The clinical interest in MSC has grown enormously as research revealed that these cells possess hematopoietic supporting, regenerative and immunomodulatory capacities.
openaire   +2 more sources

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Mesenchymal Stromal Cells: From Bench to Bedside and Back. [PDF]

Transfus Med Hemother
Bieback K, Bugert P.
europepmc   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Chondrogenesis of Peripheral Blood-Derived Mesenchymal Stromal Cells. [PDF]

Cells
Ratna HVK, Jeyaraman M, Jeyaraman N, Nallakumarasamy A, Schäfer L, Migliorini F, Muthu S.   +6 more
europepmc   +1 more source

The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin, Hechun Lin, Junming Yu, Chao Ge, Lin Mao, Saihua Zhang, Yizi Jin, Yunyu Wu, Taoyang Chen, Jinjun Li, Hong Li   +10 more
wiley   +1 more source